Contact lens treating solution
A contact lens treating solution includes (a) about 0.005 to about 2 wt. %, based on the total weight of the contact lens treating solution, of hyaluronic acid or a salt thereof; (b) about 0.01 to about 1 wt. %, based on the total weight of the contact lens treating solution, of erythritol; (c) one or more nonionic surfactants; (d) sodium chloride, potassium chloride or any combination thereof; and (e) one or more buffers.
1 . A contact lens treating solution, consisting of:
(a) about 0.005 to about 2 wt. %, based on the total weight of the contact lens treating solution, of hyaluronic acid or a salt thereof;
(b) about 0.01 to about 1 wt. %, based on the total weight of the contact lens treating solution, of erythritol;
(c) one or more nonionic surfactants;
(d) one or more of sodium chloride and potassium chloride;
(e) one or more buffers;
(f) one or more chelating agents;
(g) one or more antimicrobial agents; and
(h) water.
2 . The contact lens treating solution of claim 1 , consisting of:
(a) about 0.01 to about 0.2 wt. %, based on the total weight of the contact lens treating solution, of hyaluronic acid or a salt thereof; and
(b) about 0.05 to about 0.5 wt. %, based on the total weight of the contact lens treating solution, of erythritol.
3 . The contact lens treating solution of claim 1 , wherein the one or more nonionic surfactants are one or more of a poloxamer and a poloxamine.
4 . The contact lens treating solution of claim 1 , consisting of:
about 0.05 to about 5 wt. %, based on the total weight of the contact lens treating solution, of the one or more nonionic surfactants;
about 0.01 to about 5 wt. %, based on the total weight of the contact lens treating solution, of the one or more of sodium chloride and potassium chloride; and
about 0.1 to about 10% (w/w) of the one or more buffers.
5 . The contact lens treating solution of claim 1 , wherein the one or more antimicrobial agents include of one or more biguanide antimicrobial agents and one or more quaternary ammonium antimicrobial agents.
6 . The contact lens treating solution of claim 5 , wherein the one or more biguanide antimicrobial agents are poly (hexamethylene biguanide) and alexidine, and the one or more quaternary ammonium antimicrobial agents are Polyquaternium-1.
7 . The contact lens treating solution of claim 5 , consisting of:
about 0.5 ppm to about 10 ppm, based on total weight of the contact lens treating solution, of the one or more biguanide antimicrobial agents; and
about 0.5 ppm to about 10 ppm, based on total weight of the contact lens treating solution, of the one or more quaternary ammonium antimicrobial agents.
8 . The contact lens treating solution of claim 1 , wherein the contact lens treating solution satisfies the biocidal requirements of a Stand-Alone Procedure for Disinfecting Products.
9 . The contact lens treating solution of claim 1 , in the form of an eye care product or a contact lens care product selected from the group consisting of a contact lens preservative solution, a contact lens cleaning solution, a contact lens rewetting solution and a contact lens multi-purpose solution.
10 . The contact lens treating solution of claim 1 , consisting of:
about 0.05 to about 5 wt. %, based on the total weight of the contact lens treating solution, of the one or more nonionic surfactants;
about 0.01 to about 5 wt. %, based on the total weight of the contact lens treating solution, of the one or more of sodium chloride and potassium chloride;
about 0.1 to about 10% (w/w) of the one or more buffers;
about 0.005% to about 0.05% (w/w) of the one or more chelating agents; and
about 0.5 ppm to about 10 ppm, based on total weight of the contact lens treating solution, of the one or more antimicrobial agents.
11 . The contact lens treating solution of claim 1 , consisting of:
about 0.01 to about 0.2 wt. %, based on the total weight of the contact lens treating solution, of hyaluronic acid or a salt thereof;
about 0.05 to about 0.5 wt. %, based on the total weight of the contact lens treating solution, of erythritol;
about 0.1 to about 2 wt. %, based on the total weight of the contact lens treating solution, of the one or more nonionic surfactants;
about 0.01 to about 5 wt. %, based on the total weight of the contact lens treating solution, of the one or more of sodium chloride and potassium chloride;
about 0.1 to about 10% (w/w) of the one or more buffers;
about 0.005% to about 0.05% (w/w) of the one or more chelating agents; and
about 0.5 ppm to about 10 ppm, based on total weight of the contact lens treating solution, of the one or more antimicrobial agents.
12 . The contact lens treating solution of claim 1 , wherein the one or more chelating agents are ethylenediaminetetraacetic acid (EDTA) or a metal salt thereof, and the one or more antimicrobial agents include poly (hexamethylene biguanide), alexidine, and Polyquaternium-1.
13 . The contact lens treating solution of claim 12 , wherein the one or more nonionic surfactants include one or more of a poloxamer and a poloxamine.
14 . The contact lens treating solution of claim 1 , having an osmolality of about 200 mOsmol/kg to about 400 mOsmol/kg.
15 . The contact lens treating solution of claim 14 , having a pH of about 6 to about 8.