Method for vaccinating avians against reovirus

1 . A method for vaccinating an avian against a reovirus or an associated disease, comprising administering to the avian a composition comprising at least one inactivated avian reovirus and an adjuvant comprising a lipophile and a polymer of acrylic or methacrylic acid, wherein the composition is administered to the avian between day 1 and day 14 of age.

2 . The method of claim 1 , wherein the composition is administered to the avian between day 1 and day 7 of age.

3 . The method of claim 2 , wherein the composition is administered to the avian within 24 hours post-hatching.

4 . The method of claim 1 , wherein the composition comprises at least two distinct inactivated avian reoviruses.

5 . The method of claim 1 , wherein the at least one inactivated avian reovirus is an avian pathogenic reovirus strain.

6 . The method of claim 1 , wherein the inactivated reovirus is selected from inactivated strains S1, S2, S3, S1133, 2408, SS412, 2177, 1703, 1733, 1123, ERS-1 and 3005.

7 . The method of claim 1 , wherein the composition comprises inactivated reovirus strains S1, S2 and S3.

8 . The method of claim 1 , wherein the composition is administered at a dose from 10 3 TCID 50 to 10 9 TCID 50 of antigenic material per avian.

9 . The method of claim 1 , wherein the lipophile is selected from the group consisting of medium chain EP triglycerides, medium chain triglycerides NF, medium chain fatty acid triglyceride JPE, caprylic/capric triglyceride, and combinations thereof.

10 . The method of claim 1 , wherein the adjuvant further comprises at least one compound selected from saline, sterol, alcohol, saponin, sodium hydroxide, and any combination thereof.

11 . The method of claim 1 , wherein the avian is a poultry.

12 . The method of claim 1 , wherein a further administration with a composition comprising at least one avian reovirus antigenic material administered to the avian between 6 to 18 weeks of age.

13 . The method of claim 12 , wherein the avian reovirus in the compositions is derived from a similar or a different avian reovirus strain.

14 . A method for inducing a protective immune response in an avian against at least one reovirus, comprising administering to said avian a vaccine comprising at least one antigenic material comprising at least one inactivated avian reovirus and an adjuvant comprising a lipophile and a polymer of acrylic or methacrylic acid, wherein the vaccine is administered to the avian between day 1 and day 14 of age.

15 . The method of claim 11 , wherein the poultry is a chicken.

16 . The method of claim 10 , wherein the sterol is cholesterol.

17 . The method of claim 10 , wherein the alcohol is selected from ethanol, isopropanol, butanol and combinations thereof.