IP Library Granted Patent US 12,357,739
Granted Patent B2
US 12,357,739 · App. 17/738,368 · Granted Jul 15, 2025

Automated peritoneal dialysis system having a disposable cassette and valve seat therefore

Inventors: Jack Alexander Hornsby (Tempsford, GB); Lewis Siu Tai Ho (Hertfordshire, GB); Sergio Malorni (Cambridgeshire, GB); Jonathan Paul Cooke (Cambridge, GB); Akshaya Ahuja (St Neots, GB); Emil Preda (Cambourne, GB)
Assignees: BAXTER INTERNATIONAL INC.; BAXTER HEALTHCARE SA
A61M1/281A61M1/154A61M1/155A61M1/1565A61M1/159A61M1/1601A61M1/166A61M1/282A61M1/288A61M2205/12A61M2205/128A61M2205/14A61M2205/3331A61M2205/3334A61M2205/3344A61M2205/3368A61M2205/3386A61M2205/3393A61M2205/502
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Quick Facts
Patent No.
US 12,357,739
App. No.
17/738,368
Granted
Jul 15, 2025
Kind
B2
Abstract

A peritoneal dialysis system comprises a cycler including a pump actuator, a patient line valve actuator, at least one supply line valve actuator, and a drain line valve actuator; and a disposable medical fluid cassette including a pumping portion configured to operate with the pump actuator, a patient line valve seat configured to operate with the patient line valve actuator, a rigid body defining a common well, at least one supply line valve seat located in the common well and configured to operate with at least one supply line valve actuator, and a drain line valve seat located in the common well and configured to operate with the drain line valve actuator.

Claims (35)

1. A disposable medical fluid cassette comprising:

a pumping portion;

a patient line valve seat positioned to fluidly communicate with the pumping portion;

a rigid body defining a common well, the common well in fluid communication with the pumping portion;

at least one supply line valve seat located in the common well; and

a drain line valve seat located in the common well.

2. The disposable medical fluid cassette of claim 1 , wherein the patient line valve seat is provided by the rigid body.

3. The disposable medical fluid cassette of claim 1 , wherein the pumping portion includes a peristaltic pump tube attached to the rigid body.

4. The disposable medical fluid cassette of claim 1 , wherein the pumping portion includes a pump chamber defined by the rigid body.

5. The disposable medical fluid cassette of claim 1 , wherein the rigid body defines an inline fluid heating pathway located between the patient line valve seat and the pumping portion.

6. The disposable medical fluid cassette of claim 5 , which includes a temperature sensing area located between the patient line valve seat and the inline fluid heating pathway.

7. The disposable medical fluid cassette of claim 5 , wherein the inline fluid heating pathway is configured such that fresh dialysis fluid flows upwardly during priming to remove air through the patient line valve seat.

8. The disposable medical fluid cassette of claim 5 , which includes at least one of a pumping pressure sensing pod located between the drain line valve seat and a first end of the inline fluid heating pathway or a patient pressure sensing pod located between the patient line valve seat and a second end of the inline fluid heating pathway.

9. The disposable medical fluid cassette of claim 1 , which includes at least one of a patient line in fluid communication with the patient line valve seat, at least one supply line in fluid communication with the at least one supply line valve seat, or a drain line in fluid communication with the drain line valve seat.

10. The disposable medical fluid cassette of claim 1 , which includes at least one of a pumping pressure sensing pod located adjacent to the patient line valve seat or a pumping pressure sensing pod located adjacent to the common well.

11. The disposable medical fluid cassette of claim 1 , which includes a flexible sheet sealed to the rigid body, the flexible sheet flexed to open and close the at least one supply line valve seat and the drain line valve seat.

12. The disposable medical fluid cassette of claim 11 , wherein the rigid body includes rigid walls defining the common well, the flexible sheet sealed to the rigid walls to enclose the common well.

13. The disposable medical fluid cassette of claim 1 , wherein at least one of the patient line valve seat, the at least one supply line valve seat or the drain line valve seat includes a tapered sealing surface surrounded by a plurality of displacement ribs, at least some of the displacement ribs spaced apart to mitigate against flexible sheet ingress into the tapered sealing surface.

14. The disposable medical fluid cassette of claim 1 , wherein the common well includes a ramp configured to direct air in the common well towards the drain line valve seat.

15. The disposable medical fluid cassette of claim 1 , wherein the drain line valve seat is positioned relative to the at least one supply line valve seat in the common well, such that the drain line valve seat is elevationally higher than the at least one supply line valve seat to direct air towards the drain line valve seat when the disposable medical fluid cassette is loaded for operation.

16. A peritoneal dialysis system comprising:

a cycler including

a pump actuator,

a patient line valve actuator,

at least one supply line valve actuator, and

a drain line valve actuator; and

a disposable medical fluid cassette including

a pumping portion configured to operate with the pump actuator,

a patient line valve seat configured to operate with the patient line valve actuator,

a rigid body defining a common well,

at least one supply line valve seat located in the common well and configured to operate with at least one supply line valve actuator, and

a drain line valve seat located in the common well and configured to operate with the drain line valve actuator.

17. The peritoneal dialysis system of claim 16 , wherein the cycler is configured to perform a patient drain in which used dialysis fluid enters the common well followed by a patient fill in which fresh dialysis fluid enters the common well.

18. The peritoneal dialysis system of claim 17 , wherein during the patient drain, the drain line valve actuator is actuated so that used dialysis fluid is able to exit the common well via the drain line valve seat, and wherein during the patient fill, one of the at least one supply line valve actuators is actuated so that fresh dialysis fluid is able to enter the common well via one of the at least one supply line valve seats.

19. The peritoneal dialysis system of claim 17 , wherein during the patient drain and the patient fill, the patient line valve actuator is actuated so that used and fresh dialysis fluid, respectively, is able to flow through the patient line valve seat.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 31, 2025
From: BAXTER HEALTHCARE SA
To: VANTIVE HEALTH GMBH
Reel/Frame 074046/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 31, 2025
From: BAXTER INTERNATIONAL INC.
To: VANTIVE US HEALTHCARE LLC
Reel/Frame 074046/0769 →
SECURITY INTEREST Recorded Jan 31, 2025
From: VANTIVE US HEALTHCARE LLC; GAMBRO RENAL PRODUCTS, INC.
To: ARES CAPITAL CORPORATION
Reel/Frame 070076/0701 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 16, 2022
From: HORNSBY, JACK ALEXANDER; HO, LEWIS SIU TAI; MALORNI, SERGIO; COOKE, JONATHAN PAUL; AHUJA, AKSHAYA; PREDA, EMIL
To: BAXTER INTERNATIONAL INC.; BAXTER HEALTHCARE SA
Reel/Frame 060223/0287 →
Continuity (2)
Provisional Application 63185050 · May 6, 2021
Related Publication 20220355005A1 · Nov 10, 2022
References Cited (11)
US 20070278155A1 · Lo et al. · 2007 [cited by applicant]
US 20120085707A1 · Beiriger · 2012 [cited by applicant]
US 20140207055A1 · Neftel et al. · 2014 [cited by applicant]
US 20140276375A1 · Minkus · 2014 [cited by applicant]
EP 2167160B1 · 2015 [cited by applicant]
IT BO20090649A1 · 2011 [cited by applicant]
International Preliminary Report on Patentability No. PCT/US2022/028067 dated Oct. 23, 2023. [cited by applicant]
Written Opinion PCT/US2022/028067 dated Oct. 23, 2023. [cited by applicant]
International Search Report for International Application No. PCT/US2022/028067 dated Dec. 2, 2022. [cited by applicant]
International Preliminary Report on Patentability for International Patent Application No. PCT/US2022/028059, mailed Nov. 16, 2023. 8 pages. [cited by applicant]
International Preliminary Report on Patentability No. PCT/US2022/028068 dated Mar. 23, 2023. [cited by applicant]