IP Library › Granted Patent US 12,232,964
Granted Patent B2
US 12,232,964 · App. 17/456,901 · Granted Feb 25, 2025

Bioabsorbable textiles and methods for joint function restoration

Inventors: Stefano Agnello (Grotte, IT); Edward Ahn (Dover, MA); Matteo Centola (Padua, IT); Steven W. Ek (Bolton, MA); Stephen J. Kennedy (Hudson, NH); Matthew M. Mannarino (Burlington, MA); Elvira Marchetto (Abano Terme, IT); Sonali Puri (Ashland, MA); Robert Richard (Wakefield, RI); Sara Simoncioni (Senigallia, IT)
Assignee: Anika Therapeutics, Inc.
A61F2/30A61L27/20A61L27/32A61L27/58D02G3/448D03D1/00D03D19/00A61F2002/30062A61F2210/0004D10B2331/04D10B2401/12D10B2509/00
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Quick Facts
Patent No.
US 12,232,964
App. No.
17/456,901
Granted
Feb 25, 2025
Kind
B2
Abstract

A bioabsorbable textile for the restoration of the joint function whereas the joint is affected by partial thickness tears, small to medium full-thickness tears, large to massive full-thickness tears, acute and chronic/degenerative tears. The bioabsorbable textile may comprise polymeric yarns interconnected to form a weave or knitted configuration, wherein said bioabsorbable textile provides a combined mechanical and biological augmentation in the target joint tissue. The bioabsorbable textile may be implanted in combination with fixation tools during open, mini-open or arthroscopic repair/augmentation procedures of joint tissue tears.

Claims (13)

1. A bioabsorbable textile for joint function restoration comprising polymeric yarns,

wherein at least one of said polymeric yarns comprises a hyaluronic acid derivative, and

the at least polymeric yarn having:

linear mass density from 30 tex to about 100 tex;

a breaking strength in the range from about 1 N to about 100 N; and

an extension at break from about 1% to about 30% and

wherein the bioabsorbable textile is a knitted structure or a leno-wave structure.

2. The bioabsorbable textile according to claim 1 , wherein said hyaluronic acid derivative is an ester.

3. The bioabsorbable textile according to claim 2 , wherein said hyaluronic acid derivative is a benzyl ester.

4. The bioabsorbable textile according to claim 3 , wherein the esterification degree of said hyaluronic acid derivative ranges between 80% to 100%.

5. The bioabsorbable textile according to claim 1 , wherein said bioabsorbable textile is coated with an osteo-inductive and/or osteo-conductive material selected from the group consisting of hydroxyapatite, calcium phosphates, bone cements, demineralized bone matrix, titanium, magnesium, strontium, bioglasses, other resorbable glasses, and a combination thereof.

6. The bioabsorbable textile according to claim 1 , wherein the bioabsorbable textile is added to a biological component selected from the group consisting of bone marrow aspirate, bone marrow aspirate concentrate, mesenchymal stem cells, bone marrow stem cells, adipose-derived stem cells, amniotic cells, micronized amniotic membrane, partially- or fully-digested tissue biopsies, aspirated adipose tissue, platelet rich plasma, autologous conditioned plasma, growth factors, and a combination thereof.

7. The bioabsorbable textile according to claim 1 , wherein the bioabsorbable textile is characterized by a volumetric and by a thickness swelling ratio in the range from about 0.1% to about 150%.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 5, 2024
From: ANIKA THERAPEUTICS S.R.L.
To: ANIKA THERAPEUTICS, INC.
Reel/Frame 069490/0911 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 17, 2022
From: AGNELLO, STEFANO; AHN, EDWARD; CENTOLA, MATTEO; EK, STEVEN W.; MANNARINO, MATTHEW M.; MARCHETTO, ELVIRA; PURI, SONALI; RICHARD, ROBERT; SIMONCIONI, SARA; KENNEDY, STEPHEN J.
To: ANIKA THERAPEUTICS S.R.L.
Reel/Frame 059114/0161 →
Continuity (2)
Provisional Application 63120232 · Dec 2, 2020
Related Publication 20220168105A1 · Jun 2, 2022
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