IP Library › Granted Patent US 12,090,180
Granted Patent B2
US 12,090,180 · App. 17/496,919 · Granted Sep 17, 2024

Microbial hyperswarmers and uses thereof

Inventors: Sridhar Mani (Riverdale, NY); Libusha Kelly (Brooklyn, NY); Hao Li (Elmsford, NY)
Assignee: Albert Einstein College of Medicine
A61K35/744A61K9/48A61K35/741A61K35/742C12N1/20G01N33/483A61K9/0031A61K9/0053A61P1/14Y02A50/30
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Quick Facts
Patent No.
US 12,090,180
App. No.
17/496,919
Granted
Sep 17, 2024
Kind
B2
Abstract

Bacterial hyperswarmers are disclosed for treatment, prevention and diagnosis of conditions such as intestinal inflammation.

Claims (7)

1. A method of isolating a single bacterial strain from a complex bacterial mix in a fecal material, the method comprising

isolating bacterial hyperswarmers as a single bacterial strain from the fecal material on a plate agar assay under aerobic conditions to provide isolated bacterial hyperswarmers; and

propagating the isolated bacterial hyperswarmers in culture to isolate a single bacterial strain.

2. The method of claim 1 , wherein the fecal material is from an animal model of inflammation or from an animal with an intestinal inflammation.

3. The method of claim 2 , wherein the animal is a human.

4. The method of claim 3 , wherein the human has irritable bowel disease.

5. The method of claim 2 , wherein the animal is a farm animal.