IP Library › Granted Patent US 12,310,851
Granted Patent B2
US 12,310,851 · App. 17/460,183 · Granted May 27, 2025

Method for deploying a prosthetic heart valve

Inventors: David M. Taylor (Lake Forest, CA); Philippe Marchand (Munich, DE); Larry L. Wood (Newport Beach, CA); Robert Bowes (Trabuco Canyon, CA)
Assignee: EDWARDS LIFESCIENCES CORPORATION
A61F2/243A61F2/2418A61F2/2439A61F2/95A61F2/97A61F2/2412A61F2230/0076A61F2250/0008A61F2250/0029A61F2250/0036A61F2250/0059
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Quick Facts
Patent No.
US 12,310,851
App. No.
17/460,183
Granted
May 27, 2025
Kind
B2
Abstract

A method for deploying an expandable prosthetic heart valve in a patient includes introducing a guidewire into a patient and advancing the guidewire through a vasculature of a patient to a deployment site. A distal end portion of a delivery apparatus and the prosthetic heart valve mounted in a radially compressed configuration along the distal end portion are advanced over the guidewire. The prosthetic heart valve is positioned at the deployment site. A screw mechanism is rotated, which exerts an axially directed onto the prosthetic heart valve, causing the prosthetic heart valve to radially expand from the radially compressed configuration to a radially expanded configuration.

Claims (35)

1. A method for deploying an expandable prosthetic heart valve in a patient, the method comprising:

introducing a guidewire into a patient and advancing the guidewire through a vasculature of a patient to a deployment site;

advancing over the guidewire a distal end portion of a delivery apparatus and the prosthetic heart valve mounted in a radially compressed configuration along the distal end portion;

positioning the prosthetic heart valve at the deployment site, the prosthetic heart valve comprising a frame and one or more leaflet members disposed within the frame; and

rotating a screw mechanism, the rotating resulting in exertion of a proximally directed force on a distal end of the prosthetic heart valve and a distally directed force on a proximal end of the prosthetic heart valve, wherein the proximally directed force and the distally directed force exerted on the prosthetic valve forces the prosthetic heart valve to radially expand from the radially compressed configuration to a radially expanded configuration;

wherein the delivery apparatus comprises an actuator coupled to the screw mechanism and rotating the screw mechanism comprises actuating the actuator to produce rotation of the screw mechanism.

2. The method of claim 1 , wherein the actuator comprises a rotatable knob on a handle of the delivery apparatus, wherein the rotatable knob is coupled to a proximal end portion of the screw mechanism, and wherein rotating the screw mechanism comprises rotating the rotatable knob to produce rotation of the screw mechanism.

3. The method of claim 1 , wherein the delivery apparatus comprises a handle that includes visual indicia that indicates an amount of expansion of the prosthetic heart valve.

4. The method of claim 1 , wherein the actuator comprises a motor.

5. The method of claim 4 , wherein the delivery apparatus comprises a gear mechanism, wherein the screw mechanism is operatively coupled to the motor by the gear mechanism.

6. The method of claim 5 , wherein the gear mechanism comprises a gear reduction mechanism coupled to the actuator.

7. The method of claim 6 , wherein the gear reduction mechanism receives an input torque from the actuator and rotates the screw mechanism at an output torque different than the input torque to expand the expandable prosthetic heart valve.

8. The method of claim 6 , wherein the gear reduction mechanism receives an input speed from the actuator and rotates the screw mechanism at an output speed different than the input speed to expand the expandable prosthetic heart valve.

9. The method of claim 1 , further comprising releasing the prosthetic heart valve from the delivery apparatus after radially expanding the prosthetic heart valve.

10. A method for deploying an expandable prosthetic heart valve in a patient, the method comprising:

introducing a guidewire into a patient and advancing the guidewire through a vasculature of a patient to a deployment site;

advancing over the guidewire a distal end portion of a delivery apparatus and the prosthetic heart valve mounted in a radially compressed configuration along the distal end portion;

positioning the prosthetic heart valve at the deployment site; and

rotating an externally threaded screw in a first direction, wherein the threaded screw extends through an internally threaded portion of an expansion mechanism, wherein the rotating of the threaded screw produces proximally and distally directed forces acting on the prosthetic heart valve to cause distal and proximal ends of the prosthetic heart valve to move closer to each other, wherein the proximally and distally directed forces acting on the prosthetic valve forces the prosthetic heart valve to radially expand from the radially compressed configuration to a radially expanded configuration.

11. The method of claim 10 , further comprising releasing the prosthetic heart valve from the delivery apparatus after radially expanding the prosthetic heart valve.

12. The method of claim 11 , wherein releasing the prosthetic heart valve from the delivery apparatus comprises pulling in a proximal direction a wire member connected to the prosthetic heart valve to release the prosthetic heart valve from the delivery apparatus.

13. The method of claim 10 , further comprising rotating the screw of the expansion mechanism in a second direction to radially compress the prosthetic heart valve.

14. The method of claim 10 , wherein the prosthetic heart valve comprises an expandable frame member and one or more leaflet members attached to the frame member.

15. The method of claim 14 , wherein the frame member comprises a plurality of diamond shaped cells.

16. The method of claim 10 , wherein the internally threaded portion of the expansion mechanism comprises an internally threaded distal end portion of the expansion mechanism.

17. The method of claim 16 , wherein the externally threaded screw extends through a non-threaded proximal end portion of the expansion mechanism.

18. The method of claim 17 , wherein the rotating the externally threaded screw of the expansion mechanism in the first direction decreases a distance between the threaded distal end portion and the non-threaded proximal end portion of the expansion mechanism.

19. A method for deploying an expandable prosthetic heart valve in a patient, the method comprising:

introducing a guidewire into a patient and advancing the guidewire through a vasculature of a patient to a deployment site;

advancing over the guidewire a distal end portion of a delivery apparatus and the prosthetic heart valve mounted in a radially compressed configuration along the distal end portion;

positioning the prosthetic heart valve at the deployment site;

rotating a screw mechanism, which exerts a proximally directed force on a distal end of the prosthetic heart valve and a distally directed force on a proximal end of the prosthetic heart valve, thereby causing the prosthetic heart valve to radially expand from the radially compressed configuration to a radially expanded configuration in which the prosthetic heart valve contacts a native heart valve annulus;

releasing the prosthetic heart valve from the delivery apparatus and removing the delivery apparatus from the patient's vasculature after radially expanding the prosthetic heart valve; and

wherein the delivery apparatus comprises a handle that includes visual indicia that indicates an amount of expansion of the prosthetic heart valve.

20. The method of claim 19 , wherein releasing the prosthetic heart valve from the delivery apparatus comprises releasing the prosthetic heart valve from the screw mechanism.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 10, 2021
From: TAYLOR, DAVID M.; MARCHAND, PHILIPPE; WOOD, LARRY L.; BOWES, ROBERT
To: EDWARDS LIFESCIENCES CORPORATION
Reel/Frame 057451/0870 →
Continuity (7)
Continuation 16130726 · Sep 13, 2018
Continuation 14880616 · Oct 12, 2015
Continuation 14338001 · Jul 22, 2014
Continuation 13910348 · Jun 5, 2013
Continuation 12396378 · Mar 2, 2009
Provisional Application 61032851 · Feb 29, 2008
Related Publication 20210386540A1 · Dec 16, 2021
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