IP Library › Granted Patent US 12,502,277
Granted Patent B2
US 12,502,277 · App. 17/581,821 · Granted Dec 23, 2025

Contraction of an annuloplasty structure

Inventor: Assaf Sharon (Tel Aviv, IL)
Assignee: Edwards Lifesciences Innovation (Israel) Ltd.
A61F2/2445A61F2/2466A61B2017/0649A61F2220/0016
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Quick Facts
Patent No.
US 12,502,277
App. No.
17/581,821
Granted
Dec 23, 2025
Kind
B2
Abstract

Using a delivery tool, an annuloplasty structure is secured on an annulus of a valve of a subject, the annuloplasty structure including (i) a flexible sleeve that defines a longitudinal lumen therethrough, and (ii) an elongate contraction member attached to the flexible sleeve. Subsequently, while the delivery tool is coupled to the annuloplasty structure, the sleeve is longitudinally contracted by drawing the contraction member into the lumen. Other embodiments are also described.

Claims (46)

1 . A method, comprising:

using a delivery tool, securing an annuloplasty structure on an annulus of a valve of a subject, the annuloplasty structure including (i) a flexible sleeve that defines a longitudinal lumen therethrough, and (ii) an elongate contraction member attached to the flexible sleeve; and

subsequently, while the delivery tool is coupled to the annuloplasty structure, longitudinally contracting the sleeve by drawing the contraction member into the lumen;

wherein:

a portion of the delivery tool slides within the lumen of the sleeve;

the method further comprises maintaining coupling of the delivery tool to the annuloplasty structure by maintaining the portion of the delivery tool within the lumen;

maintaining the coupling of the delivery tool comprises pushing outwardly coupling elements of the delivery tool that are coupled to the sleeve of the annuloplasty structure; and

the method further comprises decoupling the delivery tool from the annuloplasty structure by removing the portion of the delivery tool from within the lumen and allowing the coupling elements to flex inwardly and disengage from the sleeve of the annuloplasty structure.

2 . The method according to claim 1 , wherein the delivery tool is coupled to the annuloplasty structure at a proximal end thereof, and wherein the step of longitudinally contracting the sleeve by drawing the contraction member into the lumen comprises longitudinally contracting the sleeve by longitudinally pulling the contraction member proximally into the lumen.

3 . The method according to claim 1 , wherein the sleeve includes a circumferential wall that defines the lumen, and wherein the step of securing the annuloplasty structure on the annulus comprises sequentially, for each anchor of a plurality of anchors:

advancing an anchor of the plurality of anchors into the lumen of the sleeve, and driving a tissue-engaging element of the anchor of the plurality of anchors through the circumferential wall and into the annulus, such that an anchor head of the anchor of the plurality of anchors remains in the lumen of the sleeve.

4 . The method according to claim 1 , further comprising, subsequently to the step of longitudinally contracting the sleeve, maintaining a contraction state of the sleeve by locking a locking mechanism to the contraction member.

5 . The method according to claim 4 , wherein the step of locking the locking mechanism comprises locking the locking mechanism while maintaining coupling of the delivery tool to the annuloplasty structure.

6 . The method according to claim 4 , further comprising, prior to the step of locking the locking mechanism, delivering a force-distributing element within the lumen of the sleeve and facilitating distributing of contraction forces along the annuloplasty structure using the force-distributing element.

7 . The method according to claim 6 , wherein the step of securing the annuloplasty structure comprises implanting a plurality of tissue anchors, and wherein the step of delivering the force-distributing element comprises distributing the contraction forces along a subset of the plurality of tissue anchors.

8 . The method according to claim 6 , wherein the step of locking the locking mechanism comprises locking in place the force-distributing element.

9 . The method according to claim 1 , wherein the contraction member is provided with a loop and wherein the loop surrounds a portion of the delivery tool during the securing of the annuloplasty structure on the annulus.

10 . The method according to claim 9 , wherein the step of longitudinally contracting comprises:

retracting the portion of the delivery tool until the loop does not surround the portion of the delivery tool,

gripping the loop; and

subsequently, longitudinally pulling the contraction member by pulling the loop.

11 . The method according to claim 9 , wherein the step of securing the annuloplasty structure on the annulus comprises:

advancing the portion of the delivery tool through the lumen of the sleeve while the loop surrounds the portion of the delivery tool,

delivering a plurality of tissue anchors through the portion of the delivery tool; and

using the delivery tool, while the loop surrounds the portion of the delivery tool, anchoring the annuloplasty structure to the annulus by driving each one of the plurality of tissue anchors through respective portions of the sleeve and into tissue of the annulus.

12 . The method according to claim 11 , wherein the step of advancing the portion of the delivery tool through the lumen of the sleeve comprises moving the portion of the delivery tool with respect to the loop, while the loop remains stationary.

13 . The method according to claim 11 , wherein the step of advancing the portion of the delivery tool through the lumen of the sleeve comprises advancing the portion of the delivery tool distally through the lumen, and wherein driving each one of the plurality of tissue anchors through the respective portions of the sleeve comprises retracting the portion of the delivery tool proximally with each successive driving.

14 . The method according to claim 1 , wherein the step of maintaining the coupling of the delivery tool further comprises maintaining a closure mechanism of the annuloplasty structure in an open state by maintaining the portion of the delivery tool within the lumen.

15 . The method according to claim 14 , wherein the step of decoupling the delivery tool from the annuloplasty structure further comprises transitioning the closure mechanism to a closed state.

16 . The method according to claim 1 , wherein:

the step of securing the annuloplasty structure on the annulus of the valve comprises securing the annuloplasty structure on the annulus of the valve while part of the contraction member is disposed within the lumen, and

the step of longitudinally contracting the sleeve by drawing the contraction member into the lumen comprises longitudinally contracting the sleeve by drawing the contraction member further into the lumen.

17 . A method, comprising:

using a delivery tool, securing an annuloplasty structure on an annulus of a valve of a subject, the annuloplasty structure including (i) a flexible sleeve that defines a longitudinal lumen therethrough, and (ii) an elongate contraction member attached to the flexible sleeve; and

subsequently, while the delivery tool is coupled to the annuloplasty structure, longitudinally contracting the sleeve by drawing the contraction member into the lumen;

wherein:

the contraction member is provided with a loop;

the loop surrounds a portion of the delivery tool during the securing of the annuloplasty structure on the annulus; and

the securing the annuloplasty structure on the annulus comprises:

advancing the portion of the delivery tool through the lumen of the sleeve while the loop surrounds the portion of the delivery tool;

delivering a plurality of tissue anchors through the portion of the delivery tool; and

using the delivery tool, while the loop surrounds the portion of the delivery tool, anchoring the annuloplasty structure to the annulus by driving each one of the plurality of tissue anchors through respective portions of the sleeve and into tissue of the annulus.

18 . A method, comprising:

using a delivery tool, securing an annuloplasty structure on an annulus of a valve of a subject, the annuloplasty structure including (i) a flexible sleeve that defines a longitudinal lumen therethrough, and (ii) an elongate contraction member attached to the flexible sleeve; and

subsequently, while the delivery tool is coupled to the annuloplasty structure, longitudinally contracting the sleeve by drawing the contraction member into the lumen and thereby increasing a longitudinal proportion of the contraction member that is disposed within the lumen.

19 . The method according to claim 18 , wherein the step of drawing the contraction member into the lumen further comprises drawing a portion of the contraction member into the delivery tool.

Assignments (2)
CHANGE OF NAME Recorded Sep 30, 2022
From: VALTECH CARDIO LTD.
To: EDWARDS LIFESCIENCES INNOVATION (ISRAEL) LTD.
Reel/Frame 061587/0710 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 11, 2022
From: SHARON, ASSAF
To: VALTECH CARDIO LTD.
Reel/Frame 059894/0781 →
Continuity (3)
Continuation PCTIL2020050808 · Jul 22, 2020
Provisional Application 62877776 · Jul 23, 2019
Related Publication 20220142779A1 · May 12, 2022
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