IP Library Granted Patent US 12,290,684
Granted Patent B2
US 12,290,684 · App. 17/642,621 · Granted May 6, 2025

Wearable system for intra-ear sensing and stimulating

Inventors: Tam Vu (Boulder, CO); Robin Deterding (Boulder, CO); Farnoush Banaei-Kashani (Centennial, CO); Nhat Pham (Boulder, CO); Nam Ngoc Bui (Broomfield, CO)
Assignee: THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE
A61N1/36036A61B5/02438A61B5/369A61B5/389A61B5/398A61B5/4094A61B5/6817A61M21/02A61N1/0541
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Quick Facts
Patent No.
US 12,290,684
App. No.
17/642,621
Granted
May 6, 2025
Kind
B2
Abstract

A computer system for intra-ear sensing and stimulating receives, health data, from an earbud sensor. The system repeatedly calculates an exponential moving average (EMA) of a moving window for the received health data. The system compares each calculated exponential moving average with a lower threshold value and an upper threshold value. The upper threshold value and the lower threshold value are determined based, at least in part, upon a saturation level associated within an amplifier performing the adaptive gain control. When the calculated exponential moving average is larger than the upper threshold, the system decreases a gain associated with the amplifier. When the calculated exponential moving average is smaller than the lower threshold, the system increases a gain associated with the amplifier.

Claims (37)

1. A system for intra-ear sensing and stimulating, comprising:

an earbud sensor comprising:

a shape and size that is configured to extend, at least partially, into an ear canal of a user,

an in-ear electrical electrode, wherein the in-ear electrical electrode comprises an active electrode, and

a three-fold cascaded amplifier configured to amplify a signal generated by the in-ear electrical electrode, wherein the three-fold cascaded amplifier comprises a buffering stage, a feed forward differential preamplifying stage, and an adaptive amplifying stage;

one or more processors; and

one or more physical computer-readable storage media having stored thereon executable instructions that when executed by the e one or more processors configure the system to perform at least the following:

repeatedly calculate an exponential moving average (EMA) of a moving window for health information;

compare each calculated exponential moving average with a lower threshold value and an upper threshold value, wherein the upper threshold value and the lower threshold value are determined based, at least in part, upon a saturation level associated within the three-fold cascaded amplifier performing an adaptive gain control;

when the calculated exponential moving average is larger than the upper threshold value, decrease a gain associated with the three-fold cascaded amplifier;

when the calculated exponential moving average is smaller than the lower threshold value, increase a gain associated with the three-fold cascaded amplifier; and

wherein the earbud sensor is configured to non-invasively measure various health information, including one or more of brain waves (EEG and electromagnetic fields generated by neural activities), eyes movements (EOG), facial muscle activities (EMG), heart rate, breathing rate, swallowing sound, ear canal pictures, and head motion from inside human ears.

2. The system as recited in claim 1 , wherein the system is executed in various potential applications in daily life, including one or more of continuous epilepsy monitoring and suppressing, sleep improvements, diagnosing ear infection, memory enhancement, or drug calibration.

3. The system as recited in claim 1 , wherein the earbud sensor is detachable from a base member such that the earbud sensor can be replaced.

4. The system as recited in claim 1 , wherein the in-ear electrical electrode comprises an array of electrodes.

5. The system as recited in claim 1 , wherein the in-ear electrical electrode comprises an individual electrode.

6. A computer-implemented method, executed on one or more processors, for intra-ear sensing and stimulating, the method comprising:

receiving, health data, from an earbud sensor, the earbud sensor comprising:

a shape and size that is configured to extend, at least partially, into an ear canal of a user,

an in-ear electrical electrode, wherein the in-ear electrical electrode comprises an active electrode, and

a three-fold cascaded amplifier configured to amplify a signal generated by the in-ear electrical electrode, wherein a first stage and a second stage of the three-fold cascaded amplifier are implemented in earpieces of the earbud sensor and a third stage of the three-fold cascaded amplifier is implemented on a sensing circuit of the earbud sensor;

repeatedly calculating an exponential moving average (EMA) of a moving window for the received health data;

comparing each calculated exponential moving average with a lower threshold value and an upper threshold value, wherein the upper threshold value and the lower threshold value are determined based, at least in part, upon a saturation level associated within the three-fold cascaded amplifier performing an adaptive gain control;

when the calculated exponential moving average is larger than the upper threshold value, decreasing a gain associated with the three-fold cascaded amplifier; and

when the calculated exponential moving average is smaller than the lower threshold value, increasing a gain associated with the three-fold cascaded amplifier.

7. The computer-implemented method as recited in claim 6 , wherein the earbud sensor is detachable from a base member such that the earbud sensor can be replaced.

8. The computer-implemented method as recited in claim 6 , wherein the in-ear electrical electrode comprises an array of electrodes.

9. The computer-implemented method as recited in claim 6 , wherein the in-ear electrical electrode comprises an individual electrode.

10. A computer-readable media comprising one or more physical computer-readable storage media having stored thereon computer-executable instructions that, when executed at a processor, cause a computer system to perform a method for intra-ear sensing and stimulating, the method comprising:

receiving, health data, from an earbud sensor, the earbud sensor comprising:

a shape and size that is configured to extend, at least partially, into an ear canal of a user,

an in-ear electrical electrode, wherein the in-ear electrical electrode comprises an active electrode, and

a three-fold cascaded amplifier configured to amplify a signal generated by the in-ear electrical electrode, wherein a first stage and a second stage of the three-fold cascaded amplifier are implemented in earpieces of the earbud sensor and a third stage of the three-fold cascaded amplifier is implemented on a sensing circuit of the earbud sensor;

comparing each calculated exponential moving average with a lower threshold value and an upper threshold value, wherein the upper threshold value and the lower threshold value are determined based, at least in part, upon a saturation level associated within an three-fold cascaded amplifier performing an adaptive gain control;

when the calculated exponential moving average is larger than the upper threshold value, decreasing a gain associated with the three-fold cascaded amplifier; and

when the calculated exponential moving average is smaller than the lower threshold value, increasing a gain associated with the three-fold cascaded amplifier.

11. The computer-readable media as recited in claim 10 , wherein the earbud sensor is detachable from a base member such that the earbud sensor can be replaced.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 11, 2022
From: VU, TAM; DETERDING, ROBIN; BANAEI-KASHANI, FARNOUSH; PHAM, NHAT; BUI, NAM NGOC
To: THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE
Reel/Frame 059246/0048 →
Continuity (2)
Provisional Application 62900187 · Sep 13, 2019
Related Publication 20220339444A1 · Oct 27, 2022
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