IP Library › Patent Application 17696184
Patent Application
App. No. 17/696,184

Compositions and Methods for Targeting Cancer Stem Cells

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Quick Facts
Patent No.
US None
App. No.
17/696,184
Abstract

The present invention provides methods of testing anti-STn antibodies for their ability target cancer stem cells by isolating cancer stem cells from cultures, contacting them with anti-STn antibodies being tested, and measuring resulting cell viability.

Claims (6)

1 . A method of testing an anti-sialyl Tn antigen (STn) antibody for the ability to target cancer stem cells (CSCs) comprising:

(a) culturing one or more cell lines,

(b) isolating one or more sub-fractions, wherein said one or more sub-fractions express at least one CSC marker,

(c) contacting said one or more sub-fractions with said anti-STn antibody, and

(d) measuring cell viability in said one or more sub-fractions.

2 - 21 . (canceled)