IP Library Granted Patent US 11,992,408
Granted Patent B2
US 11,992,408 · App. 17/674,036 · Granted May 28, 2024

Methods of designing high x-ray lucency lattice structures

Inventors: Christopher Laine (Malden, MA); Ian Helmar (Beverly, MA); Lucas Diehl (Beverly, MA); Jason Tinley (Fort Worth, TX); Kevin D. Chappuis (Malden, MA); John F. Sullivan (Pelham, NH)
Assignee: NANOHIVE MEDICAL LLC
A61F2/30767A61B90/39A61F2/30942A61F2/44A61F2/4455B33Y50/00A61B2090/3966A61F2002/30028A61F2002/3008A61F2002/3009A61F2002/30141A61F2002/30143A61F2002/30146A61F2002/30148A61F2002/30151A61F2002/30153A61F2002/30154A61F2002/30171A61F2002/30263A61F2002/30273A61F2002/3028A61F2002/30331A61F2/30771A61F2002/3092A61F2002/3093A61F2002/30943A61F2002/30952A61F2002/4495A61F2250/0098A61F2310/00011
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Quick Facts
Patent No.
US 11,992,408
App. No.
17/674,036
Granted
May 28, 2024
Kind
B2
Abstract

The biocompatible lattice structures disclosed herein with an increased or optimized lucency are prepared according to multiple methods of design disclosed herein. The methods allow for the design of a metallic material with sufficient strength for use in an implant and that remains radiolucent for x-ray imaging.

Claims (20)

1. A method for manufacturing a biocompatible porous structure having increased lucency along at least one X-ray viewing direction, the method comprising:

using an analysis tool, generating a bulk volume comprising a plurality of repeating geometric unit cells, the repeating geometric unit cells comprising a plurality of nodes and a plurality of struts configured such that each strut extends radially from at least one node within a volume of the biocompatible porous structure, wherein the analysis tool is configured to analyze multiple variables;

propagating the bulk volume throughout the biocompatible porous structure;

calculating a bulk volume thickness for the biocompatible porous structure along the at least one X-ray viewing direction;

using the analysis tool, iterating across a plurality of rotations of the biocompatible porous structure to identify one or more variables resulting in the bulk volume thickness that provides the biocompatible porous structure with a predetermined lucency along the at least one X-ray viewing direction; and

manufacturing the biocompatible porous structure using the one or more variables.

2. The method of claim 1 , wherein the multiple variables comprise at least one of a size of at least one repeating geometric unit cell and a thickness of at least one of the plurality of struts.

3. The method of claim 1 , further comprising calculating the bulk volume thickness based on presence of the plurality of nodes and the plurality of struts within the volume of biocompatible porous structure.

4. The method of claim 3 , further comprising manufacturing the biocompatible porous structure such that the bulk volume thickness varies across the volume of biocompatible porous structure.

5. The method of claim 4 , further comprising manufacturing a plurality of void regions in the biocompatible porous structure, the plurality of void regions comprising one or more regions within the volume of biocompatible porous structure having a reduced bulk volume thickness.

6. The method of claim 5 , further comprising manufacturing a first average baseline lucency region in the biocompatible porous structure, the first average baseline lucency region comprising a first bulk volume thickness comprising two or more nodes from the plurality of nodes and two or more struts from the plurality of struts.

7. The method of claim 6 , further comprising manufacturing a second average baseline lucency region in the biocompatible porous structure, the second average baseline lucency region comprising a second bulk volume thickness comprising at least two nodes from the plurality of nodes, at least two struts from the plurality of struts, and at least one void region from the plurality of void regions.

8. The method of claim 7 , further comprising manufacturing the second average baseline lucency region by reducing amount of overlap between the at the least two struts along the at least one X-ray viewing direction.

9. The method of claim 8 , wherein the second bulk volume thickness is smaller than the first bulk thickness volume along the at least one X-ray viewing direction.

10. The method of claim 9 , wherein the first average baseline lucency region comprises a first lucency and the second average baseline lucency region comprises a second lucency and the second lucency is greater than the first lucency by at most 35% along the at least one X-ray viewing direction.

11. The method of claim 10 , further comprising manufacturing at least one region having a uniform bulk volume thickness along the at least one X-ray viewing direction in the second average baseline lucency region.

12. The method of claim 11 , further comprising manufacturing at least one region within the biocompatible porous structure having a bulk volume thickness greater than the first bulk medium thickness.

13. The method of claim 12 , wherein the at least one region comprises a lucency less than the first lucency.

14. The method of claim 13 , wherein the biocompatible porous structure is a medical implant.

15. The method of claim 14 , wherein the biocompatible porous structure comprises at least one of radial radial dodeca-rhombus, rhombic dodecahedron, modified rhombic dodecahedron, diamond, dodecahedron, square, pentagonal, hexagonal, octagonal, sctet struts, trunic octa, diagonal struts, and rounded or reinforced versions thereof.

Assignments (3)
SECURITY INTEREST Recorded Sep 10, 2025
From: NANOHIVE MEDICAL LLC
To: EV LENDING LLC
Reel/Frame 072212/0859 →
CHANGE OF NAME Recorded Apr 23, 2024
From: HD LIFESCIENCES LLC
To: NANOHIVE MEDICAL LLC
Reel/Frame 067194/0479 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 22, 2024
From: JONES, CHRISTOPHER L.; HELMAR, IAN; DIEHL, LUCAS; TINLEY, JASON; CHAPPUIS, KEVIN; SULLIVAN, JOHN
To: HD LIFESCIENCES LLC
Reel/Frame 067176/0761 →
Continuity (6)
Continuation 15895213 · Feb 13, 2018
Provisional Application 62619260 · Jan 19, 2018
Provisional Application 62480385 · Apr 1, 2017
Provisional Application 62480383 · Apr 1, 2017
Provisional Application 62458714 · Feb 14, 2017
Related Publication 20220168108A1 · Jun 2, 2022