IP Library Granted Patent US 12,620,462
Granted Patent B2
US 12,620,462 · App. 17/573,725 · Granted May 5, 2026

Information system providing explanation of models

Inventors: Constantinos Ioannis Boussios (Chelsea, MA); Richard Gliklich (Weston, MA); Francis Thomas O'Donovan (Arlington, MA)
Assignee: OM1, Inc.
G16H10/60G06N5/022G06N20/00G16H50/70
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Quick Facts
Patent No.
US 12,620,462
App. No.
17/573,725
Granted
May 5, 2026
Kind
B2
Abstract

A health care information system generates information that describes how different inputs to a model affect the output of the model, by creating a localized model for a given entity, and determining how the output of the localized model for the given entity changes in response to different inputs. The computer system builds the localized model for a given entity based on the model and on data values for the given entity. The computer system inputs one or more different data values for selected input features of the localized model, while data values for the remaining input features of the localized model are fixed to data values for the given entity, and obtains corresponding outputs from the localized model. The results from this localized model for the given entity indicate which of the selected input features have the most impact on the output of the model for that entity.

Claims (55)

1 . A computer system, comprising:

a. a processing system comprising a processing device and computer storage, wherein the computer storage stores:

i. a first data structure including, for a plurality of entities, data values for input features for a trained computational model, wherein the data values for each entity are derived from a respective record for the entity in a data set, and

ii. a second data structure including data identifying a selected subset of the input features for the trained computational model, the selected subset having fewer features than the input features;

b. computer program code implementing the trained computational model which, when processed by the processing system, configures the processing system to apply input data values for the input features of a given entity to the trained computational model to output a predicted outcome for the given entity in response to the input data values for the input features of the entity;

c. computer program code that, when processed by the processing system, configures the processing system to generate a localized model for the given entity, wherein the localized model is distinct from and simplified with respect to the trained computational model and approximates the trained computational model, wherein the processing system generates the localized model based on a. the trained computational model and b. data values for the given entity from the first data structure for input features other than the selected subset of the input features identified by the second data structure, wherein the localized model has inputs and an output, wherein the inputs of the localized model correspond to only the selected subset of input features identified by the second data structure and the output of the localized model provides a predicted outcome for the given entity;

d. a sensitivity analysis module comprising computer program code that, when processed by the processing system, configures the processing system to analyze the localized model for the given entity by:

applying a plurality of different data values for the input features identified in the selected subset of the input features to the inputs of the localized model for the given entity, wherein the plurality of different data values are different from the data values for the selected subset of input features for the given entity as stored in the first data structure, whereby the localized model outputs respective predicted outcomes for the given entity for the different data values, and

storing, in the computer storage, the respective predicted outcomes output from the localized model for the given entity; and

e. a graphical user interface comprising computer program code that, when processed by the processing system, is responsive to the sensitivity analysis module to provide an output including human-understandable content describing how data values for the selected subset of input features likely would affect the predicted outcome of the trained computational model as applied to the given entity based on the stored respective predicted outcomes output from the localized model.

2 . The computer system of claim 1 , wherein the data set comprises health care information for a plurality of patients, wherein each patient in the plurality of patients has a respective record in the data set, and wherein the given entity is a given patient in the plurality of patients.

3 . The computer system of claim 1 , wherein the data set comprises health care information for a plurality of health care providers, wherein each health care provider in the plurality of health care providers has a respective record in the data set, and wherein the given entity is a given health care provider in the plurality of health care providers.

4 . The computer system of claim 1 , wherein the trained computational model is trained using a training set derived from the data set.

5 . The computer system of claim 1 , wherein the trained computational model performs classification of the entities into categories.

6 . The computer system of claim 1 , wherein the trained computational model computes risk factors associated with the entities.

7 . The computer system of claim 1 , wherein the entities are patients and the trained computational model computes predictions of outcomes for patients based on the records for the patients in the data set.

8 . The computer system of claim 1 , wherein the entities are patients and the trained computational model computes outcome scores for the patients based on the records for the patients in the data set.

9 . The computer system of claim 8 , wherein outcome scores are represented using an integer in a range of integer values.

10 . The computer system of claim 1 , wherein the entities are patients and the trained computational model computes factor scores for the patients based on the records for the patients in the data set.

11 . The computer system of claim 1 , wherein the second data structure comprises a library stored in the computer data storage including data representing the selected subset of input features.

12 . The computer system of claim 11 , wherein the selected subset of input features represented by the second data structure further correspond to actions which can be performed for the given entity.

13 . The computer system of claim 12 , wherein the library further includes a set of actionable factors, wherein the library stores, for each of the actionable factors, a mapping between the actionable factor and one or more respective input features in the selected subset of input features.

14 . The computer system of claim 13 , wherein the library further includes, for each actionable factor in the set of actionable factors, human-understandable content describing actions which can be performed for the given entity for output by the graphical user interface.

15 . The computer system of claim 13 , wherein the actionable factors include medically modifiable factors.

16 . The computer system of claim 12 , wherein the given entity comprises a patient and the actions include specifying a treatment for the patient.

17 . The computer system of claim 12 , wherein the given entity comprises a patient and the actions include specifying a behavior change for the patient.

18 . The computer system of claim 1 , wherein the sensitivity analysis module performs a sensitivity analysis on the localized model for the given entity wherein the first set of input features are held constant and sensitivity of the output of the localized model to variations in data values for the second set of input features is determined.

19 . The computer system of claim 18 wherein the sensitivity analysis uses a linear regression model.

20 . The computer system of claim 18 wherein the sensitivity analysis uses a nonlinear regression model.

21 . The computer system of claim 18 wherein the sensitivity analysis uses a Bayesian model.

22 . The computer system of claim 13 , wherein the second data structure maps an input feature in the selected subset of input features to a respective data value for the input feature for use as the different data value for the input feature by the sensitivity analysis module.

23 . The computer system of claim 1 , wherein the second data structure maps an input feature in the selected subset of input features to a respective data value for the input feature for use as the different data value for the input feature by the sensitivity analysis module.

24 . The computer system of claim 1 , wherein the graphical user interface further configures the computer system to receive a data value for an input feature in the selected subset of input features for use as the different data value for that input feature by the sensitivity analysis module.

25 . The computer system of claim 24 , wherein, to receive the data value for the input feature, the graphical user interface configures the computer system to:

access current data values for the given patient for medically modifiable factors;

present the current data values in a display, and

receive inputs indicating changes to the current data values.

26 . The computer system of claim 25 , wherein the medically modifiable factors include one or more of weight of a patient, body mass index of the patient, physical activity level of the patient, diabetes control of the patient, or smoking habits of the patient.

27 . The computer system of claim 1 wherein the localized model is a linear model.

28 . A computer system, comprising:

a. a processing system comprising a processing device and computer storage, wherein the computer storage stores:

i. a first data structure including, for each entity in a plurality of entities, respective data values for the entity for input features of a trained computational model, wherein the trained computational model outputs a predicted outcome for an entity based on the respective data values for the entity for the input features, and

ii. a second data structure comprising data describing a set of actionable factors related to a selected subset of the input features, the selected subset having fewer features than the input features, the second data structure including, for each actionable factor:

a) respective human-understandable content describing an action which can be performed for the given entity to affect the actionable factor, and

b) a respective mapping between the actionable factor and one or more respective input features in the selected subset of input features; and

b. computer program code that, when processed by the processing system, configures the processing system to:

construct a localized model of the trained computational model for a given entity, wherein the localized model is equivalent to the trained computational model by having fixed values for input features based on the respective data values for the given entity from the first data structure for input features other than the selected subset of the input features identified by the second data structure, wherein the localized model has variable inputs corresponding to only the selected subset of input features identified by the second data structure and has an output providing a predicted outcome for the given entity,

generate a respective predicted outcome for the given entity for different data values by applying the different data values for the input features identified in the selected subset of the input features to the variable inputs of the localized model for the given entity, wherein the different data values are different from the data values for the selected subset of input features for the given entity as stored in the first data structure; and

c. a graphical user interface comprising computer program code that, when processed by the processing system, configures the processing system to:

access current data values for the given entity for input features related to the actionable factors,

apply the current data values to the input features of the trained computational model to cause the trained computational model to output a respective predicted outcome,

present the current data values and the respective predictive outcome from the trained computational model in a display,

receive an input indicating a change to at least one of the current data values to generate changed data values for at least one of the input features related to the actionable factors,

cause the processing system to generate a predicted outcome output from the localized model for the given entity based on the changed data values by applying the changed data values as the different data values to the input features of the localized model for the given entity, and

using the second data structure, output human-understandable content describing how the changed data values likely would affect the predicted outcome of the trained computational model as applied to the given entity based on the predicted outcome output from the localized model.

Assignments (1)
SECURITY INTEREST Recorded Aug 12, 2025
From: OM1, INC.
To: COMERICA BANK
Reel/Frame 071997/0292 →
Continuity (3)
Continuation 15927766 · Mar 21, 2018
Provisional Application 62474587 · Mar 21, 2017
Related Publication 20220148695A1 · May 12, 2022
References Cited (197)
US 5486999A · Mebane · 1996 [cited by applicant]
US 5508912A · Schneiderman · 1996 [cited by applicant]
US 5619421A · Venkataraman et al. · 1997 [cited by applicant]
US 5961332A · Joao · 1999 [cited by applicant]
US 6101511A · Derose et al. · 2000 [cited by applicant]
US 6317731B1 · Luciano · 2001 [cited by applicant]
US 6524241B2 · Iliff · 2003 [cited by applicant]
US 6687685B1 · Sadeghi et al. · 2004 [cited by applicant]
US 7076437B1 · Levy · 2006 [cited by applicant]
US 7194301B2 · Jenkins et al. · 2007 [cited by applicant]
US 7433519B2 · Rynderman · 2008 [cited by applicant]
US 7739126B1 · Cave et al. · 2010 [cited by applicant]
US 7809660B2 · Friedlander et al. · 2010 [cited by applicant]
US 7916363B2 · Rynderman · 2011 [cited by applicant]
US 7930262B2 · Friedlander et al. · 2011 [cited by applicant]
US 7949620B2 · Otte et al. · 2011 [cited by applicant]
US 8090590B2 · Fotsch et al. · 2012 [cited by applicant]
US 8140541B2 · Koss · 2012 [cited by applicant]
US 8154776B2 · Rynderman · 2012 [cited by applicant]
US 8165973B2 · Alexe et al. · 2012 [cited by applicant]
US 8190451B2 · Lloyd et al. · 2012 [cited by applicant]
US 8311849B2 · Soto et al. · 2012 [cited by applicant]
US 8335698B2 · Angell et al. · 2012 [cited by applicant]
US 8392215B2 · Tawil · 2013 [cited by applicant]
US 8538773B2 · Morris et al. · 2013 [cited by applicant]
US 8560281B2 · Spertus et al. · 2013 [cited by applicant]
US 8583586B2 · Ebadollahi et al. · 2013 [cited by applicant]
US 8930223B2 · Friedlander et al. · 2015 [cited by applicant]
US 9514416B2 · Lee et al. · 2016 [cited by applicant]
US 9646271B2 · Friedlander et al. · 2017 [cited by applicant]
US 9690844B2 · Mukherjee et al. · 2017 [cited by applicant]
US 10061812B2 · Marshall et al. · 2018 [cited by applicant]
US 10282512B2 · Bennett et al. · 2019 [cited by applicant]
US 10311363B1 · Florissi et al. · 2019 [cited by applicant]
US 10311975B2 · Young et al. · 2019 [cited by applicant]
US 10706329B2 · Anushiravani et al. · 2020 [cited by applicant]
US 10731223B2 · Kennedy et al. · 2020 [cited by applicant]
US 10731233B2 · Yamada et al. · 2020 [cited by applicant]
US 11257574B1 · Boussios et al. · 2022 [cited by applicant]
US 11527326B2 · McNair et al. · 2022 [cited by applicant]
US 11594310B1 · Bradley et al. · 2023 [cited by applicant]
US 11594311B1 · Bradley et al. · 2023 [cited by applicant]
US 11862346B1 · Boussios et al. · 2024 [cited by applicant]
US 11967428B1 · Boussios et al. · 2024 [cited by applicant]
US 12057204B2 · Bradley et al. · 2024 [cited by applicant]
US 12142355B2 · Bradley et al. · 2024 [cited by applicant]
US 20030014284A1 · Jones · 2003 [cited by applicant]
US 20040122706A1 · Walker et al. · 2004 [cited by applicant]
US 20040122707A1 · Sabol et al. · 2004 [cited by applicant]
US 20040243362A1 · Liebman · 2004 [cited by applicant]
US 20060058384A1 · Hogg · 2006 [cited by applicant]
US 20060129427A1 · Wennberg · 2006 [cited by examiner]
US 20060129428A1 · Wennberg · 2006 [cited by applicant]
US 20060173663A1 · Langheier et al. · 2006 [cited by applicant]
US 20070021979A1 · Cosentino et al. · 2007 [cited by applicant]
US 20070172907A1 · Volker et al. · 2007 [cited by applicant]
US 20070255113A1 · Grimes · 2007 [cited by applicant]
US 20080171916A1 · Feder et al. · 2008 [cited by applicant]
US 20080208813A1 · Friedlander et al. · 2008 [cited by applicant]
US 20080235049A1 · Morita · 2008 [cited by examiner]
US 20080294459A1 · Angell et al. · 2008 [cited by applicant]
US 20090119337A1 · Biedermann · 2009 [cited by applicant]
US 20090164237A1 · Hunt et al. · 2009 [cited by applicant]
US 20090259494A1 · Feder et al. · 2009 [cited by applicant]
US 20090287503A1 · Angell et al. · 2009 [cited by applicant]
US 20100021956A1 · Shearer · 2010 [cited by examiner]
US 20100191088A1 · Anderson et al. · 2010 [cited by applicant]
US 20100240035A1 · Jablons et al. · 2010 [cited by applicant]
US 20100324927A1 · Tinsley · 2010 [cited by applicant]
US 20110010328A1 · Patel et al. · 2011 [cited by applicant]
US 20110071363A1 · Montijo et al. · 2011 [cited by applicant]
US 20110106558A1 · Solito et al. · 2011 [cited by applicant]
US 20110125680A1 · Bosworth · 2011 [cited by examiner]
US 20110177956A1 · Korenberg · 2011 [cited by applicant]
US 20110288877A1 · Ofek et al. · 2011 [cited by applicant]
US 20120065987A1 · Farooq et al. · 2012 [cited by applicant]
US 20120084064A1 · Dzenis et al. · 2012 [cited by applicant]
US 20120110016A1 · Phillips · 2012 [cited by applicant]
US 20120179478A1 · Ross · 2012 [cited by applicant]
US 20120191640A1 · Ebadollahi et al. · 2012 [cited by applicant]
US 20120215560A1 · Ofek et al. · 2012 [cited by applicant]
US 20120254098A1 · Flinn et al. · 2012 [cited by applicant]
US 20120296675A1 · Silverman · 2012 [cited by applicant]
US 20130185231A1 · Baras et al. · 2013 [cited by applicant]
US 20140006447A1 · Friedlander et al. · 2014 [cited by applicant]
US 20140074510A1 · McClung · 2014 [cited by examiner]
US 20140081898A1 · Saigal et al. · 2014 [cited by applicant]
US 20140095204A1 · Fung et al. · 2014 [cited by applicant]
US 20140108044A1 · Reddy et al. · 2014 [cited by applicant]
US 20140164022A1 · Reed et al. · 2014 [cited by applicant]
US 20140249834A1 · D'souza et al. · 2014 [cited by applicant]
US 20140350954A1 · Ellis et al. · 2014 [cited by applicant]
US 20150106109A1 · Crowley et al. · 2015 [cited by applicant]
US 20150106115A1 · Hu et al. · 2015 [cited by applicant]
US 20150235001A1 · Fouts · 2015 [cited by applicant]
US 20150339442A1 · Oleynik · 2015 [cited by applicant]
US 20150347599A1 · Mcmains et al. · 2015 [cited by applicant]
US 20160004840A1 · Rust et al. · 2016 [cited by applicant]
US 20160012202A1 · Hu et al. · 2016 [cited by applicant]
US 20160015347A1 · Bregman-Amitai et al. · 2016 [cited by applicant]
US 20160029919A1 · Hebert et al. · 2016 [cited by applicant]
US 20160078183A1 · Trygstad et al. · 2016 [cited by applicant]
US 20160120481A1 · Li et al. · 2016 [cited by applicant]
US 20160188814A1 · Raghavan et al. · 2016 [cited by applicant]
US 20160188834A1 · Erdmann et al. · 2016 [cited by applicant]
US 20160196394A1 · Chanthasiriphan et al. · 2016 [cited by applicant]
US 20160235373A1 · Sharma et al. · 2016 [cited by applicant]
US 20160283679A1 · Hu et al. · 2016 [cited by applicant]
US 20160283686A1 · Hu et al. · 2016 [cited by applicant]
US 20160354039A1 · Soto et al. · 2016 [cited by applicant]
US 20170046602A1 · Hu et al. · 2017 [cited by applicant]
US 20170061093A1 · Amarasingham · 2017 [cited by examiner]
US 20170124263A1 · Crafts et al. · 2017 [cited by applicant]
US 20170124279A1 · Rothman · 2017 [cited by applicant]
US 20170147777A1 · Kin et al. · 2017 [cited by applicant]
US 20170235887A1 · Cox et al. · 2017 [cited by applicant]
US 20170262609A1 · Perlroth et al. · 2017 [cited by applicant]
US 20170323075A1 · Krause · 2017 [cited by examiner]
US 20180268937A1 · Spetzler et al. · 2018 [cited by applicant]
US 20180330805A1 · Cheung et al. · 2018 [cited by applicant]
US 20180336319A1 · Itu et al. · 2018 [cited by applicant]
US 20190079938A1 · Agrawal et al. · 2019 [cited by applicant]
US 20190244714A1 · Morra et al. · 2019 [cited by applicant]
US 20210098090A1 · Thomas et al. · 2021 [cited by applicant]
US 20230197223A1 · Bradley et al. · 2023 [cited by applicant]
US 20230197224A1 · Bradley et al. · 2023 [cited by applicant]
US 20240096500A1 · Boussios et al. · 2024 [cited by applicant]
US 20240153647A1 · Boussios et al. · 2024 [cited by applicant]
US 20240290491A1 · Boussios et al. · 2024 [cited by applicant]
EP 2614480A2 · 2013 [cited by applicant]
WO 0057310A1 · 2000 [cited by applicant]
WO 0209004A1 · 2002 [cited by applicant]
WO 0209580A1 · 2002 [cited by applicant]
WO 2003104939A2 · 2003 [cited by applicant]
WO 2006086181A1 · 2006 [cited by applicant]
WO 2007050147A1 · 2007 [cited by applicant]
WO 2008048662A2 · 2008 [cited by applicant]
WO 2008079341A2 · 2008 [cited by applicant]
WO 2012019000A2 · 2012 [cited by applicant]
WO 2014028541A1 · 2014 [cited by applicant]
WO 2015169810A1 · 2015 [cited by applicant]
Awan et al., “Machine Learning-Based Prediction of Heart Failure Readmission or Death: Implications of Choosing the Right Model and the Right Metrics”, ESC Heart Failure, DOI: 10.1002/ehf2.12419, vol. 6, Feb. 27, 2019, … [cited by applicant]
Dua et al., “Machine Learning in Healthcare Informatics”, Intelligent Systems Reference Library, Springer, vol. 56, 2014, 334 Pages. [cited by applicant]
U.S. Patent and Trademark Office, “Final Office Action Received”, U.S. Appl. No. 16/386,123, Mar. 31, 2023, 59 Pages. [cited by applicant]
U.S. Patent and Trademark Office, “Non-Final Office Action Received”, U.S. Appl. No. 18/169,363, Jul. 7, 2023, 48 Pages. [cited by applicant]
U.S. Patent and Trademark Office, “Notice of Allowance Received”, U.S. Appl. No. 16/724,264, Sep. 6, 2023, 7 Pages. [cited by applicant]
U.S. Patent and Trademark Office, “Notice of Allowance Received”, U.S. Appl. No. 15/465,550, Jan. 26, 2023, 8 Pages. [cited by applicant]
U.S. Patent and Trademark Office, “Notice of Allowance Received”, U.S. Appl. No. 16/724,264, May 22, 2023, 8 Pages. [cited by applicant]
Bertens, et al., “A nomogram was developed to enhance the use of multinomial logistic regression modeling in diagnostic research”, Mar. 2016, Journal of Clinical Epidemiology, pp. 51-57. (Year: 2016). [cited by applicant]
Cheng, et al., “Risk Prediction with Electronic Health Records: A Deep Learning Approach”, Proceedings of the SIAM International Conference on Data Mining, Jun. 2016, 9 Pages. [cited by applicant]
Clockbackward, “Ordinary Least Squares Linear Regression: Flaws, Problems and Pitfalls”, Jun. 18, 2009, 16 Pages. [cited by applicant]
Grossman, et al., “Learning Bayesian Network Classifiers by Maximizing Conditional Likelihood”, Department of Computer Science and Engineering, University of Washington, Seattle, WA, 2004 (Year: 2004), 8 Pages. [cited by applicant]
Hileman, “Accuracy of Claims-Based Risk Scoring Models”, Society of Actuaries, Oct. 2016, pp. 1-90. [cited by applicant]
McCarthy, et al., “The Estimation of Sensitivity and Specificity of Clustered Binary Data”, Statistics and Data Analysis, SUGI 31, Paper 206-31, 10 pages. [cited by applicant]
Mojsilovic, et al., “Semantic based categorization, browsing and retrieval in medical image databases”, Proceedings of the International Conference on Image Processing, IEEE, 2002, pp. 145-148., 2002. [cited by applicant]
Pearson, et al., “Disease Progression Modeling from Historical Clinical Databases”, Proceedings of the Eleventh ACM SIGKDD International Conference on Knowledge Discovery in Data Mining, Aug. 21-24, 2005, pp. 788-793. [cited by applicant]
Ribeiro, “Why Should I Trust You?”, Explaining the Predictions of Any Classifier, Feb. 16, 2016, 10 Pages. [cited by applicant]
Schneider, “Enabling Advanced Analytics to Improve Outcomes”, Truven Health Analytics, Aug. 23, 2012, pp. 1-46, Aug. 23, 2012, 46. [cited by applicant]
Shen, “Using Cluster Analysis, Cluster Validation, and Consensus Clustering to Identify Subtypes of Pervasive Developmental Disorders”, Nov. 2007, 119 pages , Nov. 2007, 119 pages. [cited by applicant]
Soni, et al., “Using Associative Classifiers for Predictive Analysis in Health Care Data Mining”, International Journal of Computer Applications (0975-8887), vol. 4, No. 5, Jul. 2010, pp. 33-37. [cited by applicant]
Su, et al., “Using Bayesian Networks to Discover Relations Between Genes, Environment, and Disease”, BioData http://www.biodatamining.org/content/6/1/6, 2013 (Year: 2013), 21 Pages. [cited by applicant]
Suo, et al., “Risk Factor Analysis Based on Deep Learning Models”, Proceedings of the 7th ACM International Conference on Bioinformatics, Computational Biology, and Health Informatics, Oct. 2-5, 2016, 10 Pages. [cited by applicant]
Tan, et al., “Cluster Analysis: Basic Concepts and Algorithms,”, Introduction to Data Mining (Second Edition), Chapter 8, Feb. 2018, pp. 487-568, Feb. 2018, 82. [cited by applicant]
Truven Health Analytics, “Flexible Analytics for Provider Evaluation”, Solution Spotlight, 2017, 4 Pages. [cited by applicant]
Truven Health Analytics, “Modeling Studies: Published Articles and Presentations”, 2016, pp. 1-6. [cited by applicant]
Truven Health Groups, “Enterprise Decision Support”, Product Spotlight, 2012, 2 Pages. [cited by applicant]
U.S. Patent and Trademark Office, “Final Office Action Received”, U.S. Appl. No. 15/465,542, Jan. 4, 2022 60 pages. [cited by applicant]
U.S. Patent and Trademark Office, “Final Office Action Received”, U.S. Appl. No. 15/465,542, Dec. 30, 2019, 54 Pages. [cited by applicant]
U.S. Patent and Trademark Office, “Final Office Action Received”, U.S. Appl. No. 15/465,550, Mar. 21, 2022, 12 Pages. [cited by applicant]
U.S. Patent and Trademark Office, “Final Office Action Received”, U.S. Appl. No. 15/927,766, Oct. 6, 2020, 22 Pages. [cited by applicant]
U.S. Patent and Trademark Office, “Final Office Action Received”, U.S. Appl. No. 15/465,550, Oct. 14, 2020, 15 Pages. [cited by applicant]
U.S. Patent and Trademark Office, “Non Final Office Action Received”, U.S. Appl. No. 16/386,123, Jun. 28, 2022, 55 Pages. [cited by applicant]
U.S. Patent and Trademark Office, “Non Final Office Action Received”, U.S. Appl. No. 15/927,766, Apr. 30, 2020, 19 Pages. [cited by applicant]
U.S. Patent and Trademark Office, “Non Final Office Action Received”, U.S. Appl. No. 15/465,550, Jun. 26, 2019, 8 Pages. [cited by applicant]
U.S. Patent and Trademark Office, “Non Final Office Action Received”, U.S. Appl. No. 15/465,550, Mar. 13, 2020, 12 Pages. [cited by applicant]
U.S. Patent and Trademark Office, “Non Final Office Action Received”, U.S. Appl. No. 15/465,542, Mar. 19, 2019, 29 Pages. [cited by applicant]
U.S. Patent and Trademark Office, “Non-Final Office Action Received”, U.S. Appl. No. 15/465,542, Apr. 1, 2021, 73 Pages. [cited by applicant]
U.S. Patent and Trademark Office, “Non-Final Office Action Received”, U.S. Appl. No. 15/465,550, Jul. 29, 2021, 31 Pages. [cited by applicant]
U.S. Patent and Trademark Office, “Non-Final Office Action Received”, U.S. Appl. No. 16/724,264, Mar. 21, 2022, 20 Pages. [cited by applicant]
U.S. Patent and Trademark Office, “Notice of Allowance Received”, U.S. Appl. No. 15/927,766, Oct. 14, 2021, 35 Pages. [cited by applicant]
U.S. Patent and Trademark Office, “Restriction Requirement Received”, U.S. Appl. No. 16/724,264, Oct. 7, 2021, 6 Pages. [cited by applicant]
U.S. Patent and Trademark Office, “Notice of Allowance Received”, U.S. Appl. No. 15/465,550, Aug. 16, 2022, 8 Pages. [cited by applicant]
U.S. Patent and Trademark Office, “Notice of Allowance Received”, U.S. Appl. No. 15/465,542, Aug. 24, 2022, 11 Pages. [cited by applicant]
Bodhe, et al., “A Proposed Mobile Based Health Care System for Patient Diagnosis using Android OS,” International Journal of Computer Science and Mobile Computing, vol. 3 Issue.5, May 2014, p. 422-427 (Year: 2014). [cited by applicant]
U.S. Patent and Trademark Office, “Notice of Allowance Received”, U.S. Appl. No. 15/465,542, Oct. 28, 2022, 12 Pages. [cited by applicant]
U.S. Patent and Trademark Office, “Final Office Action Received”, U.S. Appl. No. 16/724,264, Nov. 30, 2022, 11 Pages. [cited by applicant]
U.S. Patent and Trademark Office , “Final Office Action Received”, U.S. Appl. No. 18/414,296, Jul. 10, 2024, 11 Pages. [cited by applicant]
U.S. Patent and Trademark Office , “Non-Final Office Action Received”, U.S. Appl. No. 18/414,296, Mar. 22, 2024, 13 Pages. [cited by applicant]
U.S. Patent and Trademark Office , “Non-Final Office Action Received”, U.S. Appl. No. 18/169,372, May 8, 2024, 16 Pages. [cited by applicant]
U.S. Patent and Trademark Office , “Non-Final Office Action Received”, U.S. Appl. No. 18/596,720, Sep. 16, 2024, 37 Pages. [cited by applicant]
U.S. Patent and Trademark Office , “Notice of Allowability Received”, U.S. Appl. No. 18/169,372, Oct. 16, 2024, 2 Pages. [cited by applicant]
U.S. Patent and Trademark Office , “Notice of Allowance Received”, U.S. Appl. No. 16/386,123, Dec. 13, 2023, 12 Pages. [cited by applicant]
U.S. Patent and Trademark Office , “Notice of Allowance Received”, U.S. Appl. No. 18/169,363, Mar. 27, 2024, 10 Pages. [cited by applicant]
U.S. Patent and Trademark Office , “Notice of Allowance Received”, U.S. Appl. No. 18/169,372, Sep. 25, 2024, 9 Pages. [cited by applicant]
Voshaar , et al., “Calibration of the PROMIS Physical Function Item Bank in Dutch Patients with Rheumatoid Arthritis”, PLOS ONE, vol. 9, Issue 3, Mar. 2014, pp. 1-11. [cited by applicant]
Zhong, Yizhen , et al., “Characterizing Design Patterns of EHR-Driven Phenotype Extraction Algorithms”, In 2018 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), Madrid, Spain, 2018; doi: 10.1109/B… [cited by applicant]
U.S. Appl. No. 19/192,428, Non-Final Office Action mailed on Feb. 3, 2026, 37 pages. [cited by applicant]