IP Library Granted Patent US 12,516,179
Granted Patent B2
US 12,516,179 · App. 17/423,380 · Granted Jan 6, 2026

Chitosan-based nanocomposite as an antimicrobial agent and corrosion inhibitor

Inventors: Abdul P. Rasheed (Doha, QA); Kashif Rasool (Doha, QA); Ravi P. Pandey (Doha, QA); Khaled A. Mahmoud (Doha, QA)
Assignee: HAMAD BIN KHALIFA UNIVERSITY
C08L5/08A01N25/08A01N59/16C08K5/07C08L97/005B82Y30/00
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Quick Facts
Patent No.
US 12,516,179
App. No.
17/423,380
Granted
Jan 6, 2026
Kind
B2
Abstract

Antimicrobial agents and corrosion inhibitors are widely used as biocides in the oil and gas industry to disinfect the water and inhibit excessive biofilm formation and microbial induced corrosion (MIC) caused mainly by sulfate reducing bacteria (SRB). However, traditional biocides may induce bacterial resistance and/or be detrimental to environment by forming harmful disinfection byproducts. A chitosan-based nanocomposite is successfully implemented as a novel green biocide for treatment of water, the inhibition of sulfate reducing bacteria (SRB) and reduction of biocorrosion on SS400 carbon steel.

Claims (10)

1 . A composition comprising chitosan and lignosulfonic acid, wherein the chitosan and lignosulfonic acid are covalently crosslinked, and wherein the composition comprises nanospheres.

2 . The composition of claim 1 , wherein the chemical crosslinking is mediated by formaldehyde, sulfuric acid, and sodium sulfate.

3 . The composition of claim 1 , wherein the nanospheres have average diameters of about 150 nm to about 200 nm.

4 . The composition of claim 1 , wherein the nanospheres have average diameters of about 40 nm.

5 . The composition of claim 1 , wherein the mass ratio of chitosan: lignosulfonic acid ranges from about 1:2 to about 2:1.

6 . The composition of claim 1 , wherein the mass ratio of chitosan: lignosulfonic acid is about 1:1.

7 . The composition of claim 1 , wherein the chitosan has about 85% degree of deacetylation.

8 . The composition of claim 1 , wherein the chitosan has a molecular weight ranging from about 50000 Da to about 375000 Da.

9 . The composition of claim 1 , wherein the composition is an antimicrobial composition.

10 . The composition of claim 1 , wherein the nanospheres have a zeta potential of about +34.25 mV.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 17, 2025
From: QATAR FOUNDATION FOR EDUCATION, SCIENCE & COMMUNITY DEVELOPMENT
To: HAMAD BIN KHALIFA UNIVERSITY
Reel/Frame 069936/0656 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 9, 2022
From: RASHEED, ABDUL P.; RASOOL, KASHIF; PANDEY, RAVI P.; MAHMOUD, KHALED A.
To: QATAR FOUNDATION FOR EDUCATION, SCIENCE AND COMMUNITY DEVELOPMENT
Reel/Frame 059355/0688 →
Continuity (2)
Provisional Application 62794570 · Jan 19, 2019
Related Publication 20220127436A1 · Apr 28, 2022
References Cited (18)
US 20030129730A1 · Chenite · 2003 [cited by examiner]
US 20160168711A1 · Wasserfallen · 2016 [cited by examiner]
US 20160369065A1 · Theivendran · 2016 [cited by examiner]
US 20180346690A1 · Wu · 2018 [cited by examiner]
CN 102108172A · 2011 [cited by examiner]
WO WO2009155417A1 · 2009 [cited by examiner]
WO WO2015187631A1 · 2015 [cited by examiner]
Machine translation for CN-102108172A (Year: 2011). [cited by examiner]
Machine translation of CN-102108172-A (Year: 2011). [cited by examiner]
Kim et al.; Chitosan-lignosulfonates sono-chemically prepared nanoparticles: Characterisation and potential applications; Elsevier; Colloids and Surfaces B: Biointerfaces 103 (2013) 1-8 (Year: 2013). [cited by examiner]
Beisl et al.; Lignin from Micro-to Nanosize: Applications; MDPI; Int. J. Mol. Sci. 2017, 18, 2367 (Year: 2017). [cited by examiner]
Aldrich Product Specification Sheet for Chitosan from shrimp shells, practical grade (accessed Jun. 2025) (Year: 2025). [cited by examiner]
Aldrich Chitiosan (accessed Jun. 2025) (Year: 2021). [cited by examiner]
Google Search; calcium lignosulfonates (accessed Jun. 2025) (Year: 2025). [cited by examiner]
International Search Report for related International Application No. PCT/QA2020/050003; report dated Nov. 26, 2020; (4 pages). [cited by applicant]
Written Opinion for related International Application No. PCT/QA2020/050003; report dated Nov. 26, 2020; (6 pages). [cited by applicant]
El-Mekawy, et al.; “Recent trends in smart and flexible three dimensional cross-linked polymers: synthesis of chitosan—ZnO nanocomposite hydrogels for insulin drug delivery”; Medchemcomm, vol. 8, Feb. 28, 2017 [retrieve… [cited by applicant]
Kim et al; “Chitosan-lignosulfonates sono-chemically prepared nanoparticles: Characterisation and potential applications, Colloids and Surfaces B”; Biointerfaces, vol. 103, Oct. 30, 2012 [retrieved on Aug. 27, 2020]. Re… [cited by applicant]