IP Library Granted Patent US 12,364,385
Granted Patent B2
US 12,364,385 · App. 17/600,212 · Granted Jul 22, 2025

Imaging probe with fluid pressurization element

Inventors: Nareak Douk (Lowell, MA); Giovanni J. Ughi (Arlington, MA); Christopher C. Petroff (Groton, MA); Christopher L. Petersen (Carlisle, MA); Christopher A. Battles (Seymour, CT); R. Maxwell Flaherty (Topsfield, MA); J. Christopher Flaherty (Nottingham, NH)
Assignee: Gentuity, LLC
A61B1/00172A61B1/015A61B1/12A61B1/3137
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Quick Facts
Patent No.
US 12,364,385
App. No.
17/600,212
Granted
Jul 22, 2025
Kind
B2
Abstract

An imaging system for a patient comprises an imaging probe. The imaging probe comprises: an elongate shaft for insertion into the patient and comprising a proximal end, a distal portion, and a lumen extending between the proximal end and the distal portion; a rotatable optical core comprising a proximal end and a distal end, and at least a portion of the rotatable optical core is positioned within the lumen of the elongate shaft; an optical assembly positioned proximate the distal end of the rotatable optical core, the optical assembly configured to direct light to tissue and collect reflected light from the tissue; a damping fluid positioned between the elongate shaft and the rotatable optical core and configured to reduce non-uniform rotation of the optical assembly; and a fluid pressurization element configured to increase the pressure of the damping fluid to reduce the presence of bubbles proximate the optical assembly.

Claims (69)

1. An imaging system for a patient comprising:

an imaging probe, comprising:

an elongate shaft comprising a proximal end, a distal portion, and a lumen extending between the proximal end and the distal portion;

a rotatable optical core comprising a proximal end and a distal end, wherein at least a portion of the rotatable optical core is positioned within the lumen of the elongate shaft;

an optical assembly positioned proximate the distal end of the rotatable optical core, the optical assembly configured to direct light to tissue and collect reflected light from the tissue;

a damping fluid positioned between the elongate shaft and the rotatable optical core and configured to reduce non-uniform rotation of the optical assembly; and

a fluid pressurization element configured to increase the pressure of the damping fluid to reduce the presence of bubbles proximate the optical assembly;

an imaging assembly constructed and arranged to optically couple to the imaging probe, the imaging assembly configured to emit light into the imaging probe and receive the reflected light collected by the optical assembly;

wherein the damping fluid comprises a fluid with high surface tension configured to reduce bubble formation.

2. The system as claimed in claim 1 , wherein the fluid pressurization element is configured to reduce bubble formation.

3. The system as claimed in claim 1 , wherein the fluid pressurization element is configured to reduce the size of one or more bubbles.

4. The system as claimed in claim 1 , wherein the system comprises an optical beam path, and wherein the fluid pressurization element is configured to propel one or more bubbles to a location remote from the optical beam path.

5. The system as claimed in claim 1 , wherein the fluid pressurization element is configured to create a pressure gradient within the damping fluid.

6. The system as claimed in claim 1 , wherein the fluid pressurization element is configured to generate a pressure of the damping fluid of at least: 3.6 psi; 5.0 psi; 10 psi; 15 psi; 20 psi; 30 psi; 40 psi; 75 psi; 100 psi; 125 psi; and/or 150 psi.

7. The system as claimed in claim 1 , wherein the fluid pressurization element is configured to increase the pressure of the damping fluid when the rotatable optical core is rotated.

8. The system according to claim 7 , wherein the fluid pressurization element comprises a helical projection that radially extends from the rotatable optical core.

9. The system as claimed in claim 1 , wherein the fluid pressurization element comprises a first fluid pressurization element and a second fluid pressurization element, and wherein the second fluid pressurization element is positioned proximal to the first fluid pressurization element.

10. The system according to claim 9 , wherein the second fluid pressurization element is configured to prime the first fluid pressurization element when rotated.

11. The system as claimed in claim 1 , wherein the fluid pressurization element comprises a material selected from the group consisting of:

metal; plastic; stainless steel; nickel-titanium alloy; nylon; polyether ether ketone;

polyimide; and combinations thereof.

12. The system as claimed in claim 1 , wherein the rotatable optical core comprises a diameter D 1 , wherein the elongate shaft lumen comprises a diameter D 2 , wherein the fluid pressurization element extends from the rotatable optical core with a radial height H 1 , and wherein H 1 comprises at least 5% and/or no more than 95% of half the difference between D 1 and D 2 .

13. The system as claimed in claim 1 , wherein the rotatable optical core comprises a diameter D 1 , wherein the elongate shaft lumen comprises a diameter D 2 , wherein the fluid pressurization element extends from the rotatable optical core with a radial height H 1 , wherein a clearance C 1 comprises one half the difference between D 1 and D 2 minus H 1 , and wherein clearance C 1 comprises a length of no more than 100 μm and/or no more than 75 um.

14. The system as claimed in claim 1 , wherein the damping fluid comprises a shear-thinning fluid.

15. The system as claimed in claim 1 , wherein the damping fluid comprises a low viscosity fluid configured to reduce bubble formation.

16. The system according to claim 15 , wherein the damping fluid comprises a fluid with a viscosity of no more than 1000 centipoise.

17. The system according to claim 1 , wherein the damping fluid comprises a fluid with a surface tension of at least 40 dynes/cm.

18. The system as claimed in claim 1 , wherein the imaging probe comprises a distal portion with a diameter of no more than 0.020″.

19. The system according to claim 18 , wherein the imaging probe distal portion comprises a diameter of no more than 0.016″.

20. The system as claimed in claim 1 , wherein the imaging probe further includes a sealing element in a distal portion of the elongate shaft.

21. An imaging system for a patient comprising:

an imaging probe, comprising:

an elongate shaft comprising a proximal end, a distal portion, and a lumen extending between the proximal end and the distal portion;

a rotatable optical core comprising a proximal end and a distal end, wherein at least a portion of the rotatable optical core is positioned within the lumen of the elongate shaft;

an optical assembly positioned proximate the distal end of the rotatable optical core, the optical assembly configured to direct light to tissue and collect reflected light from the tissue;

a damping fluid positioned between the elongate shaft and the rotatable optical core and configured to reduce non-uniform rotation of the optical assembly; and

a fluid pressurization element configured to increase the pressure of the damping fluid to reduce the presence of bubbles proximate the optical assembly;

an imaging assembly constructed and arranged to optically couple to the imaging probe, the imaging assembly configured to emit light into the imaging probe and receive the reflected light collected by the optical assembly;

wherein the fluid pressurization element is configured to increase the pressure of the damping fluid intermittently, and

wherein the fluid pressurization element is configured to increase the pressure of the damping fluid for discrete time periods of no more than five seconds.

22. An imaging system for a patient comprising:

an imaging probe, comprising:

an elongate shaft comprising a proximal end, a distal portion, and a lumen extending between the proximal end and the distal portion;

a rotatable optical core comprising a proximal end and a distal end, wherein at least a portion of the rotatable optical core is positioned within the lumen of the elongate shaft;

an optical assembly positioned proximate the distal end of the rotatable optical core, the optical assembly configured to direct light to tissue and collect reflected light from the tissue;

a damping fluid positioned between the elongate shaft and the rotatable optical core and configured to reduce non-uniform rotation of the optical assembly; and

a fluid pressurization element configured to increase the pressure of the damping fluid to reduce the presence of bubbles proximate the optical assembly;

an imaging assembly constructed and arranged to optically couple to the imaging probe, the imaging assembly configured to emit light into the imaging probe and receive the reflected light collected by the optical assembly;

wherein the fluid pressurization element is adhesively attached to the rotatable optical core.

23. An imaging system for a patient comprising:

an imaging probe, comprising:

an elongate shaft comprising a proximal end, a distal portion, and a lumen extending between the proximal end and the distal portion;

a rotatable optical core comprising a proximal end and a distal end, wherein at least a portion of the rotatable optical core is positioned within the lumen of the elongate shaft;

an optical assembly positioned proximate the distal end of the rotatable optical core, the optical assembly configured to direct light to tissue and collect reflected light from the tissue;

a damping fluid positioned between the elongate shaft and the rotatable optical core and configured to reduce non-uniform rotation of the optical assembly; and

a fluid pressurization element configured to increase the pressure of the damping fluid to reduce the presence of bubbles proximate the optical assembly:

an imaging assembly constructed and arranged to optically couple to the imaging probe, the imaging assembly configured to emit light into the imaging probe and receive the reflected light collected by the optical assembly;

wherein the fluid pressurization element is formed into the rotatable optical core, and;

wherein the system is formed onto the rotatable optical core via deposition and/or three-dimensional (3D) printing.

24. An imaging system for a patient comprising:

an imaging probe, comprising:

an elongate shaft comprising a proximal end, a distal portion, and a lumen extending between the proximal end and the distal portion;

a rotatable optical core comprising a proximal end and a distal end, wherein at least a portion of the rotatable optical core is positioned within the lumen of the elongate shaft;

an optical assembly positioned proximate the distal end of the rotatable optical core, the optical assembly configured to direct light to tissue and collect reflected light from the tissue;

a damping fluid positioned between the elongate shaft and the rotatable optical core and configured to reduce non-uniform rotation of the optical assembly; and

a fluid pressurization element configured to increase the pressure of the damping fluid to reduce the presence of bubbles proximate the optical assembly:

an imaging assembly constructed and arranged to optically couple to the imaging probe, the imaging assembly configured to emit light into the imaging probe and receive the reflected light collected by the optical assembly;

wherein the damping fluid comprises a static viscosity of at least 500 centipoise, and

wherein the damping fluid comprises a static viscosity to shear viscosity ratio of at least 1.2:1 and/or no more than 100:1.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 18, 2021
From: DOUK, NAREAK; UGHI, GIOVANNI; PETROFF, CHRISTOPHER; PETERSEN, CHRISTOPHER; BATTLES, CHRISTOPHER A.; FLAHERTY, R. MAXWELL; FLAHERTY, J. CHRISTOPHER
To: GENTUITY, LLC.
Reel/Frame 057821/0279 →
Continuity (5)
Provisional Application 63017258 · Apr 29, 2020
Provisional Application 62906353 · Sep 26, 2019
Provisional Application 62850945 · May 21, 2019
Provisional Application 62840450 · Apr 30, 2019
Related Publication 20220142462A1 · May 12, 2022
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