IP Library Patent Application 17395281
Patent Application
App. No. 17/395,281

DIALYSIS SYSTEM AND METHODS

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Quick Facts
Patent No.
US None
App. No.
17/395,281
Abstract

Dialysis systems and methods are described which can include a number of features. The dialysis systems described can be to provide dialysis therapy to a patient in the comfort of their own home. The dialysis system can be configured to prepare purified water from a tap water source in real-time that is used for creating a dialysate solution. The dialysis systems described also include features that make it easy for a patient to self-administer therapy.

Claims (54)

1 . A method of improving the performance of dialysis tubing that includes an arterial line and also includes a fluid delivery line connecting a fluid source to the dialysis tubing, comprising the steps of:

occluding the arterial line of the dialysis tubing;

opening or releasing a clamping mechanism that interfaces with the fluid delivery line;

modulating a pump speed of a blood pump that interfaces with the dialysis tubing to increase a fluid pressure within the dialysis tubing; and

delivering fluid into the dialysis tubing from the fluid source through the fluid delivery line.

2 . The method of claim 1 , wherein modulating the pump speed of the blood pump comprises increasing a flow rate of the blood pump from a first flow rate to a second flow rate.

3 . The method of claim 1 , wherein modulating the pump speed of the blood pump comprises decreasing a flow rate of the blood pump from a first flow rate to a second flow rate.

4 . The method of claim 1 , wherein modulating the pump speed of the blood pump comprises pulsing a flow rate of the blood pump.

5 . The method of claim 1 , wherein modulating the pump speed of the blood pump comprises decreasing a flow rate of the blood pump from approximately 320 ml/min to approximately 180 ml/min.

6 . The method of claim 1 , further comprising automatically scheduling the occluding, opening, and modulating steps to occur periodically during dialysis therapy.

7 . The method of claim 1 , wherein a portion of the fluid delivery line remains occluded after opening or releasing the clamping mechanism due to prior extended clamping of the fluid delivery line.

8 . The method of claim 1 , wherein a portion of the fluid delivery line remains partially occluded after opening or releasing the clamping mechanism due to prior extended clamping of the fluid delivery line.

9 . The method of claim 1 , further comprising the method steps of:

un-occluding the arterial line;

closing or compressing the clamping mechanism that interfaces with the fluid delivery line; and

initiating dialysis therapy.

10 . A dialysis system, comprising:

a fluid source;

a dialysis tubing set that includes at least an arterial line, a blood pump portion, and a fluid delivery line that connects the fluid source to the dialysis tubing set;

a blood pump configured to interface with the blood pump portion of the dialysis tubing set;

a first clamping mechanism configured to interface with the arterial line;

a second clamping mechanism configured to interface with the fluid delivery line; and

an electronic controller configured to control operation of the blood pump, the first clamping mechanism, and the second clamping mechanism, wherein, during a priming sequence, the electronic controller is configured to:

close or occlude the first clamping mechanism;

open or un-occlude the second clamping mechanism;

modulate a pump speed of the blood pump to increase a fluid pressure within the dialysis tubing set and deliver fluid into the dialysis tubing from the fluid source through the fluid delivery line.

11 . The system of claim 10 , wherein the electronic controller is configured to modulate the pump speed of the blood pump by increasing a flow rate of the blood pump from a first flow rate to a second flow rate.

12 . The system of claim 10 , wherein the electronic controller is configured to modulate the pump speed of the blood pump by decreasing a flow rate of the blood pump from a first flow rate to a second flow rate.

13 . The system of claim 10 , wherein the electronic controller is configured to modulate the pump speed of the blood pump by pulsing a flow rate of the blood pump.

14 . The system of claim 10 , wherein the electronic controller is configured to modulate the pump speed of the blood pump comprises decreasing a flow rate of the blood pump from approximately 320 ml/min to approximately 180 ml/min.

15 . The system of claim 10 , wherein the controller is configured to automatically perform the close, open, and modulate steps periodically during dialysis therapy.

16 . The system of claim 10 , wherein a portion of the fluid delivery line remains occluded after opening or releasing the clamping mechanism due to prior extended clamping of the fluid delivery line.

17 . The system of claim 10 , wherein a portion of the fluid delivery line remains partially occluded after opening or releasing the clamping mechanism due to prior extended clamping of the fluid delivery line.

18 . The system of claim 10 , wherein the electronic controller is further configured to:

un-occlude the arterial line;

close or compress the clamping mechanism that interfaces with the fluid delivery line; and

initiate dialysis therapy.

19 . A method of improving the performance of a dialyzer during dialysis therapy, comprising the steps of:

initiating dialysis therapy;

detecting a difference in pressure between a blood size of the dialyzer and a dialysate side of the dialyzer;

if the difference in pressure exceeds a predetermined threshold:

occluding the arterial line of the dialysis tubing;

opening or releasing a clamping mechanism that interfaces with the fluid delivery line;

modulating a pump speed of a blood pump that interfaces with the dialysis tubing to increase a fluid pressure within the dialysis tubing; and

delivering fluid into the dialysis tubing from the fluid source through the fluid delivery line.

20 . The method of claim 19 , wherein modulating the pump speed of the blood pump comprises increasing a flow rate of the blood pump from a first flow rate to a second flow rate.

21 . The method of claim 19 , wherein modulating the pump speed of the blood pump comprises decreasing a flow rate of the blood pump from a first flow rate to a second flow rate.

22 . The method of claim 19 , wherein modulating the pump speed of the blood pump comprises pulsing a flow rate of the blood pump.

23 . A method of returning blood to a patient after dialysis therapy with a dialysis system that includes a fluid delivery line connecting a fluid receptacle to a dialysis tubing set, comprising the steps of:

opening or releasing a clamping mechanism that interfaces with the fluid delivery line;

backfiltering dialysate through a dialyzer of the dialysis system, into the dialysis tubing set, and into the fluid receptacle via the fluid delivery line;

performing dialysis therapy with the dialysis system including pulling blood into the dialysis tubing set; and

returning the blood to the patient with the backfiltered dialysate in the fluid receptacle.

24 . The method of claim 23 , wherein backfiltering dialysate through the dialyzer further comprises controlling a first dialysate pump that is upstream of the dialyzer to have a faster pump speed than a second dialysate pump that is downstream of the dialyzer.

Assignments (6)
SECURITY INTEREST Recorded Jan 15, 2025
From: OUTSET MEDICAL, INC.
To: PERCEPTIVE CREDIT HOLDINGS IV, LP
Reel/Frame 069880/0739 →
RELEASE OF SECURITY INTEREST Recorded Jan 9, 2025
From: GEMINO HEALTHCARE FINANCE, LLC
To: OUTSET MEDICAL, INC.
Reel/Frame 069800/0767 →
RELEASE OF SECURITY INTEREST Recorded Jan 9, 2025
From: SLR INVESTMENT CORP., AS AGENT
To: OUTSET MEDICAL, INC.
Reel/Frame 069858/0267 →
SECURITY INTEREST Recorded Nov 4, 2022
From: OUTSET MEDICAL, INC.
To: GEMINO HEALTHCARE FINANCE, LLC
Reel/Frame 061654/0556 →
INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Nov 3, 2022
From: OUTSET MEDICAL, INC.
To: SLR INVESTMENT CORP., AS AGENT
Reel/Frame 061879/0764 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 1, 2021
From: HOGARD, MICHAEL EDWARD; ARAGON, MICHAEL; HU, DEAN; KERDOK, AMY ELIZABETH; CAVALIER, ELAINE
To: OUTSET MEDICAL, INC.
Reel/Frame 057674/0871 →