IP Library › Patent Application 17378267
Patent Application
App. No. 17/378,267

DETECTING COLORECTAL NEOPLASM

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Quick Facts
Patent No.
US None
App. No.
17/378,267
Abstract

Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as colorectal cancer.

Claims (5)

1 . A method comprising:

extracting genomic DNA from a stool sample of a human individual suspected of having or having colorectal cancer,

treating the extracted genomic DNA with bisulfite,

amplifying the bisulfite-treated genomic DNA using primers specific for a CpG site for LRRC4, primers specific for a CpG site for LASS4, and primers specific for a CpG site for PPP2R5C,

measuring a methylation level of the CpG site for LRRC4, the CpG site for LASS4 and the CpG site for PPP2R5C.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 26, 2022
From: AHLQUIST, DAVID A.; TAYLOR, WILLIAM R.; MAHONEY, DOUGLAS W.
To: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
Reel/Frame 058777/0303 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 26, 2022
From: LIDGARD, GRAHAM P.; ALLAWI, HATIM T.
To: EXACT SCIENCES CORPORATION
Reel/Frame 058777/0367 →
MERGER Recorded Jan 24, 2022
From: EXACT SCIENCES DEVELOPMENT COMPANY, LLC
To: EXACT SCIENCES CORPORATION
Reel/Frame 058745/0739 →