IP Library Granted Patent US 11,712,581
Granted Patent B2
US 11,712,581 · App. 17/645,887 · Granted Aug 1, 2023

Radiation treatment planning and delivery for moving targets in the heart

Inventors: Thilaka Sumanaweera (Los Altos, CA); Patrick Maguire (Portola Valley, CA); Edward Gardner (San Jose, CA)
Assignee: VARIAN MEDICAL SYSTEMS, INC.
A61N5/1037A61N5/1031A61B5/318A61B6/032A61B6/503A61B6/5235A61B6/5294A61N5/1039A61N5/1049A61N5/1067A61N5/1068A61N5/1077A61N2005/1061
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Quick Facts
Patent No.
US 11,712,581
App. No.
17/645,887
Granted
Aug 1, 2023
Kind
B2
Abstract

Methods and systems are disclosed for radiating a moving object. The method may comprise acquiring a plurality of indicators of the phase of a physiological cycle of a patient and a plurality of images of the patient that include a target. Each image may be taken at a different phase of the physiological cycle and may be registered to the phase at which the image was taken. The method may also include identifying the target in each of the plurality of images, calculating a dose of radiation required to treat the target, calculating the number, orientation, and dwell time of one or more radiation beams required to deliver the calculated required dose of radiation to the target, and calculating a position of each of the one or more radiation beams required to achieve the calculated orientation. Each position may be a function of the phase of the physiological cycle to which each of the plurality of images is registered.

Claims (37)

1. A method of radiating of a moving object, comprising:

acquiring a baseline set of a plurality of indicators of a phase of a physiological cycle of a patient;

acquiring a calculated position of each of one or more radiation beams required to treat a target in the patient, wherein each of the positions is a function of the phase of the physiological cycle;

identifying a current phase of the physiological cycle of the patient;

registering the current phase of the physiological cycle of the patient to the baseline set of the plurality of indicators of the phase of a physiological cycle of the patient;

positioning each of the one or more radiation beams according to the registration; and

delivering a dose of radiation.

2. The method of claim 1 , further comprising:

acquiring a baseline set of a plurality of images of the patient that include the target, each image taken at a different phase of the physiological cycle and registered to the phase at which the image was taken;

acquiring a current image of the patient that includes the target, wherein the current image of the patient is taken at the current phase of the physiological cycle;

registering the current image of the patient to an image in the baseline set of a plurality of images of the patient that occurred at the same phase of the physiological cycle as the current phase of the physiological cycle;

updating the calculated position of each of one or more radiation beams required to treat a target in the patient based on the registration.

3. The method of claim 2 , further comprising:

calculating a dose of radiation already delivered to the tissues of the patient based on the registration.

4. The method of claim 3 , further comprising:

comparing the calculated dose of radiation already delivered to a dose of radiation required to treat the target.

5. The method of claim 2 , wherein the current image is acquired via CT scan, MRI, PET scan, X-Ray, or ultrasound.

6. The method of claim 1 , wherein the physiological cycle is a heartbeat cycle or a respiratory cycle.

7. The method of claim 6 , wherein the heartbeat cycle is determined by EKG.

8. A radiation treatment planning system comprising at least one computing device, the at least one computing device configured to:

acquire a baseline set of a plurality of indicators of a phase of a physiological cycle of a patient;

acquire a calculated position of each of one or more radiation beams required to treat a target in the patient, wherein each of the positions is a function of the phase of the physiological cycle;

identify a current phase of the physiological cycle of the patient;

register the current phase of the physiological cycle of the patient to the baseline set of the plurality of indicators of the phase of a physiological cycle of the patient; and

position each of the one or more radiation beams according to the registration.

9. The system of claim 8 , wherein the at least one computing device is further configured to:

acquire a baseline set of a plurality of images of the patient that include the target, each image taken at a different phase of the physiological cycle and registered to the phase at which the image was taken;

acquire a current image of the patient that includes the target, wherein the current image of the patient is taken at the current phase of the physiological cycle;

register the current image of the patient to an image in the baseline set of a plurality of images of the patient that occurred at the same phase of the physiological cycle as the current phase of the physiological cycle;

update the calculated position of each of one or more radiation beams required to treat a target in the patient based on the registration.

10. The system of claim 9 , wherein the at least one computing device is further configured to:

calculate a dose of radiation already delivered to the tissues of the patient based on the registration.

11. The system of claim 10 , wherein the at least one computing device is further configured to:

compare the calculated dose of radiation already delivered to a dose of radiation required to treat the target.

12. The system of claim 9 , wherein the current image is acquired via CT scan, MRI, PET scan, X-Ray, or ultrasound.

13. The system of claim 8 , wherein the physiological cycle is a heartbeat cycle or a respiratory cycle.

14. The system of claim 13 , wherein the heartbeat cycle is determined by EKG.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 23, 2021
From: SUMANAWEERA, THILAKA; MAGUIRE, PATRICK; GARDNER, ED
To: CYBERHEART, INC.
Reel/Frame 058472/0926 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 23, 2021
From: CYBERHEART, INC.
To: VARIAN MEDICAL SYSTEMS, INC.
Reel/Frame 058974/0208 →
Continuity (9)
Division 17038912 · Sep 30, 2020
Continuation 16194964 · Nov 19, 2018
Continuation 15940783 · Mar 29, 2018
Continuation 14624056 · Feb 17, 2015
Continuation 13619064 · Sep 14, 2012
Continuation 12900717 · Oct 8, 2010
Continuation 12077016 · Mar 14, 2008
Provisional Application 60918540 · Mar 16, 2007
Related Publication 20220118285A1 · Apr 21, 2022