IP Library Granted Patent US 12,497,650
Granted Patent B2
US 12,497,650 · App. 17/690,796 · Granted Dec 16, 2025

Methods for lowering the incidence of hemorrhagic heart disease in swine

Inventor: Daniela do Amaral Grossi (Saskatoon, CA)
Assignee: INGURAN, LLC
C12Q1/6827A01K67/02C12Q1/6858A01K2227/108C12Q1/6883
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Quick Facts
Patent No.
US 12,497,650
App. No.
17/690,796
Granted
Dec 16, 2025
Kind
B2
Abstract

The invention encompasses methods for reducing the incidence of hemorrhagic heart disease in livestock.

Claims (6)

1 . A method of reducing the incidence of Mulberry heart disease in a Sus scrofa population comprising:

identifying selection candidates in the population;

for each selection candidate, determining i) an allele of a single nucleotide polymorphism corresponding to position 204959669 of chromosome 13 of Sus scrofa , or ii) an allele of a genetic marker in linkage disequilibrium with the single nucleotide polymorphism wherein the allele of the genetic marker in linkage disequilibrium with the single nucleotide polymorphism is perfectly predictive of an allele of the single nucleotide polymorphism;

selecting parents from among the selection candidates based on the determined allele of the single nucleotide polymorphism or based on the determined allele of the genetic marker in linkage disequilibrium with the single nucleotide polymorphism in the population; and

producing progeny from the parents.

2 . The method of claim 1 , further comprising the step of correlating the determined allele of the single nucleotide polymorphism or the determined allele of the genetic marker with the risk of Mulberry heart disease in the individual.

Assignments (2)
SECURITY INTEREST Recorded Nov 24, 2025
From: INGURAN, LLC
To: BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 073783/0924 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 28, 2022
From: GROSSI, DANIELA DO AMARAL
To: INGURAN, LLC
Reel/Frame 059764/0679 →