Patent Application
Utility
App. No. 17/529,818
· Confirmation No. 5464
USE OF METHYLNALTREXONE AND RIFAXIMIN FOR TREATMENT OF INCREASED GUT PERMEABILITY OR ASSOCIATED DISORDERS
Inventors:
Lorin K. Johnson, XiaoJun Nicole Deng, William J. Jo Siu, Robert J. Israel, Zeev Heimanson
Applicant:
Bausch Health Ireland Limited
Non Final Action Mailed
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Code | Description | Pages | ||
|---|---|---|---|---|---|
| 2026-07-08 | CTNF |
Non-Final Rejection | 9 | View | |
| 2026-07-08 | 892 |
List of references cited by examiner | 1 | View | |
| 2026-07-08 | SRFW |
Search information including classification, databases and other search related notes | 2 | View | |
| 2026-07-08 | SRNT |
Examiner's search strategy and results | 17 | View | |
| 2026-03-12 | A.NE |
Response After Final Action | — | View | |
| 2026-03-12 | RCEX |
Request for Continued Examination (RCE) | 2 | View | |
| 2026-03-12 | XT/ |
Extension of Time | 2 | View | |
| 2026-03-12 | AMSB |
Amendment Submitted/Entered with Filing of Continued Prosecution Application (CPA)/Request for Continued Examination(RCE) | 1 | View | |
| 2026-03-12 | CLM |
Claims | 3 | View | |
| 2026-03-12 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2026-03-12 | N417.PYMT |
Electronic Fee Payment | 2 | View | |
| 2026-03-12 | REM |
Applicant Arguments/Remarks Made in an Amendment | 2 | View | |
| 2026-03-12 | REM |
Applicant Arguments/Remarks Made in an Amendment | 1 | View | |
| 2026-03-12 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2025-10-14 | CTFR |
Final Rejection | 11 | View | |
| 2025-10-14 | 892 |
List of references cited by examiner | 1 | View | |
| 2025-10-14 | SRFW |
Search information including classification, databases and other search related notes | 1 | View | |
| 2025-10-14 | SRNT |
Examiner's search strategy and results | 1 | View | |
| 2025-10-14 | SRNT |
Examiner's search strategy and results | 4 | View | |
| 2025-10-14 | SRNT |
Examiner's search strategy and results | 13 | View | |
| 2025-06-25 | A... |
Amendment/Request for Reconsideration-After Non-Final Rejection | — | View | |
| 2025-06-25 | A... |
Amendment/Request for Reconsideration-After Non-Final Rejection | 1 | View | |
| 2025-06-25 | CLM |
Claims | 3 | View | |
| 2025-06-25 | REM |
Applicant Arguments/Remarks Made in an Amendment | 4 | View | |
| 2025-06-25 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2025-06-25 | N417.PYMT |
Electronic Fee Payment | 2 | View | |
| 2025-06-25 | XT/ |
Extension of Time | 2 | View | |
| 2025-06-25 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2025-02-25 | CTNF |
Non-Final Rejection | 14 | View | |
| 2025-02-25 | 892 |
List of references cited by examiner | 1 | View | |
| 2025-02-25 | SRFW |
Search information including classification, databases and other search related notes | 1 | View | |
| 2025-02-25 | 1449 |
List of References cited by applicant and considered by examiner | 9 | View | |
| 2025-02-25 | SRNT |
Examiner's search strategy and results | 5 | View | |
| 2025-02-25 | SRNT |
Examiner's search strategy and results | 2 | View | |
| 2025-02-25 | SRNT |
Examiner's search strategy and results | 10 | View | |
| 2025-02-25 | SRNT |
Examiner's search strategy and results | 14 | View | |
| 2025-02-25 | SRNT |
Examiner's search strategy and results | 4 | View | |
| 2024-10-30 | ELC. |
Response to Election / Restriction Filed | 3 | View | |
| 2024-10-30 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2024-08-30 | CTRS |
Requirement for Restriction/Election | 6 | View | |
| 2024-08-30 | SRFW |
Search information including classification, databases and other search related notes | 1 | View | |
| 2024-08-30 | FWCLM |
Index of Claims | 1 | View | |
| 2024-06-06 | N570 |
Communication - Re: Power of Attorney (PTOL-308) | 1 | View | |
| 2024-06-06 | N570 |
Communication - Re: Power of Attorney (PTOL-308) | 1 | View | |
| 2024-05-24 | REF.OTHER |
Other reference-Patent/Application/Search Documents | 11 | View | |
| 2024-05-24 | N417 |
Electronic Filing System Acknowledgment Receipt | 4 | View | |
| 2024-05-24 | FOR |
Foreign Reference | 60 | View | |
| 2024-05-24 | PA.. |
Power of Attorney | 2 | View | |
| 2024-05-24 | FOR |
Foreign Reference | 61 | View | |
| 2024-05-24 | FOR |
Foreign Reference | 52 | View | |
| 2024-05-24 | FOR |
Foreign Reference | 146 | View | |
| 2024-05-24 | IDS |
Information Disclosure Statement (IDS) Form (SB08) | 9 | View | |
| 2022-06-09 | NTC.PUB |
Notice of Publication | 1 | View | |
| 2022-05-25 | TRAN.LET |
Transmittal Letter | 1 | View | |
| 2022-05-25 | OATH |
Oath or Declaration filed | 5 | View | |
| 2022-05-25 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2022-03-02 | N570 |
Communication - Re: Power of Attorney (PTOL-308) | 1 | View | |
| 2022-03-02 | APP.FILE.REC |
Filing Receipt | 4 | View | |
| 2022-03-02 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2022-03-02 | M327 |
Miscellaneous Communication to Applicant - No Action Count | 1 | View | |
| 2022-02-28 | REM |
Applicant Arguments/Remarks Made in an Amendment | 2 | View | |
| 2022-02-28 | WFEE |
Fee Worksheet (SB06) | 2 | View | |
| 2022-02-28 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2022-02-28 | A.PE |
Preliminary Amendment | 1 | View | |
| 2022-02-28 | CLM |
Claims | 4 | View | |
| 2022-02-03 | PA.. |
Power of Attorney | 1 | View | |
| 2022-02-03 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2022-02-03 | PA.. |
Power of Attorney | 1 | View | |
| 2021-12-02 | WCLM |
Claims Worksheet (PTO-2022) | 1 | View | |
| 2021-12-02 | APP.FILE.REC |
Filing Receipt | 4 | View | |
| 2021-12-02 | NTC.MISS.PRT |
Notice to File Missing Parts | 2 | View | |
| 2021-12-02 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2021-11-18 | SCORE |
Placeholder sheet indicating presence of supplemental content in Supplemental Complex Repository for Examiners(SCORE) | 1 | View | |
| 2021-11-18 | TRNA |
Transmittal of New Application | 1 | View | |
| 2021-11-18 | DRW.NONBW |
Drawings-other than black and white line drawings | 57 | View | |
| 2021-11-18 | ADS |
Application Data Sheet | 10 | View | |
| 2021-11-18 | N417 |
Electronic Filing System Acknowledgment Receipt | 3 | View | |
| 2021-11-18 | SPEC |
Specification | 82 | View | |
| 2021-11-18 | CLM |
Claims | 4 | View | |
| 2021-11-18 | ABST |
Abstract | 1 | View | |
| 2021-11-18 | DRW.SUPP |
Drawings-black and white line and/or other drawings | — | View |
Inventors
Lorin K. Johnson
Los Altos Hills, CA
XiaoJun Nicole Deng
San Francisco, CA
William J. Jo Siu
Emeryville, CA
Robert J. Israel
Suffern, NY
Zeev Heimanson
Calabasas, CA
Attorneys & Agents of Record
Classification
USPC
514/282
A61K31/485
A61P1/16
A61P1/00
A61P25/00
A61K9/0053
A61K31/437
A61K2300/00
Prosecution
- Examiner
- SIMMONS, CHRIS E
- Art Unit
- 1622
- Customer No.
- 193452
- Docket No.
- 134003-5034-US03
- Confirmation No.
- 5464
Publication
- Pub. No.
- US20220175764A1
- Pub. Date
- 2022-06-09
Parent
PCT
is a Continuation of
→
PCT/EP2020/065374
Filed 2020-06-03
· Non Final Action Mailed
Parent
Claims priority from a provisional application
→
App. 62/856,497
Filed 2019-06-03
· Provisional Application Expired
Parent
Claims priority from a provisional application
→
App. 62/937,606
Filed 2019-11-19
· Provisional Application Expired
U.S. PATENT SECURITY AGREEMENT
Recorded 2025-11-25
BAUSCH HEALTH COMPANIES INC.,
BAUSCH HEALTH, CANADA INC.,
BAUSCH HEALTH IRELAND LIMITED,
SOLTA MEDICAL IRELAND LIMITED
RELEASE OF SECURITY INTEREST
Recorded 2025-11-20
SOLTA MEDICAL, INC.,
PRECISION DERMATOLOGY, INC.,
BAUSCH HEALTH IRELAND LIMITED (F/K/A/ VALEANT PHARMACEUTICALS IRELAND LIMITED),
SALIX PHARMACEUTICALS, INC.,
SALIX PHARMACEUTICALS, LTD,
SANTARUS, INC.,
MEDICIS PHARMACEUTICAL CORPORATION,
HUMAX PHARMACEUTICAL S.A.,
SOLTA MEDICAL IRELAND LIMITED,
BAUSCH & LOMB MEXICO, S.A. DE C.V.,
BAUSCH+LOMB OPS B.V.,
BAUSCH HEALTH AMERICAS, INC.,
BAUSCH HEALTH COMPANIES INC.,
BAUSCH HEALTH HOLDCO LIMITED,
BAUSCH HEALTH MAGYARORSZAG KFT (A/K/A BAUSCH HEALTH HUNGARY LLC),
BAUSCH HEALTH POLAND SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA (F/K/A VALEANT PHARMA POLAND SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA),
BAUSCH HEALTH US, LLC,
BAUSCH HEALTH, CANADA INC. / SANTE BAUSCH, CANADA INC.,
ICN POLFA RZESZOW SPOLKA AKCYJNA (A/K/A ICN POLFA RZESZOW S.A.),
ORAPHARMA, INC.,
PRZEDSIEBIORSTWO FARMACEUTYCZNE JELFA SPOLKA AKCYJNA (A/K/A PRZEDSIEBIORSTWO FARMACEUTYCZNE JELFA S.A.),
SOLTA MEDICAL DUTCH HOLDINGS B.V.,
V-BAC HOLDING CORP.,
VRX HOLDCO LLC,
1261229 B.C. LTD.,
1530065 B.C. LTD.
RELEASE OF SECURITY INTEREST
Recorded 2025-04-08
SECURITY AGREEMENT (FIRST LIEN)
Recorded 2022-11-04
SECURITY AGREEMENT (SECOND LIEN)
Recorded 2022-11-04
from
BAUSCH HEALTH AMERICAS, INC.,
BAUSCH HEALTH US, LLC,
MEDICIS PHARMACEUTICAL CORPORATION,
ORAPHARMA, INC.,
PRECISION DERMATOLOGY, INC.,
SALIX PHARMACEUTICALS, INC.,
SALIX PHARMACEUTICALS, LTD.,
SANTARUS, INC.,
SOLTA MEDICAL, INC.
SECURITY AGREEMENT (SECOND LIEN)
Recorded 2022-10-05
from
BAUSCH HEALTH AMERICAS, INC.,
BAUSCH HEALTH US, LLC,
MEDICIS PHARMACEUTICAL CORPORATION,
ORAPHARMA, INC.,
PRECISION DERMATOLOGY, INC.,
SALIX PHARMACEUTICALS, INC.,
SALIX PHARMACEUTICALS, LTD.,
SANTARUS, INC.,
SOLTA MEDICAL, INC.
SECURITY AGREEMENT (FIRST LIEN)
Recorded 2022-10-04
SECURITY INTEREST
Recorded 2022-07-07
SECURITY INTEREST
Recorded 2022-07-07
from
BAUSCH HEALTH COMPANIES INC.,
BAUSCH HEALTH IRELAND LIMITED,
BAUSCH HEALTH, CANADA INC.,
SOLTA MEDICAL IRELAND LIMITED
SECURITY INTEREST
Recorded 2022-06-13
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded 2022-02-08
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded 2022-02-08
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded 2022-02-08
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Quick Facts
- App. No.
- 17/529,818
- Filed
- 2021-11-18
- Pub. No.
- US20220175764A1
- Examiner
- SIMMONS, CHRIS E
- Art Unit
- 1622
External Links