Configurable platform
An image sensor assembly includes at least one upconverter configured to detect light in a NIR waveband that is received from an object to be imaged and generate, based on the detected light, upconverted light that is outside of the NIR waveband; and at least one image sensor configured to detect the upconverted light.
1. An image sensor assembly for imaging tissue comprising:
at least one upconverter configured to:
detect fluorescence emission light in a near-infrared (NIR) waveband that is received from tissue to be imaged and generate, based on the detected fluorescence emission light, upconverted light that is outside of the NIR waveband, and
transmit at least a portion of visible light that is reflected from the tissue to be imaged; and
at least one image sensor configured to detect the upconverted light for generating at least one fluorescence emission image of the tissue and detect the transmitted visible light for generating at least one reflected visible light image of the tissue.
2. The image sensor assembly of claim 1 , wherein the at least one upconverter comprises at least one NIR photodetector for detecting the fluorescence emission light in the NIR waveband.
3. The image sensor assembly of claim 1 , wherein the at least one upconverter comprises at least one light-emitting diode for generating the upconverted light.
4. The image sensor assembly of claim 3 , wherein the at least one light-emitting diode comprises an organic light-emitting diode.
5. The image sensor assembly of claim 1 , wherein the upconverted light comprises visible light.
6. The image sensor assembly of claim 1 , comprising a plurality of upconverters.
7. The image sensor assembly of claim 6 , wherein the at least one image sensor comprises a single image sensor that is configured to detect upconverted light from the plurality of upconverters.
8. The image sensor assembly of claim 1 , wherein the NIR waveband comprises a NIR-II waveband.
9. The image sensor assembly of claim 1 , wherein the at least one image sensor comprises a silicon-based sensor.
10. The image sensor assembly of claim 1 , comprising a plurality of image sensors.
11. A method for imaging tissue comprising:
detecting, by an upconverter, fluorescence emission light in a near-infrared (NIR) waveband that is received from tissue to be imaged;
generating, by the upconverter based on the detected fluorescence emission light, upconverted light that is outside of the NIR waveband, and
transmitting, by the upconverter, at least a portion of visible light that is reflected from the tissue to be imaged; and
detecting the upconverted light and the transmitted visible light by at least one image sensor.
12. The method of claim 11 , wherein the fluorescence emission light in the NIR waveband is detected by a NIR photodetector.
13. The method of claim 11 , wherein the upconverted light is generated by at least one light-emitting diode.
14. The method of claim 13 , wherein the at least one light-emitting diode comprises an organic light-emitting diode.
15. The method of claim 11 , wherein the upconverted light comprises visible light.
16. The method of claim 11 , wherein the fluorescence emission light in the NIR waveband is detected by a plurality of upconverters, and the plurality of upconverters generates the upconverted light.
17. The method of claim 16 , wherein the at least one image sensor comprises a single image sensor that detects the upconverted light from the plurality of upconverters.
18. The method of claim 11 , wherein the NIR waveband comprises a NIR-II waveband.
19. The method of claim 11 , wherein the upconverted light is detected by a plurality of image sensors.
20. The method of claim 11 , wherein the at least one sensor comprises a silicon-based sensor.
21. A fluorescence imaging system comprising the image sensor assembly of claim 1 .
22. The fluorescence imaging system of claim 21 , comprising a light source configured to generate the visible light for illuminating the tissue to be imaged and fluorescence excitation light for causing the fluorescence emission light to be emitted from the tissue.