IP Library › Granted Patent US 12,290,363
Granted Patent B2
US 12,290,363 · App. 17/390,249 · Granted May 6, 2025

Fluid control devices and methods of using the same

Inventors: Gregory J. Bullington (Seattle, WA); Jay M. Miazga (Langley, WA); Shan E. Gaw (Seattle, WA); Timothy F. Ramsey (Seattle, WA)
Assignee: Magnolia Medical Technologies, Inc.
A61B5/150946A61B5/15003A61B5/150099A61B5/150213A61B5/150221A61B5/150251A61B5/150992B01L3/502B01L2200/026B01L2200/027B01L2200/0684B01L2200/0689B01L2200/141B01L2300/0681B01L2300/14B01L2400/0478B01L2400/0487
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Quick Facts
Patent No.
US 12,290,363
App. No.
17/390,249
Granted
May 6, 2025
Kind
B2
Abstract

A fluid control device includes an inlet configured to be placed directly or indirectly in fluid communication with a bodily fluid source and an outlet configured to be placed in fluid communication with a fluid collection device. The fluid control device has a first state in which a negative pressure differential produced from an external source such as the fluid collection device is applied to the fluid control device to draw an initial volume of bodily fluid from the bodily fluid source, through the inlet, and into a sequestration portion of the fluid control device. The fluid control device has a second state in which (1) the sequestration portion sequesters the initial volume, and (2) the negative pressure differential draws a subsequent volume of bodily fluid, being substantially free of contaminants, from the bodily fluid source, through the fluid control device, and into the fluid collection device.

Claims (16)

1. An apparatus, comprising:

a housing having an inlet configured to be placed in fluid communication with a bodily fluid source and an outlet configured be placed in fluid communication with a fluid collection device, the housing forming a sequestration portion configured to receive an initial volume of bodily fluid from the bodily fluid source; and

an actuator coupled to the housing, the actuator having a first configuration in which a first fluid flow path places the inlet in fluid communication with the sequestration portion and a second configuration in which a second fluid flow path places the inlet in fluid communication with the outlet, the actuator including a diaphragm coupled to at least one seal defining a portion of the first fluid flow path when the diaphragm is in a first state and defining a portion of the second fluid flow path when the diaphragm is in a second state, the diaphragm configured to transition from the first state to the second state when a negative pressure differential through a portion of the actuator is greater than a threshold amount of negative pressure,

wherein the fluid collection device is configured to be placed in fluid communication with the outlet to produce a negative pressure differential (1) within the first fluid flow path operable to draw the initial volume of bodily fluid into the sequestration portion when the actuator is in the first configuration, and (2) within the second fluid flow path operable to draw a sample volume of bodily fluid into the fluid collection device when the actuator is in the second configuration.

2. The apparatus of claim 1 , wherein the initial volume of bodily fluid is sequestered in the sequestration portion when the actuator is in the second configuration.

3. The apparatus of claim 1 , wherein sequestering the initial volume in the sequestration portion reduces contamination in the sample volume.

4. The apparatus of claim 1 , wherein the fluid collection device is a sample reservoir that defines a negative pressure operable to produce the negative pressure differential within the first fluid flow path and the second fluid flow path.

5. The apparatus of claim 1 , wherein the fluid collection device is a syringe configured to be manipulated by a user when in fluid communication with the outlet to produce the negative pressure differential within the first fluid flow path and the second fluid flow path.

6. The apparatus of claim 1 , wherein the actuator is configured to transition from the first configuration to the second configuration in response to a force applied by a user on a portion of the actuator.

7. The apparatus of claim 1 , wherein the actuator includes at least one seal configured to define at least a portion of the first fluid flow path when the actuator is in the first configuration, the at least one seal is configured to define a portion of the second fluid flow path when the actuator is in the second configuration.

8. The apparatus of claim 1 , further comprising:

a flow controller at least partially disposed in the sequestration portion of the housing, the flow controller is configured to establish selective fluid communication between the sequestration portion and the actuator.

9. The apparatus of claim 8 , wherein the flow controller includes a selectively permeable material.

10. The apparatus of claim 9 , wherein the flow controller is configured to transition from a first state in which the selectively permeable material allows a flow of a gas through the flow controller and prevents a flow of bodily fluid through the flow controller, to a second state in which the selectively permeable material prevents a flow of gas and bodily fluid through the flow controller.

11. The apparatus of claim 10 , wherein the flow controller is configured to be placed in the second state in response to at least a portion of the initial volume of bodily fluid saturating the selectively permeable material.

12. The apparatus of claim 10 , wherein the actuator is configured to be transitioned to the second configuration after the flow controller is transitioned to the second state.

Assignments (2)
PATENT SECURITY AGREEMENT Recorded Jan 2, 2024
From: MAGNOLIA MEDICAL TECHNOLOGIES, INC.
To: SYMBIOTIC CAPITAL AGENCY LLC, AS ADMINISTRATIVE AGENT
Reel/Frame 066178/0969 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 12, 2022
From: BULLINGTON, GREGORY J.; MIAZGA, JAY M.; GAW, SHAN E.; RAMSEY, TIMOTHY F.
To: MAGNOLIA MEDICAL TECHNOLOGIES, INC.
Reel/Frame 058634/0470 →
Continuity (5)
Continuation 16129066 · Sep 12, 2018
Provisional Application 62678632 · May 31, 2018
Provisional Application 62634569 · Feb 23, 2018
Provisional Application 62557530 · Sep 12, 2017
Related Publication 20220175284A1 · Jun 9, 2022
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