Granted Patent B2

US 12,415,049 · App. 17/674,198 · Granted Sep 16, 2025

Inventors: Jaron M. Acker (Madison, WI); Craig R. Tolmie (Stoughton, WI); Robin Roehl (Janesville, WI); Jeffrey Schmidt (Fitchburg, WI); Jeff Milsap (Cambridge, WI)

Assignee: Mallinckrodt Pharmaceuticals Ireland Limited

A61M16/0051A61M16/024A61M16/1005A61M16/12A61M16/122A61M16/125A61M16/201A61M16/202A61M16/204B63C11/02G01F22/02A61M2016/0027A61M2016/0039A61M16/085A61M2016/102A61M16/208A61M2202/0275A61M2205/14A61M2205/16A61M2205/17A61M2205/3331A61M2205/3334A61M2205/3368A61M2205/3379A61M2205/50A61M2205/502A61M2205/52A61M2205/60A61M2205/6018A61M2205/6072A61M2205/8206F17C2250/00

Abstract

Claims (24)

1. A therapeutic gas source comprising:

a compressed gas cylinder of therapeutic gas; and

at least one gas source identifier attached to the compressed gas cylinder, wherein the gas source identifier contains gas source identifier information comprising at least one of gas source volume, therapeutic gas identity, therapeutic gas expiration date, and therapeutic gas concentration supplied by the therapeutic gas source,

wherein the compressed gas cylinder comprises an initial gas pressure of 2000 psi to 5000 psi and a therapeutic gas concentration of 4000 ppm to 10000 ppm, and

wherein the compressed gas cylinder weighs less than 10 pounds.

2. The therapeutic gas source of claim 1 , wherein the gas source identifier is selected from the group consisting of RFID, a QR code, a bar code, or combinations thereof.

3. The therapeutic gas source of claim 1 , wherein the therapeutic gas concentration is 4880 ppm.

4. The therapeutic gas source of claim 1 , wherein the gas source volume is a wetted volume of the gas source.

5. The therapeutic gas source of claim 1 , wherein the therapeutic gas is nitric oxide.

6. The therapeutic gas source of claim 1 , wherein the therapeutic gas source further comprises a gas source valve operable to be received by a gas source coupling within at least one gas supply subsystem of a therapeutic gas delivery system.

7. The therapeutic gas source of claim 1 , wherein the at least one gas source identifier is operable to be read by a gas source identifier reader operatively associated with a therapeutic gas delivery system when the therapeutic gas source is properly received by a gas source coupling of the therapeutic gas delivery system.

8. A therapeutic gas source comprising a compressed gas cylinder comprising an initial gas pressure of 2000 psi to 5000 psi and an NO concentration of 4000 ppm to 10000 ppm, wherein the compressed gas cylinder weighs less than 15 pounds.

9. The therapeutic gas source of claim 8 , wherein the NO concentration is 4880 ppm.

10. The therapeutic gas source of claim 8 , wherein the compressed gas cylinder weighs 1.4 pounds.

11. The therapeutic gas source of claim 8 , wherein the compressed gas cylinder weighs less than 10 pounds.

12. The therapeutic gas source of claim 8 , wherein the compressed gas cylinder comprises a gas source identifier selected from the group consisting of RFID, a QR code, a bar code, or combinations thereof.

13. The therapeutic gas source of claim 12 , wherein the gas source identifier encodes data via the RFID, QR code, bar code, or combinations thereof.

14. The therapeutic gas source of claim 13 , wherein the encoded data comprises wetted volume of the gas source, identity of the therapeutic gas, expiration date, gas source volume, type of gas therapy, concentration of therapy gas to be administered, lot number, or dosage information.

15. The therapeutic gas source of claim 14 , wherein the encoded data comprises wetted volume of the gas source, identity of the therapeutic gas, or expiration date.

16. The therapeutic gas source of claim 14 , wherein the encoded data comprises gas source volume, type of gas therapy, concentration of therapy gas to be administered, or dosage information.

17. A therapeutic gas source comprising: a compressed gas cylinder of therapeutic gas operable to be detected by a therapeutic gas source detector and at least one gas source identifier containing gas source identifier information, wherein the gas source identifier is selected from the group consisting of RFID, a QR code, a bar code, or combinations thereof, and wherein the compressed gas cylinder comprises an initial gas pressure of 2000 psi to 5000 psi and a therapeutic gas concentration is about 4000 ppm to 10000 ppm, and wherein the compressed gas cylinder weighs less than 10 pounds.

18. The therapeutic gas source of claim 17 , wherein the therapeutic gas concentration is 4880 ppm.

19. A method for administering therapeutic gas to a patient comprising connecting a compressed gas cylinder to a gas delivery system, wherein the compressed gas cylinder comprises an initial gas pressure of 2000 psi to 5000 psi and an NO concentration of a 4000 ppm to 10000 ppm, wherein the compressed gas cylinder weighs less than 15 pounds; and, activating the compressed gas cylinder.

20. A method for administering therapeutic gas to a patient comprising obtaining identifying information from a gas source identifier, wherein the gas source identifier is affixed to a compressed gas cylinder with an initial gas pressure of 2000 psi to 5000 psi having an NO concentration of a 4000 ppm to 10000 ppm, and wherein the compressed gas cylinder weighs less than 15 pounds, and the compressed gas cylinder comprises a gas source valve; communicating a signal to the gas source valve to transition to an open state.

Assignments (10)

Continuity (7)

References Cited (226)