IP Library Granted Patent US 11,617,530
Granted Patent B2
US 11,617,530 · App. 17/584,076 · Granted Apr 4, 2023

Apparatus and methods for removing a large-signal voltage offset from a biomedical signal

Inventors: Budimir S. Drakulic (Los Angeles, CA); Sina Fakhar (Encino, CA); Thomas G. Foxall (Surrey, CA); Branislav Vlajinic (Los Angeles, CA)
Assignee: BioSig Technologies, Inc.
A61B5/30A61B5/0245A61B5/308A61B5/318A61B5/7203A61B5/7225A61B5/7246A61B5/0006A61B5/0215A61B5/02405A61B5/0538A61B5/352A61B5/361A61B5/363A61B5/366A61B5/4836A61B5/7217A61B5/742A61B5/7435A61B18/1492A61B2018/00351A61B2018/00577A61B2562/18A61B2562/223G16H40/63H01L2924/14335H02H9/04H02H9/045H03F3/45H03F3/45475H03F3/68H03F2200/129H03F2200/171H03F2200/234H03F2200/375H03F2200/451H03F2203/45116H03F2203/45528H03F2203/45601H03K5/125H04L43/02H04L47/50
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Quick Facts
Patent No.
US 11,617,530
App. No.
17/584,076
Granted
Apr 4, 2023
Kind
B2
Abstract

Apparatus and methods remove a voltage offset from an electrical signal, specifically a biomedical signal. A signal is received at a first operational amplifier and is amplified by a gain. An amplitude of the signal is monitored, by a first pair of diode stages coupled to an output of the first operational amplifier, for the voltage offset. The amplitude of the signal is then attenuated by the first pair of diode stages and a plurality of timing banks. The attenuating includes limiting charging, by the first pair of diode stages, of the plurality of timing banks and setting a time constant based on the charging. The attenuating removes the voltage offset persisting at a threshold for a duration of at least the time constant. Saturation of the signal is limited to a saturation recovery time while the saturated signal is gradually pulled into monitoring range over the saturation recovery time.

Claims (12)

1. A system for removing noise in electrocardiogram (ECG) and intracardiac (IC) signals, comprising:

a Wilson Central Terminal (WCT) circuit configured to be coupled to two limb electrodes, wherein the WCT circuit operates as a reference for unipolar IC leads;

a right-leg drive (RLD) circuit configured to be coupled to a third limb electrode; and

a twin-T network, coupled to the RLD circuit, comprising a first twin-T circuit coupled to a second twin-T circuit and an operational amplifier;

wherein a node of the first twin-T circuit is coupled to a first input of the operational amplifier, the two limb electrodes are coupled to a second input of the operational amplifier, and an output of the operational amplifier is coupled to an input of the RLD circuit, and wherein a node of the second twin-T circuit is coupled to the output of the operational amplifier.

2. The system of claim 1 , wherein the RLD circuit is configured to remove common mode voltage from a signal received at the input of the RLD circuit.

3. The system of claim 1 , wherein the RLD circuit is configured to prevent current having an amplitude greater than one microampere from flowing to the third limb electrode.

4. The system of claim 1 , wherein the twin-T network comprises a notch filter in a feedback path of the twin-T network.

5. The system of claim 1 , wherein the twin-T network is configured to provide enhanced common mode rejection of a first harmonic frequency and a third harmonic frequency of power mains.

6. The system of claim 1 , wherein a first harmonic frequency is 60 Hz and a third harmonic frequency is 180 Hz.

7. The system of claim 1 , wherein the RLD circuit is configured to remove a common mode voltage from a signal received from the two limb electrodes.

8. The system of claim 1 , wherein the twin-T network is configured to produce a first peak and a second peak at the output of the operational amplifier, wherein the first peak has a first center frequency located at a first harmonic frequency and the second peak has a second center frequency located at a third harmonic frequency.

Assignments (3)
RELEASE OF SECURITY INTEREST Recorded Apr 1, 2026
From: YA II PN, LTD
To: STREAMEX CORP.
Reel/Frame 074249/0365 →
SECURITY INTEREST Recorded Nov 5, 2025
From: STREAMEX CORP.
To: YA II PN, LTD.
Reel/Frame 072796/0591 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 9, 2023
From: DRAKULIC, BUDIMIR S.; FAKHAR, SINA; FOXALL, THOMAS G.; VLAJINIC, BRANISLAV
To: BIOSIG TECHONOLOGIES, INC.
Reel/Frame 062311/0895 →
Continuity (6)
Continuation 17477213 · Sep 16, 2021
Continuation 17065566 · Oct 8, 2020
Division 16718996 · Dec 18, 2019
Division 16195562 · Nov 19, 2018
Provisional Application 62669345 · May 9, 2018
Related Publication 20220240829A1 · Aug 4, 2022