IP Library › Granted Patent US 12,274,620
Granted Patent B2
US 12,274,620 · App. 17/549,580 · Granted Apr 15, 2025

Implant having multiple adjusting mechanisms

Inventors: Eran Miller (Moshav Beit Elazari, IL); Tal Reich (Moledet, IL); Amir Gross (Tel Aviv-Jaffa, IL); Tal Sheps (Givat Shmuel, IL); Oz Cabiri (Hod Hasharon, IL)
Assignee: Edwards Lifesciences Innovation (Israel) Ltd.
A61F2/2445A61F2/2448A61F2/2466A61F2/2454A61F2/2457A61F2250/001
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Quick Facts
Patent No.
US 12,274,620
App. No.
17/549,580
Granted
Apr 15, 2025
Kind
B2
Abstract

An implant structure, comprises a body portion, a first adjusting mechanism, and a second adjusting mechanism. The body portion is configured to be secured within a heart of a patient. The first adjusting mechanism is coupled to a first portion of the body portion, and comprises a first ring that surrounds the first portion and is moveable with respect to the body portion. The second adjusting mechanism is coupled to a second portion of the body portion, and comprises a second ring that surrounds the second portion and is moveable with respect to the body portion. A first elongate tool is configured to remodel tissue of the heart by actuating the first adjusting mechanism. A second elongate tool is configured to remodel tissue of the heart by actuating the second adjusting mechanism.

Claims (67)

1. Apparatus for use at an atrium of a heart of a patient, the apparatus comprising:

an implant structure, comprising:

a body portion, configured to be secured within the atrium;

a first adjusting mechanism, coupled to a first portion of the body portion, and comprising a first ring that surrounds the first portion and is moveable with respect to the body portion; and

a second adjusting mechanism, coupled to a second portion of the body portion, and comprising a second ring that surrounds the second portion, and is moveable with respect to the body portion;

a first elongate tool, configured to remodel tissue of the heart by actuating the first adjusting mechanism; and

a second elongate tool, configured to remodel tissue of the heart by actuating the second adjusting mechanism.

2. The apparatus according to claim 1 , wherein the first tool and the second tool are transluminally advanceable to the implant structure after the body portion has been secured within the atrium.

3. The apparatus according to claim 1 , further comprising:

a first longitudinal guide member, a distal end thereof coupled to the first adjusting mechanism, the first tool being advanceable along the first guide member to the first adjustment mechanism; and

a second longitudinal guide member, a distal end thereof coupled to the second adjustment mechanism, the second tool being advanceable along the second guide member to the second adjustment mechanism.

4. The apparatus according to claim 1 , wherein:

the first tool is configured to actuate the first adjusting mechanism by applying a rotational force to the first adjusting mechanism, and

the second tool is configured to actuate the second adjusting mechanism by applying a rotational force to the second adjusting mechanism.

5. The apparatus according to claim 1 , wherein the implant structure is configured to be transluminally advanced toward the heart.

6. The apparatus according to claim 1 , wherein the tool is configured to actuate the first adjusting mechanism and the second adjusting mechanism while the heart is beating.

7. The apparatus according to claim 1 , wherein each of the adjusting mechanisms comprises a locking mechanism:

having an unlocked state in which the adjusting mechanism is adjustable,

having a locked state in which the locking mechanism inhibits adjustment of the adjusting mechanism, and

configured to be intracorporeally moved between the locked state and the unlocked state.

8. The apparatus according to claim 1 , wherein the first adjusting mechanism and the second adjusting mechanism are both rotatable bidirectionally.

9. The apparatus according to claim 1 , wherein the implant structure comprises an annulus ring, configured to be secured to an annulus of a valve of the heart.

10. A method for use at an atrium of a heart of a patient, the method comprising:

securing, within the atrium, a body portion of an implant structure, the implant structure including:

a first adjusting mechanism that includes a first ring that (i) surrounds a first portion of the body portion, and (ii) is moveable with respect to the body portion, and

a second adjusting mechanism that includes a second ring that (i) surrounds a second portion of the body portion, and (ii) is moveable with respect to the body portion; and

remodeling tissue of the heart by:

using a first elongate tool to intracorporeally actuate the first adjusting mechanism, and

using a second elongate tool to intracorporeally actuate the second adjusting mechanism.

11. The method according to claim 10 , further comprising transluminally advancing the first tool and the second tool to the implant structure after the body portion has been secured within the atrium.

12. The method according to claim 10 , further comprising:

transluminally advancing the first tool along a first guide member to the first adjustment mechanism while a distal end of the first guide member is coupled to the first adjustment mechanism; and

transluminally advancing the second tool along a second guide member to the second adjustment mechanism while a distal end of the second guide member is coupled to the second adjustment mechanism.

13. The method according to claim 10 , wherein:

using the first elongate tool to actuate the first adjusting mechanism comprises using the first elongate tool to apply a rotational force to the first adjustment mechanism, and

using the second elongate tool to actuate the second adjusting mechanism comprises using the second elongate tool to apply a rotational force to the second adjustment mechanism.

14. The method according to claim 10 , wherein securing the body portion within the atrium comprises securing the body portion within the atrium via an open-heart procedure.

15. The method according to claim 10 , securing the body portion within the atrium heart comprises securing the body portion within the atrium heart via a transluminal procedure.

16. The method according to claim 10 , wherein:

using the first elongate tool to actuate the first adjusting mechanism comprises using the first elongate tool to actuate the first adjusting mechanism while the heart is beating, and

using the second elongate tool to actuate the second adjusting mechanism comprises using the second elongate tool to actuate the second adjusting mechanism while the heart is beating.

17. The method according to claim 10 , wherein each of the adjusting mechanisms includes a locking mechanism, and wherein the method further comprises:

using the first tool to intracorporeally transition the locking mechanism of the first adjustment mechanism between a locked state and an unlocked state; and

using the second tool to intracorporeally transition the locking mechanism of the second adjustment mechanism between a locked state and an unlocked state.

18. The method according to claim 10 , wherein the implant structure includes an annulus ring, and wherein securing the body portion within the heart comprises securing the annulus ring to an annulus of a valve of the heart.

19. Apparatus for use at a heart of a patient, the apparatus comprising:

an implant structure, comprising:

an annulus ring, configured to be secured to an annulus of a valve of the heart;

a first adjusting mechanism, coupled to a first portion of the annulus ring, and comprising a first ring that surrounds the first portion and is moveable with respect to the annulus ring; and

a second adjusting mechanism, coupled to a second portion of the annulus ring, and comprising a second ring that surrounds the second portion, and is moveable with respect to the annulus ring;

a first elongate tool, configured to remodel tissue of the heart by actuating the first adjusting mechanism; and

a second elongate tool, configured to remodel tissue of the heart by actuating the second adjusting mechanism.

20. A method for use at a heart of a patient, the method comprising:

securing, to an annulus of a valve of the heart, an annulus ring of an implant structure, the implant structure including:

a first adjusting mechanism that includes a first ring that (i) surrounds a first portion of the annulus ring, and (ii) is moveable with respect to the annulus ring, and

a second adjusting mechanism that includes a second ring that (i) surrounds a second portion of the annulus ring, and (ii) is moveable with respect to the annulus ring; and

remodeling tissue of the heart by:

using a first elongate tool to intracorporeally actuate the first adjusting mechanism, and

using a second elongate tool to intracorporeally actuate the second adjusting mechanism.

21. Apparatus for use at a heart of a patient, the apparatus comprising:

an implant structure, comprising:

a body portion, configured to be secured inside the heart;

a first adjusting mechanism, coupled to a first portion of the body portion, and comprising a first ring that surrounds the first portion and is moveable with respect to the body portion; and

a second adjusting mechanism, coupled to a second portion of the body portion, and comprising a second ring that surrounds the second portion, and is moveable with respect to the body portion; and

a delivery system configured to implant the body portion inside the heart, the delivery system comprising:

a first elongate tool, configured to remodel tissue of the heart by actuating the first adjusting mechanism; and

a second elongate tool, configured to remodel tissue of the heart by actuating the second adjusting mechanism.

Assignments (2)
CHANGE OF NAME Recorded Sep 30, 2022
From: VALTECH CARDIO LTD.
To: EDWARDS LIFESCIENCES INNOVATION (ISRAEL) LTD.
Reel/Frame 061587/0710 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 11, 2022
From: MILLER, ERAN; REICH, TAL; GROSS, AMIR; SHEPS, TAL; CABIRI, OZ
To: VALTECH CARDIO LTD.
Reel/Frame 059894/0368 →
Continuity (7)
Continuation 16518781 · Jul 22, 2019
Continuation 15717440 · Sep 27, 2017
Continuation 14990172 · Jan 7, 2016
Continuation 14486226 · Sep 15, 2014
Continuation 13666262 · Nov 1, 2012
Provisional Application 61555570 · Nov 4, 2011
Related Publication 20220096233A1 · Mar 31, 2022
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