Integrated device for temporal binning of received photons
An integrated circuit includes a photodetection region configured to receive incident photons. The photodetection region is configured to produce a plurality of charge carriers in response to the incident photons. The integrated circuit also includes at least one charge carrier storage region. The integrated circuit also includes a charge carrier segregation structure configured to selectively direct charge carriers of the plurality of charge carriers into the at least one charge carrier storage region based upon times at which the charge carriers are produced.
1. An integrated circuit, comprising:
a photodetection region configured to receive incident photons, the photodetection region being configured to produce a plurality of charge carriers in response to the incident photons;
at least one charge carrier storage region; and
a charge carrier segregation structure configured to selectively direct charge carriers of the plurality of charge carriers into the at least one charge carrier storage region based upon times at which the plurality of charge carriers are produced,
wherein the integrated circuit further comprises a semiconductor material with a graded doping concentration to establish a lateral electric field for driving the plurality of charge carriers toward the at least one charge carrier storage region,
wherein the charge carrier segregation structure is configured to aggregate, in the at least one charge carrier storage region, charge carriers of the plurality of charge carriers produced in response to a plurality of respective excitation light pulses.
2. The integrated circuit of claim 1 , wherein the at least one charge carrier storage region comprises a plurality of charge carrier storage regions, and wherein the charge carrier segregation structure is configured to selectively direct sensed charge carriers into respective charge carrier storage regions of the plurality of charge carrier storage regions based on times which the sensed charge carriers are generated in the photodetection region.
3. The integrated circuit of claim 1 , wherein the integrated circuit is configured to:
(i) analyze one or more signals from the at least one charge carrier storage region to produce information regarding arrival of photons over time;
(ii) transmit information regarding one or more signals from the at least one charge carrier storage region to a computing device for analysis; or
perform both (i) and (ii).
4. The integrated circuit of claim 3 , wherein the integrated circuit or the computing device is configured to analyze the one or more signals to calculate a luminance lifetime or discriminate a first luminance lifetime from a second luminance lifetime.
5. The integrated circuit of claim 4 , wherein the integrated circuit or the computing device is configured to analyze the one or more signals to calculate a fluorescence lifetime or discriminate a first fluorescence lifetime from a second fluorescence lifetime.
6. The integrated circuit of claim 1 , wherein the integrated circuit is configured to detect the photons to sequence a biological molecule.
7. The integrated circuit of claim 1 , wherein the integrated circuit is configured to receive the incident photons from fluorophores.