IP Library › Granted Patent US 12,207,652
Granted Patent B2
US 12,207,652 · App. 17/533,717 · Granted Jan 28, 2025

Copper-based antimicrobial PVD coatings with wear indicator

Inventors: Bryce Randolph Anton (Longmont, CO); Nicholas Peterson (Arvada, CO)
Assignee: Vapor Technologies, Inc.
A01N25/34A01N59/00A01N59/16A01N59/20
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 12,207,652
App. No.
17/533,717
Granted
Jan 28, 2025
Kind
B2
Abstract

A bioactive coated substrate includes a base substrate, an indicator layer disposed over the base substrate, and a bioactive layer disposed on the indicator layer. Characteristically, the indicator layer has color sufficiently different from the bioactive layer to be visually perceived by a user when the bioactive layer wears away.

Claims (30)

1. A bioactive coated substrate comprising:

a base substrate;

an indicator layer disposed over the base substrate; and

a bioactive layer disposed on the indicator layer where the indicator layer has color sufficiently different from the bioactive layer to be visually perceived by a user when the bioactive layer wears away, the bioactive layer being composed of a component selected from the group consisting of bioactive metals, bioactive metal alloys, bioactive metal-containing compounds, and combinations thereof, wherein the indicator layer is composed of zirconium carbonitride, zirconium nitride, zirconium oxycarbide, zirconium oxynitride, zirconium oxycarbonitride, titanium nitride, or diamond like carbon and wherein the bioactive layer is a top layer, wherein the bioactive layer has a thickness from about 50 to 1500 nm and the indicator layer has a thickness from 20 to 300 nm.

2. The bioactive coated substrate of claim 1 , wherein the bioactive layer is composed of a component selected from the group consisting of copper metal, copper oxides, copper nitrides, copper oxides containing carbon atoms, and combinations thereof.

3. The bioactive coated substrate of claim 1 , wherein the bioactive layer is composed of a component selected from the group consisting of copper metal, copper alloy, copper oxides, copper nitrides, copper oxides containing carbon atoms, and combinations thereof.

4. The bioactive coated substrate of claim 1 wherein the bioactive layer is composed of a component selected from the group consisting of include copper alloys, copper-containing compounds, and combinations thereof.

5. The bioactive coated substrate of claim 1 wherein the bioactive layer is composed of a mixture of a copper metal alloy and a component selected from the group consisting of zirconium nitride, titanium nitride, zirconium oxycarbides, zirconium oxides, diamond-like-carbon, and combinations thereof.

6. The bioactive coated substrate of claim 1 wherein the indicator layer is composed of zirconium carbonitride, zirconium nitride, zirconium oxycarbide, zirconium oxynitride, zirconium oxycarbonitride, or diamond like carbon.

7. The bioactive coated substrate of claim 1 , wherein the bioactive layer is composed of CuO x , where x is from 0.6 to 1.2.

8. The bioactive coated substrate of claim 1 , wherein the bioactive layer is composed of CuO a N b , where a is from 0.0 to 1.2 and b, is from 0.01 to 0.4.

9. The bioactive coated substrate of claim 1 , wherein the bioactive layer is composed of CuO c C d , where c is from 0.0 to 1.2 and d, is from 0.01 to 0.4.

10. The bioactive coated substrate of claim 1 , wherein at least one of Lab color space coordinates L*, a*, and b* relative to CIE standard illuminant D50 of the bioactive layer differs from that of the indicator layer by at least 5%.

11. The bioactive coated substrate of claim 1 , wherein each of Lab color space coordinates L*, a*, and b* relative to CIE standard illuminant D50 of the bioactive layer differs from those of the indicator layer by at least 5%.

12. The bioactive coated substrate of claim 1 , wherein delta E for the bioactive layer and the indicator layer is greater than or equal to 2.0.

13. The bioactive coated substrate of claim 1 , wherein delta E for the bioactive layer and the indicator layer is greater than or equal to 5.0.

14. A bioactive coated substrate comprising:

a base substrate;

a base layer disposed over the base substrate; and

a plurality of alternating bioactive layers and interlayers disposed over the base layer, wherein the base layer and/or at least one of the interlayers is an indicator layer that has a color sufficiently different from the bioactive layers to be visually perceived by a user when one or more of the bioactive layers wears away, each bioactive layer being composed of a component selected from the group consisting of bioactive metals, bioactive metal alloys, bioactive metal-containing compounds, and combinations thereof, wherein the base layer and each interlayer is composed of zirconium carbonitride, zirconium nitride, zirconium oxycarbide, zirconium oxynitride, zirconium oxycarbonitride, titanium nitride, or diamond like carbon and wherein one of the bioactive layers is a top layer, wherein each bioactive layer has a thickness from about 50 to 1500 nm, each interlayer has a thickness from 20 to 300 nm, and the base layer has a thickness from 20 to 300 nm.

15. The bioactive coated substrate of claim 14 , wherein each bioactive layer is composed of a component selected from the group consisting of copper metal, copper alloy, copper oxides, copper nitrides, copper oxides containing carbon atoms, and combinations thereof.

16. The bioactive coated substrate of claim 14 , wherein the base layer and each interlayer is composed of zirconium carbonitride, zirconium nitride, zirconium oxycarbide, zirconium oxynitride, zirconium oxycarbonitride, or diamond like carbon.

17. The bioactive coated substrate of claim 14 , wherein at least one of Lab color space coordinates L*, a*, and b* relative to CIE standard illuminant D50 of an outermost bioactive layer differs from that of the indicator layer by at least 5%.

18. The bioactive coated substrate of claim 14 , wherein each of Lab color space coordinates L*, a*, and b* relative to CIE standard illuminant D50 of an outermost bioactive layer differs from those of the indicator layer by at least 5%.

19. The bioactive coated substrate of claim 14 , wherein delta E for an outermost bioactive layer and the indicator layer is greater than or equal to 2.0.

20. The bioactive coated substrate of claim 14 , wherein delta E for an outermost bioactive layer and the indicator layer is greater than or equal to 5.0.

21. A bioactive coated substrate comprising:

a base substrate;

an indicator layer disposed over the base substrate; and

a bioactive layer disposed on the indicator layer where the indicator layer has color sufficiently different from the bioactive layer to be visually perceived by a user when the bioactive layer wears away, the bioactive layer being composed of CuO c C d , where c is from 0.0 to 1.2 and d is from 0.01 to 0.4, wherein the indicator layer is composed of zirconium carbonitride, zirconium nitride, zirconium oxycarbide, zirconium oxynitride, zirconium oxycarbonitride, titanium nitride, or diamond like carbon and wherein the bioactive layer is a top layer.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 10, 2022
From: ANTON, BRYCE RANDOLPH; PETERSON, NICHOLAS
To: VAPOR TECHNOLOGIES, INC.
Reel/Frame 058592/0469 →
Continuity (2)
Provisional Application 63122240 · Dec 7, 2020
Related Publication 20220174946A1 · Jun 9, 2022
References Cited (39)
US 5454886A · Burrell et al. · 1995 [cited by applicant]
US 5681575A · Burrell et al. · 1997 [cited by applicant]
US 5753251A · Burrell et al. · 1998 [cited by applicant]
US 5770255A · Burrell et al. · 1998 [cited by applicant]
US 5958440A · Burrell et al. · 1999 [cited by applicant]
US 6238686B1 · Burrell et al. · 2001 [cited by applicant]
US 8066854B2 · Storey et al. · 2011 [cited by applicant]
US 8530056B2 · Pilloy et al. · 2013 [cited by applicant]
US 9107981B2 · Neumann et al. · 2015 [cited by applicant]
US 20060240067A1 · Gillis · 2006 [cited by examiner]
US 20070203574A1 · McGrath · 2007 [cited by examiner]
US 20090162695A1 · Hevesi et al. · 2009 [cited by applicant]
US 20090198343A1 · Spain et al. · 2009 [cited by applicant]
US 20120094097A1 · Chang · 2012 [cited by examiner]
US 20120244381A1 · Chang · 2012 [cited by examiner]
US 20130252021A1 · Neumann · 2013 [cited by examiner]
US 20150361278A1 · Call · 2015 [cited by examiner]
CN 108070829A · 2018 [cited by applicant]
DE 102012109272A1 · 2014 [cited by examiner]
EP 2202330A1 · 2010 [cited by applicant]
EP 3004009B1 · 2019 [cited by applicant]
EP 3587616A2 · 2020 [cited by applicant]
WO WO2022027077A1 · 2022 [cited by examiner]
Li, Q., Zhao, M., Li, L., Dong, L., Wu, J., & Li, D. (May 2020). Co-regulation of Cu/Zn contents enhanced the biological and mechanical properties of TiN coated Ti-6Al-4V alloy. Surface and Coatings Technology, 395, 125… [cited by examiner]
Techkon USA, A simple review of Cie δE* (Color Differenc) Equations, Sep. 11, 2018, https://techkonusa.com/a-simple-review-of-cie-Åe-color-difference-equations/ (Year: 2018). [cited by examiner]
Espacenet Translation of DE-102012109272-A1 (Year: 2023). [cited by examiner]
Espacenet Translation of WO-2022027077-A1 (Year: 2023). [cited by examiner]
Kumar, D. Dinesh, and Gobi Saravanan Kaliaraj. “Multifunctional zirconium nitride/copper multilayer coatings on medical grade 316L SS and titanium substrates for biomedical applications.” Journal of the Mechanical Behav… [cited by examiner]
Borsa, D.M. et al. “Growth and properties of Cu3N films and Cu3N/ [gamma] -Fe4N bilayers,” Applied Physics Letters (2002), v. 80, n. 10, pp. 1823-1825. [cited by applicant]
Chen, N-H et al., “Antimicrobial and Decorative Ion-Plated Copper-Containing Ceramic Coatings,” Surface and Coatings Technology, v. 236, 12, (2013), pp. 29-35. [cited by applicant]
Chu, J.P. et al., “Sputter-deposited Cu/Cu(O) multilayers exhibiting enhanced strength and tunable modulus,” ACTA Materialia, v. 58, n. 19, (2010), p. 6374. [cited by applicant]
Robertson, S.N. et al., “Investigation of the antimicrobial properties of modified multilayer diamond-like carbon coatings on 316 stainless steel,” Surface and Coatings Technology (2016), v. 314, pp. 72-78. [cited by applicant]
Vishwakarma V. et al., “Bacterial Adhesion and Hemocompatability Behavior of TiN, TiO2 Single and TiN/TiO2 Multilayer Coated 316L Ss for Bioimplants,” J. of Biometrics, Biomaterials and Biomedical Engineering Trans Tech… [cited by applicant]
Extended Search Report dtd Jun. 20, 2022 for EP Appn. No. 21212825, 18 pgs. [cited by applicant]
He, X. et al., “Biocompatibility, Corrosion Resistances and Antibacterial Activity of TiO2/CuO Coating on Titanium,” Ceramics Int'l, (2017), v. 43, n. 18, p. 16185-16195. [cited by applicant]
Partial Search Report & Written Opinion dated Apr. 28, 2022 for EP Appn. No. 21 21 2825, 16 pgs. [cited by applicant]
Office Action dated Sep. 21, 2023 for Chinese Appn. No. 202111483507.3 filed Dec. 7, 2021, 9 pgs. (no English translation). [cited by applicant]
Parvizi, J. et al., “Antibacterial Coatings and Antibacterial Materials,” Prosthetic Joint Infection Clinical Practices and Considerations, 2020, p. 303 (English translation)—3 pgs total. [cited by applicant]
Third Office Action dated Jun. 12, 2024 for CN Appn. No. 202111483507.3 and English Translation, 12 pgs. [cited by applicant]