IP Library Granted Patent US 11,531,445
Granted Patent B1
US 11,531,445 · App. 17/682,761 · Granted Dec 20, 2022

Ancestry painting

Inventors: John Michael Macpherson (Santa Ana, CA); Brian Thomas Naughton (Mountain View, CA); Joanna Louise Mountain (Menlo Park, CA)
Assignee: 23andMe, Inc.
G06F3/04812G06F3/0484G16B20/40
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Quick Facts
Patent No.
US 11,531,445
App. No.
17/682,761
Granted
Dec 20, 2022
Kind
B1
Abstract

Displaying an indication of ancestral data is disclosed. An indication that a genetic interval corresponds to a reference interval that has a likelihood of having one or more ancestral origins is received. One or more graphic display parameters are determined based at least in part on the indication. An indication of the one or more ancestral origins is visually displayed using the one or more graphic display parameters.

Claims (26)

1. A system comprising one or more processors and system memory, the one or more processors being configured to:

receive an indication of one or more local-level origins of a complex system;

determine one or more graphic display parameters based at least in part on the indication; and

visually display, in an interactive graphical user interface (GUI), a graphical representation of the one or more local-level origins using the one or more graphic display parameters.

2. The system of claim 1 , wherein the one or more graphic display parameters comprise a color assigned to each of the one or more local-level origins.

3. The system of claim 1 , wherein the indication comprises an indication that a genetic interval of a genome of an individual corresponds to a reference interval that has a likelihood of having one or more ancestral origins.

4. A method for displaying ancestral origins, comprising:

receiving an indication of one or more ancestral origins of a genetic interval of a genome of an individual;

determining one or more graphic display parameters based at least in part on the indication; and

visually displaying, in an interactive graphical user interface (GUI), a graphical representation of the one or more ancestral origins of the genetic interval using the one or more graphic display parameters.

5. The method of claim 4 wherein the one or more graphic display parameters comprise a color assigned to each of the ancestral origins of the genetic interval.

6. The method of claim 4 , wherein the one or more graphic display parameters comprise a position of the genetic interval in an autosomal chromosome.

7. The method of claim 6 , wherein the graphical representation of the one or more ancestral origins of the genetic interval comprises a graphical representation of the chromosome having an interval filled with a color assigned to one of the one or more ancestral origins, the interval filled with the color being at the position of the genetic interval in the autosomal chromosome.

8. The method of claim 4 , wherein the one or more ancestral origins of the genetic interval are displayed using a density plot or a contour plot.

9. A computer program product for displaying ancestral origins, the computer program product being embodied in a computer readable medium and comprising computer instructions for:

receiving an indication of one or more ancestral origins of a genetic interval of a genome of an individual;

determining one or more graphic display parameters based at least in part on the indication; and

visually displaying, in an interactive graphical user interface (GUI), a graphical representation of the one or more ancestral origins of the genetic interval using the one or more graphic display parameters.

10. The computer program product of claim 9 , wherein the one or more graphic display parameters include a color assigned to each of the one or more ancestral origins.

11. The method of claim 4 , wherein the genetic interval comprises an autosomal chromosome segment.

12. The method of claim 4 , wherein the genetic interval comprises a pair of autosomal chromosome segments.

13. The method of claim 7 , wherein the chromosome is divided into intervals representing a plurality of genetic intervals, including the genetic interval.

14. The method of claim 13 , wherein colors are used to fill in the intervals.

15. The method of claim 4 , further comprising displaying a percentage associated with each of the one or more ancestral origins.

16. The method of claim 4 , wherein receiving the indication of the one or more ancestral origins of the genetic interval comprises looking up the genetic interval in a table of genotype frequencies associated with a plurality of ancestral origins to determine an ancestral assignment for the genetic interval.

17. The method of claim 4 , wherein receiving the indication of the one or more ancestral origins of the genetic interval comprises using a sliding window to smooth out ancestral origin assignments.

Assignments (4)
CORRECTIVE ASSIGNMENT TO CORRECT THE APP. NO. 63806415 TO 63806145 AND APPL NO. 17721779 TO 17731779 PREVIOUSLY RECORDED ON REEL 73168 FRAME 531. ASSIGNOR(S) HEREBY CONFIRMS THE CHANGE OF NAME. Recorded Jan 6, 2026
From: 23ANDME PGS LLC
To: 23ANDME GENOMICS LLC
Reel/Frame 074434/0334 →
CHANGE OF NAME Recorded Oct 22, 2025
From: 23ANDME PGS LLC
To: 23ANDME GENOMICS LLC
Reel/Frame 073168/0531 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 26, 2025
From: 23ANDME, INC.
To: 23ANDME PGS LLC
Reel/Frame 072562/0795 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 8, 2022
From: MACPHERSON, JOHN MICHAEL; NAUGHTON, BRIAN THOMAS; MOUNTAIN, JOANNA LOUISE
To: 23ANDME, INC.
Reel/Frame 061689/0620 →
Continuity (4)
Continuation 16226116 · Dec 19, 2018
Continuation 15267053 · Sep 15, 2016
Continuation 12381992 · Mar 18, 2009
Provisional Application 61070310 · Mar 19, 2008