IP Library Granted Patent US 12,533,177
Granted Patent B2
US 12,533,177 · App. 17/542,176 · Granted Jan 27, 2026

Methods and systems for real-time planning and monitoring of ablation needle deployment in tissue

Inventors: Jiayu Chen (Palo Alto, CA); Hyeonsoo Chang (Palo Alto, CA); Edmond Ming Wai Chiu (San Francisco, CA); Amer Hammudi (Tracy, CA); Harry Kwan (San Francisco, CA); Michael A. Munrow (Belmont, CA)
Assignee: Gynesonics, Inc.
A61B18/1477A61B18/18A61B18/1815A61B90/37A61B8/0841A61B2018/00208A61B2018/00577A61B18/02A61B18/042A61B2018/1425A61B2018/1475A61B34/10A61B2090/0811A61B90/36A61B2090/363A61B2090/378
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 12,533,177
App. No.
17/542,176
Granted
Jan 27, 2026
Kind
B2
Abstract

A control handle of a treatment probe is manipulated to advance and/or deploy one or more treatment structures into tissue. The treatment probe is coupled to a display to show an image field including target tissue for treatment. Virtual treatment and safety boundaries are overlaid over the image field. The boundaries include virtual stop positions for the needle and tines. A joystick or directional pad on the probe handle, operable independently from the user interface to advance and/or deploy the one or more treatment structures, can be manipulated to adjust the size and/or position of these boundaries. Sensors within the probe detect the real-time position of the one or more treatment structures, and the sensed positions are displayed in real-time. The user can observe the display to deploy the one or more treatment structures to the displayed virtual stop positions.

Claims (24)

1 . A system for treating an anatomical feature in tissue, said system comprising:

a treatment probe comprising a handle, a probe body, and a treatment structure deployable from the probe body to treat the anatomical feature; and

a real-time display coupled to the probe and configured to display a real time image and project the deployed treatment structure and at least one of a treatment region or a safety region on the real time image,

wherein the handle comprises a controller configured to be physically manipulated for adjusting a parameter of one or more boundaries of the at least one of the treatment region or safety region, and

wherein the controller is further configured to be physically manipulated for adjusting a power delivery parameter of the treatment probe, adjusting a display parameter of the real-time display, or deploying the treatment structure, without adjusting any parameter of the one or more boundaries of the at least one of the treatment region or safety region.

2 . A system as in claim 1 , wherein the treatment structure comprises a needle structure.

3 . A system as in claim 2 , wherein the probe further comprises a plurality of tines deployable from the needle structure.

4 . A system as in claim 1 , wherein the adjustment of the display parameter of the real-time display by the physical manipulation of the controller is to one or more of access, navigate, or display menu items on the real-time display.

5 . A system of claim 1 , wherein the adjustment of the display parameter of the real-time display by the physical manipulation of the controller is to access one or more information sources on the real-time display.

6 . A system as in claim 1 , wherein the controller is configured to be physically manipulated for adjusting the power delivery parameter of the treatment probe without adjusting the any parameter of the one or more boundaries.

7 . A system of claim 6 , wherein the power delivery parameter is a time length for power delivery.

8 . A system of claim 1 , wherein the controller is further configured to be physically manipulated for adjusting the display parameter of the real-time display without adjusting the any parameter of the one or more boundaries.

9 . A system as in claim 8 , wherein the treatment structure comprises a needle structure, wherein the probe further comprises a plurality of tines deployable from the needle structure, the real-time display is configured to show one or more virtual tine stop indicators for the plurality of tines, and the adjustment of the display parameter of the real-time display by the physical manipulation of the controller is to re-position the one or more virtual stop indicators.

10 . A system of claim 8 , wherein the adjustment of the display parameter of the real-time display by the physical manipulation of the controller is to mark, identify, and/or document a region of interest.

11 . A system of claim 1 , wherein the controller is configured to be physically manipulated for deploying the treatment structure without adjusting the any parameter of the one or more boundaries.

12 . A system of claim 11 , wherein the probe comprises a servo to drive the treatment structure, and wherein deploying the treatment structure controlled by the physical manipulation of the controller is to operate the servo to drive the treatment structure.

13 . A system of claim 1 , wherein the parameter of the one or more boundaries adjusted by the physical manipulation of the controller comprises a size of the one or more boundaries.

14 . A system of claim 1 , wherein the parameter of the one or more boundaries adjusted by the physical manipulation of the controller comprises a position of the one or more boundaries.

15 . A system of claim 14 , wherein the controller is further configured to be physically manipulated for adjusting a size of the one or more boundaries.

16 . A system as in claim 15 , wherein the controller comprises a joystick or directional pad on the handle of the treatment probe.

17 . A system as in claim 16 , wherein the joystick or directional pad is configured to be pushed in a first direction to enlarge the one or more boundaries, and wherein the joystick or directional pad is configured to be pushed in a second direction opposite the first direction to shrink the one or more boundaries.

18 . A system as in claim 17 , wherein the joystick or directional pad is configured to be pushed in a third direction to advance the one or more boundaries, and wherein the joystick or directional pad is configured to be pushed in a fourth direction opposite the third direction to retract the one or more boundaries.

19 . A system of claim 18 , wherein the joystick or direction pad is configured to be rotated for adjusting the power delivery parameter of the treatment probe, adjusting the display parameter of the real-time display, or deploying the treatment structure, without adjusting the any parameter of the one or more boundaries.

20 . A system of claim 18 , wherein the joystick or direction pad is configured to be depressed for adjusting the power delivery parameter of the treatment probe, adjusting the display parameter of the real-time display, or deploying the treatment structure, without adjusting the any parameter of the one or more boundaries.

Assignments (4)
RELEASE OF SECURITY INTEREST RECORDED AT REEL/FRAME 070236/0154 Recorded Apr 24, 2026
From: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
To: GYNESONICS, INC.
Reel/Frame 075455/0789 →
SECURITY INTEREST Recorded Apr 8, 2026
From: BIOTHERANOSTICS, INC.; GEN-PROBE INCORPORATED; GEN-PROBE PRODESSE, INC.; CYTYC CORPORATION; SUROS SURGICAL SYSTEMS, INC.; GYNESONICS, INC.; BOLDER SURGICAL, LLC; FAXITRON BIOPTICS, LLC; HEALTH BEACONS, INC.; HOLOGIC, INC.
To: ROYAL BANK OF CANADA, AS COLLATERAL AGENT
Reel/Frame 075462/0440 →
SECURITY INTEREST Recorded Feb 14, 2025
From: GYNESONICS, INC.
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 070236/0154 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 3, 2021
From: CHEN, JIAYU; CHANG, HYEONSOO; CHIU, EDMOND MING WAI; HAMMUDI, AMER; KWAN, HARRY; MUNROW, MICHAEL A.
To: GYNESONICS, INC.
Reel/Frame 058302/0877 →
Continuity (3)
Division 15811520 · Nov 13, 2017
Provisional Application 62421669 · Nov 14, 2016
Related Publication 20220287763A1 · Sep 15, 2022
References Cited (105)
US 6050992A · Nichols · 2000 [cited by applicant]
US 6540677B1 · Angelsen et al. · 2003 [cited by applicant]
US 6623481B1 · Garbagnati et al. · 2003 [cited by applicant]
US 6936048B2 · Hurst · 2005 [cited by applicant]
US 6944490B1 · Chow · 2005 [cited by applicant]
US 6969354B1 · Marian · 2005 [cited by applicant]
US 7160296B2 · Pearson et al. · 2007 [cited by applicant]
US 7229401B2 · Kindlein · 2007 [cited by applicant]
US 7387628B1 · Behl et al. · 2008 [cited by applicant]
US 7517346B2 · Sloan et al. · 2009 [cited by applicant]
US 7815571B2 · Deckman et al. · 2010 [cited by applicant]
US 7874986B2 · Deckman et al. · 2011 [cited by applicant]
US 7918795B2 · Grossman · 2011 [cited by applicant]
US 7963941B2 · Wilk · 2011 [cited by applicant]
US 8080009B2 · Lee et al. · 2011 [cited by applicant]
US 8088072B2 · Munrow et al. · 2012 [cited by applicant]
US 8157741B2 · Hirota · 2012 [cited by applicant]
US 8157745B2 · Schoot · 2012 [cited by applicant]
US 8206300B2 · Deckman et al. · 2012 [cited by applicant]
US 8216231B2 · Behl et al. · 2012 [cited by applicant]
US 8221321B2 · Mcmorrow et al. · 2012 [cited by applicant]
US 8262574B2 · Placek et al. · 2012 [cited by applicant]
US 8262577B2 · Munrow et al. · 2012 [cited by applicant]
US 8287485B2 · Kimura et al. · 2012 [cited by applicant]
US 8377041B2 · Frassica et al. · 2013 [cited by applicant]
US 8469893B2 · Chiang et al. · 2013 [cited by applicant]
US 8512330B2 · Epstein et al. · 2013 [cited by applicant]
US 8512333B2 · Epstein et al. · 2013 [cited by applicant]
US 8540634B2 · Bruce et al. · 2013 [cited by applicant]
US 8585598B2 · Razzaque et al. · 2013 [cited by applicant]
US 8622911B2 · Hossack et al. · 2014 [cited by applicant]
US 8663130B2 · Neubach et al. · 2014 [cited by applicant]
US 8718339B2 · Tonomura et al. · 2014 [cited by applicant]
US 8814796B2 · Martin et al. · 2014 [cited by applicant]
US 8992427B2 · Munrow et al. · 2015 [cited by applicant]
US 9089287B2 · Sliwa et al. · 2015 [cited by applicant]
US 9198707B2 · Mckay et al. · 2015 [cited by applicant]
US 9198719B2 · Murdeshwar et al. · 2015 [cited by applicant]
US 9247925B2 · Havel et al. · 2016 [cited by applicant]
US 9439627B2 · Case et al. · 2016 [cited by applicant]
US 9510898B2 · Epstein et al. · 2016 [cited by applicant]
US 9516996B2 · Diolaiti et al. · 2016 [cited by applicant]
US 9861336B2 · Munrow et al. · 2018 [cited by applicant]
US 10321951B2 · Placek et al. · 2019 [cited by applicant]
US 10595819B2 · Deckman et al. · 2020 [cited by applicant]
US 10610197B2 · Deckman et al. · 2020 [cited by applicant]
US 11219483B2 · Chen et al. · 2022 [cited by applicant]
US 20070006215A1 · Epstein et al. · 2007 [cited by applicant]
US 20070179380A1 · Grossman · 2007 [cited by applicant]
US 20070249939A1 · Gerbi et al. · 2007 [cited by applicant]
US 20080033493A1 · Deckman et al. · 2008 [cited by applicant]
US 20080228081A1 · Becker et al. · 2008 [cited by applicant]
US 20090043295A1 · Arnal et al. · 2009 [cited by applicant]
US 20090099544A1 · Munrow et al. · 2009 [cited by applicant]
US 20090131790A1 · Munrow et al. · 2009 [cited by applicant]
US 20090287081A1 · Grossman et al. · 2009 [cited by applicant]
US 20100056926A1 · Deckman et al. · 2010 [cited by applicant]
US 20100262133A1 · Hoey et al. · 2010 [cited by applicant]
US 20120035474A1 · Deckman et al. · 2012 [cited by applicant]
US 20120071794A1 · Karni · 2012 [cited by applicant]
US 20120165813A1 · Lee et al. · 2012 [cited by applicant]
US 20120209115A1 · Tonomura · 2012 [cited by applicant]
US 20120277737A1 · Curley · 2012 [cited by applicant]
US 20120316440A1 · Munrow et al. · 2012 [cited by applicant]
US 20130281863A1 · Chiang et al. · 2013 [cited by applicant]
US 20130317366A1 · Hirayama et al. · 2013 [cited by applicant]
US 20140073910A1 · Munrow et al. · 2014 [cited by applicant]
US 20140180273A1 · Nair · 2014 [cited by applicant]
US 20140276081A1 · Tegels · 2014 [cited by applicant]
US 20150150497A1 · Goldchmit · 2015 [cited by applicant]
US 20150173592A1 · Leeflang et al. · 2015 [cited by applicant]
US 20150257779A1 · Sinelnikov et al. · 2015 [cited by applicant]
US 20160151041A1 · Lee et al. · 2016 [cited by applicant]
US 20160278740A1 · Negrila et al. · 2016 [cited by applicant]
US 20160310042A1 · Kesten et al. · 2016 [cited by applicant]
CN 103379853A · 2013 [cited by applicant]
CN 105007815A · 2015 [cited by applicant]
EP 0805595 · 1997 [cited by applicant]
EP 2207078 · 2010 [cited by applicant]
JP 9298741 · 1997 [cited by applicant]
JP H11508790A · 1999 [cited by applicant]
JP 2001340350A · 2001 [cited by applicant]
JP 2006513831A · 2006 [cited by applicant]
JP 2007215672A · 2007 [cited by applicant]
JP 2011500164A · 2011 [cited by applicant]
JP WO2009044670 · 2011 [cited by applicant]
JP 2015528114A · 2015 [cited by applicant]
JP 2015529114 · 2015 [cited by applicant]
JP 2019524870 · 2019 [cited by applicant]
WO WO2009049082A1 · 2009 [cited by applicant]
WO WO2014039795A1 · 2014 [cited by applicant]
WO WO2018089923A1 · 2018 [cited by applicant]
EP17870152.0 Extended European Search Report dated Sep. 30, 2019. [cited by applicant]
International Search Report and Written Opinion dated Jan. 17, 2018 for International PCT Patent Application No. PCT/US2017/061366. [cited by applicant]
U.S. Appl. No. 15/811,520 Office Action dated Aug. 25, 2021. [cited by applicant]
U.S. Appl. No. 15/811,520 Office Action dated Feb. 26, 2021. [cited by applicant]
U.S. Appl. No. 15/811,520 Notice of Allowance dated Sep. 14, 2021. [cited by applicant]
CN Serial No. 2017800806556 Office Action dated Nov. 28, 2022. [cited by applicant]
JP Serial No. 2019-524870 Office Action dated Oct. 20, 2021. [cited by applicant]
JP Serial No. 2022-063288 Final Office Action dated Nov. 2, 2023. [cited by applicant]
JP Serial No. 2022-063288 Office Action dated Feb. 13, 2023. [cited by applicant]
PCT/US2017/061366 International Preliminary Report on Patentability dated May 14, 2019. [cited by applicant]
Foreign OA for JP Patent Appln. No. 2022-63288 dated May 1, 2025 (with English translation). [cited by applicant]
EP23178101.4 Extended European Search Report dated Nov. 21, 2023. [cited by applicant]
Foreign OA for JP Patent Appln. No. 2024-32047 dated Oct. 1, 2025 (with English translation). [cited by applicant]