IP Library Granted Patent US 12,405,256
Granted Patent B2
US 12,405,256 · App. 17/594,256 · Granted Sep 2, 2025

Chemical hydrogen peroxide indicator

Inventors: Wensheng Xia (Woodbury, MN); G. Marco Bommarito (Stillwater, MN); Naiyong Jing (St. Paul, MN)
Assignee: Solventum Intellectual Properties Company
G01N31/228B01J23/10B01J35/50G01N31/10
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Quick Facts
Patent No.
US 12,405,256
App. No.
17/594,256
Granted
Sep 2, 2025
Kind
B2
Abstract

The disclosed hydrogen peroxide indicator includes a substrate on which is disposed an indicator composition that includes at least one of a select group of indicator compounds and a catalyst. As a result of contact with hydrogen peroxide, the indicator composition changes color, even from colorless to having a visually observable color, thereby providing an indication of the presence of hydrogen peroxide.

Claims (19)

1. An indicator article for detecting hydrogen peroxide, comprising

a substrate and an indicator composition deposited thereon, wherein the indicator composition comprises:

at least one indicator compound comprising 4,4′-diamino-2,2′-stilbenedisulfonic acid (DSSA); and

a catalyst comprising cerium (IV) oxide nanoparticles;

wherein the indicator composition comprises an optical property,

wherein a visually detectable change in the optical property of the indicator composition is associated with a presence of hydrogen peroxide.

2. The indicator article of claim 1 , wherein the cerium (IV) oxide nanoparticles are present in a range from 0.0001 wt. % to 20 wt. % of the indicator composition.

3. The indicator article of claim 1 , wherein the cerium (IV) oxide nanoparticles are present in a range from 0.005 wt. % to 1 wt. % of the indicator composition.

4. The indicator article of claim 1 , wherein the catalyst accelerates a color change of the indicator composition.

5. The indicator article of claim 1 , wherein the indicator compound is colorless by visual observation when dissolved in water at a concentration of up to 0.1 wt. %, prior to exposure to hydrogen peroxide vapor.

6. The indicator article of claim 1 , wherein the hydrogen peroxide is in a sterilant vapor.

7. The indicator article of claim 1 , wherein the change in the optical property of the indicator composition is a change from having no visually detectable color to having a visually detectable color.

8. The indicator article of claim 1 , wherein the indicator composition further comprises a polymeric binder and/or a crosslinker.

9. The indicator article of claim 1 , wherein the substrate is a polyester film.

10. A method comprising:

providing the indicator article of claim 1 , comprising the indicator composition;

exposing the indicator composition to hydrogen peroxide vapor;

and visually detecting a change in an optical property of the indicator composition upon exposure to the hydrogen peroxide vapor.

11. The method of claim 10 , wherein the change in the optical property of the indicator composition is a change from colorless to having a visually detectable color.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 1, 2024
From: 3M INNOVATIVE PROPERTIES COMPANY
To: SOLVENTUM INTELLECTUAL PROPERTIES COMPANY
Reel/Frame 066430/0149 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 8, 2021
From: XIA, WENSHENG; BOMMARITO, G. MARCO; JING, NAIYONG
To: 3M INNOVATIVE PROPERTIES COMPANY
Reel/Frame 057737/0285 →
Continuity (2)
Provisional Application 62839439 · Apr 26, 2019
Related Publication 20220163496A1 · May 26, 2022
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