Granted Patent B2

US 12,396,853 · App. 17/595,919 · Granted Aug 26, 2025

Inventors: Andrea Colli (Padua, IT); Nadav Yellin (Aven Yehuda, IL); Samuel Shaolian (Newport Beach, CA); Shuki Porath (Haifa, IL)

Assignee: Valcare Medical, Inc.

A61F2/2466A61B17/00234A61F2/2457A61B2017/00243A61F2220/0016A61F2220/0041

Abstract

Claims (22)

1. A method of repairing a native chordae of a patient using an artificial chordae, the method comprising:

inserting the artificial chordae into the patient using a delivery system, wherein the artificial chordae is inserted in a non-deployed configuration;

delivering the artificial chordae to a desired position within the patient;

causing the artificial chordae to transition from the non-deployed configuration to a deployed configuration;

anchoring the artificial chordae to a myocardium of the patient via an anchoring assembly comprising an inner member comprising a barbed anchor and an outer member comprising a plurality of windows, the inner member positioned within the outer member;

attaching the artificial chordae to a leaflet of the native chordae at an attachment location via a leaflet capture subassembly coupled to the artificial chordae, the leaflet capture subassembly comprising an upper jaw and a lower jaw configured lock the leaflet between the upper jaw and the lower jaw; and

tuning the artificial chordae to a desired tension,

wherein the artificial chordae is anchored to the myocardium by deploying the barbed anchor of the inner member through the plurality of windows of the outer member and into the myocardium to secure the artificial chordae to the myocardium.

2. The method of claim 1 , further comprising delivering one or more additional devices to the desired position.

3. The method of claim 2 , wherein the one or more additional devices comprise the anchoring assembly and the leaflet capture subassembly.

4. The method of claim 2 , wherein the artificial chordae and the one or more additional devices are delivered via a single catheter.

5. The method of claim 2 , wherein the artificial chordae and the one or more additional devices are delivered in parallel within a single catheter.

6. The method of claim 2 , wherein the artificial chordae and the one or more additional devices are delivered in series within a single catheter.

7. The method of claim 2 , further comprising tuning the one or more additional devices and the artificial chordae simultaneously.

8. The method of claim 1 , further comprising installing a stress relief pad at the attachment location on the leaflet of the native chordae, wherein the stress relief pad is configured to lower stress on the leaflet and assist in healing thereof.

9. The method of claim 8 , further comprising delivering one or more additional devices to the desired position, wherein the artificial chordae and the one or more additional devices are configured to share use of the stress relief pad.

10. The method of claim 1 , wherein the artificial chordae is tuned via a tuning mechanism, the tuning mechanism comprising a pulley interfaced to a torque cable.

11. The method of claim 1 , wherein the artificial chordae is tuned via a tuning mechanism, the tuning mechanism comprising a knot in a tightening suture that is configured to be adjusted to a desired length and locked to the desired length through movement of a proximal section of the tightening suture.

12. The method of claim 1 , wherein the barbed anchor is configured to be delivered to an anchoring location in a non-deployed configuration and then deployed radially into a tissue of the myocardium to secure the artificial chordae thereto.

13. The method of claim 12 , wherein the outer member is configured to:

lock the barbed anchor in place during delivery; and

control deployment of the barbed anchor through movement of the delivery system.

Assignments (2)

Continuity (2)

References Cited (400)

Cited By (1)

US 12,642,654