IP Library › Patent Application 17578669
Patent Application
App. No. 17/578,669

TOPICAL COMPOSITIONS AND METHODS OF USE THEREOF

Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US None
App. No.
17/578,669
Abstract

The invention is directed to a topical composition comprising one or more topical active ingredients, one or more nonionic surfactants, one or more viscosity enhancers, polyethylene glycol and menthol. The invention is further directed to a method of reducing or eliminating pain comprising applying a composition of the present invention to a subject in need thereof.

Claims (25)

1 . A topical skin composition comprising one or more nonionic surfactants, a viscosity enhancer, polyethylene glycol, menthol and one or more active ingredients.

2 . The composition of claim 1 , wherein the one or more nonionic surfactants is selected from the group consisting of poloxamers, polysorbates, cyclodextrins, alkylaryl polyethers, polyoxyethyleneglycol alkyl ethers, tyloxapol, and polyoxyls.

3 . The composition of claim 1 , wherein the one or more nonionic surfactants are poloxamers and polyoxyls.

4 . The composition of claim 1 , wherein the one or more nonionic surfactants are poloxamer 407, poloxamer 188 and polyoxyl castor oil.

5 . The composition of claim 1 , wherein the one or more nonionic surfactants are at a total concentration of from about 1.0% to about 7.0% w/v, wherein w/v denotes weight by total volume of the composition.

6 . The composition of claim 5 , wherein the one or more nonionic surfactants are at a total concentration of from about 1.0% to about 2.0% w/v.

7 . The composition of claim 1 , wherein the one or more viscosity enhancers are selected from the group consisting of cellulose derivatives, carbomers, gums, dextrans, polyvinyl alcohol, polyacrylic acids, povidone, polyethylene glycol, propylene glycol, chitosans, and hyaluronates and hyaluronic acids.

8 . The composition of claim 1 , wherein the one or more viscosity enhancers is carbomer.

9 . The composition of claim 1 , wherein the one or more viscosity enhancers are at a total concentration of from about 0.05% to about 2.0% w/v, wherein w/v denotes weight by total volume of the composition.

10 . The composition of claim 1 , wherein the one or more viscosity enhancers are at a total concentration of from about 0.5% to about 1.5% w/v.

11 . The composition of claim 1 , wherein the polyethylene glycol is polyethylene glycol 400.

12 . The composition of claim 1 , wherein the polyethylene glycol is from about 0.1% to about 5% w/v, wherein w/v denotes weight by total volume of the composition.

13 . The composition of claim 12 , wherein the polyethylene glycol is from about 0.1% to about 1% w/v.

14 . The composition of claim 1 , wherein the menthol is at a concentration from about 0.1% to about 2% w/v, wherein w/v denotes weight by total volume of the composition.

15 . The composition of claim 1 , wherein the menthol is at a concentration from about 0.5% to about 1% w/v.

16 . A method of reducing or eliminating pain comprising applying a composition of claim 1 to a subject in need thereof.

17 . A topical skin composition comprising:

one or more active ingredients selected from the group consisting of acetaminophen, acetylsalicylic acid, celecoxib, diclofenac, diflunisal, etodolac, fenoprofen, flurbiprofen, ibuprofen, indomethacin, ketoprofen, ketorolac, lidocaine, mefenamic acid, meloxicam, nabumetone, naproxen, oxaprozin, piroxicam, salsalate, sulindac, tolmetin, capsaicin, menthol, camphor and any combinations thereof;

poloxamer 407;

poloxamer 188;

polyoxyl castor oil;

polyethylene glycol 400;

menthol; and

a carbomer.

18 . A method of reducing or eliminating pain comprising applying a composition of claim 17 to a subject in need thereof.