ANTIMICROBIAL WIPES

1 . A pre-loaded wipe comprising:

a plurality of fibers having a denier value of less than about 1.0; and

an antimicrobial composition comprising a cationic antiseptic compound selected from a bispyridine, a biguanide, a bisbiguanide, a polymeric biguanide, a salt thereof, and a combinations thereof.

wherein the cationic antimicrobial composition is distributed throughout the plurality of fibers.

2 . The pre-loaded wipe of claim 1 , wherein the cationic antiseptic compound is selected from octenidine dihydrochloride, polyhexamethylene biguanide (PHMB), chlorhexidine gluconate (CHG), and a combination thereof.

3 . The pre-loaded wipe of claim 1 , the antimicrobial composition further comprising a first surfactant characterized by an HLB value of less than about 10,

wherein the first surfactant is selected from a polyethylene glycol (PEG) alkyl ester, an alkyl ester, an alkyl ether, an alkyl amide and mixtures and a combinations thereof,

wherein the first surfactant comprises an alkyl group having 8 to 22 carbon atoms.

4 . The pre-loaded wipe as claimed in claim 3 , the cationic antimicrobial composition further comprising a second surfactant characterized by an HLB value of about 10 to about 14,

wherein the second surfactant is selected from a polyethylene glycol (PEG) alkyl ester,

wherein the second surfactant is different from the first surfactant,

wherein the second surfactant comprises an alkyl group having 17 to 21 carbon atoms.

5 . The pre-loaded wipe of claim 4 , the cationic antimicrobial composition further comprising a third surfactant characterized by an HLB value in a range from about 14 to about 18, wherein the third surfactant is a PEG compound chosen from PEG alkyl esters, PEG alkyl ethers, PEG alkyl amides, and mixtures and combinations thereof, and wherein the third surfactant is different from the first surfactant.

6 . The pre-loaded wipe of claim 1 , the cationic antimicrobial composition further comprising a surfactant system, the surfactant system comprising a PEG alkyl ester having an HLB value in a range from about 8 to about 14; and wherein the PEG alkyl ester is a reaction product of a PEG and a C8 to C22 fatty acid.

7 . The pre-loaded wipe of claim 1 , wherein at least 50 wt. % of the cationic antiseptic compound is released from the plurality of fibers upon wiping the pre-loaded wipe over a treatment site chosen from skin, hair, mucosae, wounds, and body cavities.

8 - 11 . (canceled)

12 . A method of disinfecting a treatment site chosen from skin, hair, mucosae, wounds, and body cavities, the method comprising:

providing a pre-loaded wipe of claim 1 ; and

contacting the pre-loaded wipe to the treatment site such that the cationic antimicrobial composition from the pre-loaded wipe is distributed to the treatment site in an amount effective to kill a microorganism chosen from bacteria, fungi, viruses, and mixtures and combinations thereof.

13 . The method of claim 12 , wherein the cationic antiseptic compound is chosen from bispyridines, biguanides, bisbiguanides, polymeric biguanides, salts thereof, and mixtures and combinations thereof.

14 . The method of claim 13 , wherein the cationic antiseptic is chosen from octenidine dihydrochloride, polyhexamethylene biguanide (PHMB), and chlorhexidine gluconate (CHG), and combinations thereof.

15 . The method of claim 12 , the cationic antimicrobial composition further comprising a surfactant system, the surfactant system comprising a surfactant selected from

a first surfactant characterized by an HLB value of less than about 10,

a second surfactant different from the first surfactant, the second surfactant characterized by an HLB value in a range from about 10 to about 14,

a third surfactant different from both the first surfactant and the second surfactant, the third surfactant characterized by an HLB value in a range from about 14 to about 18, and

a combination thereof.

16 . The method of claim 12 , further comprising:

wiping the pre-loaded wipe over the treater site.

17 . The method of claim 12 , wherein the treatment site is porous and the method further comprising:

penetrating the cationic antimicrobial composition into the porous treatment site.

18 . The method of claim 12 , releasing at least 50 wt. % of the cationic antiseptic compound from the pre-loaded wipe to the treatment site.

19 . A pre-loaded wipe comprising:

a plurality of fibers having a denier value of less than about 1.0; and

an antimicrobial composition comprising:

a cationic antiseptic compound selected from a bispyridine, a biguanide, a bisbiguanide, a polymeric biguanide, a salt thereof, and a combination thereof, and

a surfactant system comprising a first surfactant characterized by an HLB value of less than about 10,

wherein the cationic antimicrobial composition is distributed throughout the plurality of fibers.

20 . The pre-loaded wipe of claim 19 , further comprising:

a second surfactant different from the first surfactant, the second surfactant characterized by an HLB value in a range from about 10 to about 14.

21 . The pre-loaded wipe of claim 19 , further comprising:

a second surfactant different from the first surfactant, the second surfactant characterized by an HLB value in a range from about 10 to about 14, and

a third surfactant different from both the first surfactant and the second surfactant, the third surfactant characterized by an HLB value in a range from about 14 to about 18.