CAPSULE CONTAINMENT OF DRIED REAGENTS
Disclosed herein are methods and devices for preparing a dried reagent for long term storage and rehydrating and mixing the dried reagent.
1 . A microfluidic device comprising:
an oval-shaped raised surface on the microfluidic device, wherein said oval-shaped raised surface comprises an inlet, an outlet, and an edge; and
a reagent storage component having a capsule capable of holding a liquid or a solid sample, said capsule comprising an inner surface extending from the bottom of said capsule to an oval-shaped opening at the top of the capsule, wherein said inner surface is substantially smooth and comprises a concave shape extending from the bottom of the capsule,
wherein engagement between said oval-shaped opening and said edge forms a fluid tight seal to compartmentalize said capsule with respect to the inlet and the outlet of the oval shaped raised surface.
2 . The device of claim 1 the reagent storage component further comprising:
a planar layer affixed around the oval-shaped opening of said capsule and oriented in the same plane as the oval-shaped opening of said capsule, wherein said planar layer comprises a top surface and a bottom surface, said top surface aligned with the inner surface of said capsule at said oval-shaped opening to provide a continuous surface.
3 . The device of claim 1 , wherein said capsule comprises a mixing element.
4 . The device of claim 3 , wherein said mixing element comprises a magnetic bead.
5 . The device of claim 1 , wherein said capsule comprises a dried reagent.