Patent Application
Utility
PCT National Stage
App. No. 17/619,633
· Confirmation No. 8231
DELIVERY OF OLIGONUCLEOTIDES TO THE STRIATUM
Inventors:
Jayaprakash K. Nair, Martin Maier, Vasant Jadhav, Stuart Milstein, Kirk Brown, Rubina G. Parmar, Kallanthottathil G. Rajeev, Muthiah Manoharan, Alexander V. Kel'in, Muthusamy Jayaraman, Klaus Charisse, Adam Castoreno, Christopher S. Theile, Kevin Fitzgerald
Applicant:
ALNYLAM PHARMACEUTICALS, INC.
Final Rejection Mailed
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| 2026-06-16 | CTFR |
Final Rejection | 13 | View | |
| 2026-06-16 | SRFW |
Search information including classification, databases and other search related notes | 2 | View | |
| 2026-06-16 | SRNT |
Examiner's search strategy and results | 4 | View | |
| 2026-06-16 | SRNT |
Examiner's search strategy and results | 21 | View | |
| 2026-02-19 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2025-10-02 | DRW |
Drawings-only black and white line drawings | 26 | View | |
| 2025-10-02 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2025-10-02 | A... |
Amendment/Request for Reconsideration-After Non-Final Rejection | 1 | View | |
| 2025-10-02 | SPEC |
Specification | 1 | View | |
| 2025-10-02 | CLM |
Claims | 4 | View | |
| 2025-10-02 | REM |
Applicant Arguments/Remarks Made in an Amendment | 11 | View | |
| 2025-10-02 | DRW.SUPP |
Drawings-black and white line and/or other drawings | — | View | |
| 2025-10-02 | SCORE |
Placeholder sheet indicating presence of supplemental content in Supplemental Complex Repository for Examiners(SCORE) | 1 | View | |
| 2025-10-02 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2025-07-03 | CTNF |
Non-Final Rejection | 15 | View | |
| 2025-07-03 | 892 |
List of references cited by examiner | 1 | View | |
| 2025-07-03 | SRFW |
Search information including classification, databases and other search related notes | 1 | View | |
| 2025-07-03 | FOR |
Foreign Reference | 114 | View | |
| 2025-07-03 | SRNT |
Examiner's search strategy and results | 5 | View | |
| 2025-07-03 | 1449 |
List of References cited by applicant and considered by examiner | 4 | View | |
| 2025-07-03 | SRNT |
Examiner's search strategy and results | 2 | View | |
| 2025-07-03 | BIB |
Bibliographic Data Sheet | 2 | View | |
| 2025-07-03 | 1449 |
List of References cited by applicant and considered by examiner | 4 | View | |
| 2025-05-30 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2025-05-30 | ELC. |
Response to Election / Restriction Filed | 1 | View | |
| 2025-05-30 | CLM |
Claims | 7 | View | |
| 2025-05-30 | REM |
Applicant Arguments/Remarks Made in an Amendment | 4 | View | |
| 2025-03-31 | CTRS |
Requirement for Restriction/Election | 7 | View | |
| 2025-03-31 | 892 |
List of references cited by examiner | 1 | View | |
| 2024-01-17 | N570 |
Communication - Re: Power of Attorney (PTOL-308) | 1 | View | |
| 2024-01-17 | N570 |
Communication - Re: Power of Attorney (PTOL-308) | 1 | View | |
| 2024-01-04 | PA.. |
Power of Attorney | 2 | View | |
| 2024-01-04 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2023-11-16 | FOR |
Foreign Reference | 48 | View | |
| 2023-11-16 | FOR |
Foreign Reference | 271 | View | |
| 2023-11-16 | IDS |
Information Disclosure Statement (IDS) Form (SB08) | 4 | View | |
| 2023-11-16 | N417 |
Electronic Filing System Acknowledgment Receipt | 3 | View | |
| 2023-11-16 | FOR |
Foreign Reference | 199 | View | |
| 2023-11-16 | FOR |
Foreign Reference | 308 | View | |
| 2023-03-07 | N570 |
Communication - Re: Power of Attorney (PTOL-308) | 1 | View | |
| 2023-03-02 | MFEE.C.AD.PC |
Change of Address via Patent Center | 1 | View | |
| 2023-03-02 | C.AD.PC |
Change of Address via Patent Center | 1 | View | |
| 2023-02-28 | PA.. |
Power of Attorney | 2 | View | |
| 2023-02-28 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2022-09-29 | NTC.PUB |
Notice of Publication | 1 | View | |
| 2022-06-17 | WCLM |
Claims Worksheet (PTO-2022) | 2 | View | |
| 2022-06-17 | APP.FILE.REC |
Filing Receipt | 4 | View | |
| 2022-06-17 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2022-06-17 | M903 |
Notice of Designated Office (DO) / Elected Office (EO) Acceptance Mailed | 2 | View | |
| 2021-12-17 | CRFE |
Sequence Listing in Computer Readable Format, No errors found | 22 | View | |
| 2021-12-16 | DRW |
Drawings-only black and white line drawings | 26 | View | |
| 2021-12-16 | CLM |
Claims | 13 | View | |
| 2021-12-16 | SPEC |
Specification | 278 | View | |
| 2021-12-16 | ABST |
Abstract | 2 | View | |
| 2021-12-16 | FRPR |
Certified Copy of Foreign Priority Application | 311 | View | |
| 2021-12-16 | P.306 |
PCT/IB/306 - Notification of the Recording of a Change | 1 | View | |
| 2021-12-16 | P.306 |
PCT/IB/306 - Notification of the Recording of a Change | 1 | View | |
| 2021-12-16 | SEQ.TXT |
Sequence Listing (Text File) | 1 | View | |
| 2021-12-16 | IDS |
Information Disclosure Statement (IDS) Form (SB08) | 4 | View | |
| 2021-12-16 | REF.OTHER |
Other reference-Patent/Application/Search Documents | 18 | View | |
| 2021-12-16 | FOR |
Foreign Reference | 211 | View | |
| 2021-12-16 | CRFS |
CRF Statement that Sequence Listing text file (CRF) and paper/pdf Sequence Listing are the same | 1 | View | |
| 2021-12-16 | WFEE |
Fee Worksheet (SB06) | 2 | View | |
| 2021-12-16 | N417 |
Electronic Filing System Acknowledgment Receipt | 6 | View | |
| 2021-12-16 | OATH |
Oath or Declaration filed | 2 | View | |
| 2021-12-16 | OATH |
Oath or Declaration filed | 2 | View | |
| 2021-12-16 | OATH |
Oath or Declaration filed | 2 | View | |
| 2021-12-16 | OATH |
Oath or Declaration filed | 2 | View | |
| 2021-12-16 | OATH |
Oath or Declaration filed | 2 | View | |
| 2021-12-16 | OATH |
Oath or Declaration filed | 2 | View | |
| 2021-12-16 | OATH |
Oath or Declaration filed | 1 | View | |
| 2021-12-16 | OATH |
Oath or Declaration filed | 1 | View | |
| 2021-12-16 | OATH |
Oath or Declaration filed | 2 | View | |
| 2021-12-16 | OATH |
Oath or Declaration filed | 1 | View | |
| 2021-12-16 | OATH |
Oath or Declaration filed | 2 | View | |
| 2021-12-16 | OATH |
Oath or Declaration filed | 1 | View | |
| 2021-12-16 | OATH |
Oath or Declaration filed | 1 | View | |
| 2021-12-16 | OATH |
Oath or Declaration filed | 1 | View | |
| 2021-12-16 | TRNA |
Transmittal of New Application | 4 | View | |
| 2021-12-16 | ADS |
Application Data Sheet | 12 | View | |
| 2021-12-16 | A.PE |
Preliminary Amendment | 1 | View | |
| 2021-12-16 | SPEC |
Specification | 1 | View | |
| 2021-12-16 | CLM |
Claims | 13 | View | |
| 2021-12-16 | REM |
Applicant Arguments/Remarks Made in an Amendment | 2 | View | |
| 2021-12-16 | 371P |
Documents submitted with 371 (National Stage) Applications | 2 | View | |
| 2021-12-16 | P.N.101.CONV |
PCT/RO/101 - Request form for new International Application - Conventional | 7 | View | |
| 2021-12-16 | 371P |
Documents submitted with 371 (National Stage) Applications | 2 | View |
Inventors
Jayaprakash K. Nair
Cambridge, MA
Martin Maier
Cambridge, MA
Vasant Jadhav
Cambridge, MA
Stuart Milstein
Cambridge, MA
Kirk Brown
Cambridge, MA
Rubina G. Parmar
Cambridge, MA
Kallanthottathil G. Rajeev
Cambridge, MA
Muthiah Manoharan
Cambridge, MA
Alexander V. Kel'in
Cambridge, MA
Muthusamy Jayaraman
Cambridge, MA
Klaus Charisse
Cambridge, MA
Adam Castoreno
Cambridge, MA
Christopher S. Theile
Cambridge, MA
Kevin Fitzgerald
Cambridge, MA
Attorneys & Agents of Record
Classification
USPC
514/44A
A61K9/0085
C12N2310/14
C12N2310/312
C12N2310/314
C12N2310/315
C12N2310/321
C12N2310/322
C12N2310/3231
C12N2310/3515
C12N2320/32
C12N2310/3521
C12N2310/3533
C12N15/113
A61P25/28
A61P35/00
Prosecution
- Examiner
- MCKILLOP, JOHN CHARLES
- Art Unit
- 1637
- Customer No.
- 103542
- Docket No.
- 121301-23402
- Confirmation No.
- 8231
Publication
- Pub. No.
- US20220307024A1
- Pub. Date
- 2022-09-29
SECURITY INTEREST
Recorded 2025-10-01
from
CASTORENO, ADAM,
MANOHARAN, MUTHIAH,
FITZGERALD, KEVIN,
MAIER, MARTIN,
BROWN, KIRK,
JAYARAMAN, MUTHUSAMY,
CHARISSE, KLAUS,
NAIR, JAYAPRAKASH K.,
JADHAV, VASANT,
MILSTEIN, STUART,
RAJEEV, KALLANTHOTTATHIL G.,
THEILE, CHRISTOPHER S.,
PARMAR, RUBINA G.,
KEL'IN, ALEXANDER V.
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded 2023-12-22
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Quick Facts
- App. No.
- 17/619,633
- Filed
- 2021-12-16
- Pub. No.
- US20220307024A1
- Examiner
- MCKILLOP, JOHN CHARLES
- Art Unit
- 1637
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