IP Library › Granted Patent US 12,303,117
Granted Patent B2
US 12,303,117 · App. 17/454,226 · Granted May 20, 2025

Asymmetric occluder device

Inventors: Elaheh Malakan Rad (Jena, DE); Ziyad Mousa Hijazi (Jena, DE)
Assignee: Occlutech Holding AG
A61B17/0057A61L31/022A61L31/04A61B2017/00358A61B2017/00575A61B2017/00592A61B2017/00606A61B2017/00623A61B2017/00867A61B2017/00876
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 12,303,117
App. No.
17/454,226
Granted
May 20, 2025
Kind
B2
Abstract

An asymmetric occlusion device for occluding an opening in a body tissue where part of the opening is defined by a partial inadequate rim. The asymmetric occlusion device includes a waist portion having a distal end extending to a proximal end. The waist portion is of non-woven material extending around a longitudinal axis opening. The occlusion device further includes a pair of asymmetric occluder disks attached to the waist. The asymmetric distal and proximal occluder disks are formed of shape memory material. The asymmetric occluder disks include a short arm extending from the waist and an extended arm extending from the waist. The extended arm exceeds the length of the first short arm. The density of the first short arm exceeds the density of the second extended arm.

Claims (31)

1. A septal defect occluder for positioning in a defect in an atrial septum, the occluder comprising:

a braiding shaped to form a first disk and a second disk, wherein the first disk and the second disk are joined by a waist portion;

the waist portion having a width that is smaller than a width of the first disk and the second disk;

a hub joining ends of wires of the braiding, the hub protruding from an exterior surface of at least one of the first or second disk;

wherein the hub is off-center of the waist portion such that braids of at least one of the first and second disks radiating in a first direction extend further from the hub along the disk than braids radiating in a second direction along the disk opposite the first direction;

wherein the braids of the at least one of the first and second disks radiating in the second direction are more dense than the braids radiating in the first direction thereby providing an asymmetry in thickness of the braids in the first and second direction from the hub;

wherein the first and second disks curve inward towards the waist portion and each of the first and second disks comprises a rim being configured to clamp onto a septal wall;

and including a delivery attachment mechanism arranged off-center of the waist portion for attachment to a delivery device.

2. The septal defect occluder of claim 1 wherein the hub is defined by an extension located on the first disk.

3. The septal defect occluder of claim 2 wherein the extension includes a channel extending through the extension.

4. The septal defect occluder of claim 1 wherein the first disk is distal of the second disk.

5. The septal defect occluder of claim 1 wherein the first disk is larger than the second disk.

6. The septal defect occluder of claim 1 wherein at least one of the first disk and the second disk has an ovoid shape.

7. The septal defect occluder of claim 1 wherein at least one of the first disk and the second disk includes a radiopaque marker.

8. The septal defect occluder of claim 1 wherein at least one of the first and second disks comprises a short arm extending in a first direction from the hub, and a long arm extending in a second direction from the hub, wherein the first direction is different from the second direction.

9. The septal defect occluder of claim 8 , wherein the short arm is thicker than the long arm.

10. The septal defect occluder of claim 1 , wherein the width of the waist portion is from 1 to 4 mm larger in size than the defect in which the septal defect occluder is to be positioned so as to provide a stopper-like plug to the defect.

11. A septal defect occluder for positioning in a defect in an atrial septum, the occluder comprising:

a braiding shaped to form a first disk and a second disk, wherein the first and second disks are joined by a waist portion and curve inward towards the waist portion;

the waist portion having a width that is smaller than a width of the first disk and the second disk;

a hub joining ends of wires of the braiding, the hub protruding from an exterior surface of at least one of the first or second disk;

wherein the hub is off-center of the waist portion such that braids of at least one of the first and second disks radiating in a first direction extend further from the hub along the disk than braids radiating in a second direction along the disk opposite the first direction;

wherein the braids of the at least one of the first and second disks radiating in the second direction are more dense than the braids radiating in the first direction thereby providing an asymmetry in thickness of the braids in the first and second direction and including a delivery attachment mechanism arranged off-center of the waist portion for attachment to a delivery device.

12. The septal defect occluder of claim 11 , wherein the first and second disks each comprises a rim being configured to clamp onto a septal wall;

and wherein the septal defect occluder comprises a channel extending through the septal defect occluder.

13. The septal defect occluder of claim 11 wherein the hub is defined by an extension located on the first disk.

14. The septal defect occluder of claim 13 wherein the extension includes a channel extending through the extension.

15. The septal defect occluder of claim 11 wherein the first disk is distal of the second disk.

16. The septal defect occluder of claim 15 wherein the first disk is larger than the second disk.

17. The septal defect occluder of claim 11 wherein at least one of the first disk and the second disk has an ovoid shape.

18. The septal defect occluder of claim 11 , wherein the width of the waist portion is from 1 to 4 mm larger in size than the septal defect in which the septal defect occluder is to be positioned so as to provide a stopper-like plug to the septal defect.

Assignments (2)
SECURITY INTEREST Recorded Sep 19, 2023
From: OCCLUTECH GMBH
To: NORDIC TRUSTEE & AGENCY AB
Reel/Frame 064953/0324 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 21, 2023
From: OCCLUTECH HOLDING AG
To: OCCLUTECH GMBH
Reel/Frame 064345/0754 →
Continuity (4)
Continuation 16120195 · Aug 31, 2018
Continuation 14292033 · May 30, 2014
Provisional Application 61828991 · May 30, 2013
Related Publication 20220061828A1 · Mar 3, 2022
References Cited (34)
US 5944738A · Amplatz et al. · 1999 [cited by applicant]
US 6468303B1 · Amplatz et al. · 2002 [cited by applicant]
US 20040098121A1 · Opolski · 2004 [cited by applicant]
US 20060136043A1 · Cully et al. · 2006 [cited by applicant]
US 20060224183A1 · Freudenthal · 2006 [cited by applicant]
US 20080200945A1 · Amplatz et al. · 2008 [cited by applicant]
US 20090171386A1 · Amplatz et al. · 2009 [cited by applicant]
US 20090228038A1 · Amin · 2009 [cited by applicant]
US 20090312789A1 · Kassab et al. · 2009 [cited by applicant]
US 20100204662A1 · Orlov et al. · 2010 [cited by applicant]
US 20110054519A1 · Neuss · 2011 [cited by applicant]
US 20120071918A1 · Amin et al. · 2012 [cited by applicant]
US 20140039543A1 · Willems et al. · 2014 [cited by applicant]
WO WO2008040555A2 · 2008 [cited by applicant]
Abaci, Adnan, M.D. et al., “Short and Long Term Complications of Device Closure of Atrial Septal Defect and Patent Foramen Ovale: Meta-Analysis of 28,142 Patients from 203 Studies,” [cited by applicant]
Srilatha Alapati, Srilatha et al., “Historical Aspects of Transcatheter Occlusion of Atrial Septal Defects,” [cited by applicant]
Amin, Zahid, “Transcatheter Closure of Secundum Atrial Septal Defects,” [cited by applicant]
Chan, Kam Tim, et al., “Retrieval of an Embolized Amplatzer Septal Occluder,” [cited by applicant]
Fischer, G., et al., “Transcatheter closure of secundum atrial septal defects with the new self-centering Amplatzer Septal Occluder,” [cited by applicant]
Gokaslan, Gokhan, et al., “Urgent surgical management for embolized occlude devices in childhood: single center experience,” [cited by applicant]
Kannan, Bhava Ramalingam Jawahar, M.D., et al., “Transcatheter Closure of Very Large (≥ 25 mm) Atrial Septal Defects Using the Amplatzer Septal Occluder,” [cited by applicant]
Kazmouz, Suhaib, M.D., et al., “Transcatheter Closure of Secundum trial Septal Defects,” [cited by applicant]
King, Terry Dean, et al., “Chapter 4: Historical perspectives on ASD device closure,” [cited by applicant]
King, Terry D., et al., “Secundum Atrial Septal Defect, Nonoperative Closure During Cardiac Catheterization,” [cited by applicant]
Knirsch, W., et al., “Challenges Encountered During Closure of Atrial Septal Defects,” [cited by applicant]
Levi, Daniel S., M.D., et al., “Embolization and Retrieval of the Amplatzer Septal Occluder,” [cited by applicant]
Li, Sui-Shuang, et al., “Feasibility and Safety of Transthoracic Echocardiography-Guided Transcatheter Closure of Atrial Septal Defects with Deficient Superior-Anterior Rims,” [cited by applicant]
Love, Barry A., M.D., et al., “Advantages of the GORE® HELEX® Septal Occluder for Closure of Atrial Septal Defect with a Deficient Retroaortic Rim,” [cited by applicant]
Moore, John, M.D., et al., “Transcatheter Device Closure of Atrial Septal Defects,” [cited by applicant]
Ohno, Naoki, M.D., et al., “Characteristics of Secundum Atrial Septal Defects Not Percutaneously Closed,” [cited by applicant]
Papa, Marco, M.D., et al., “Feasibility and Safety of Transcatheter Closure of Atrial Septal Defects with Deficient Posterior Rim,” [cited by applicant]
Podnar, Tomaž, M.D., et al., “Morphological Variations of Secundum-Type Atrial Septal Defects: Feasibility for Percutaneous Closure Using Amplatzer Septal Occluders,” [cited by applicant]
Vaidyanathan, Balu, DM, et al., “Transesophageal Echocardiography for Device Closure of Atrial Septal Defects, Case Selection, Planning, and Procedural Guidance,” [cited by applicant]
Yared, Kibar, M.D., et al., “Echocardiographic Assessment of Percutaneous Patent Foramen Ovale and Atrial Septal Defect Closure Complications,” [cited by applicant]