Granted Patent
B2
US 11,951,114 · App. 17/738,621 · Granted Apr 9, 2024
Use of thyroid beta-agonists
Inventors:
Brian Lian (San Diego, CA); Rochelle Hanley (Ann Arbor, MI); Misha Dinerman (Cincinnati, OH); Mark Erion (Brookline, MA); Serge Boyer (San Diego, CA); Hongjian Jiang (Shanghai, CN)
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Abstract
Methods useful for treating X-linked adrenoleukodystrophy are provided.
Claims (9)
1. A method for treating X-linked adrenoleukodystrophy, comprising administering to a subject a compound selected from:
or a salt or ester thereof.
2. The method of claim 1 , wherein the compound is
or a salt or ester thereof.
3. The method of claim 2 , wherein the compound is
4. The method of claim 1 , wherein the compound is
or a salt or ester thereof.
5. The method of claim 4 , wherein the compound is
6. The method of claim 1 , wherein the compound is administered daily, every other day, or intermittently for three months followed by a period of time of one month when the compound is not administered.
Assignments (4)
SECURITY INTEREST
Recorded Oct 18, 2023
From: CYDEX PHARMACEUTICALS, INC.; LIGAND PHARMACEUTICALS INCORPORATED; METABASIS THERAPEUTICS, INC.; PFENEX INC.
To: CITIBANK, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 065271/0025 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Nov 21, 2022
From: LIAN, BRIAN; HANLEY, ROCHELLE; DINERMAN, MISHA
To: VIKING THERAPEUTICS, INC.
Reel/Frame 061841/0372 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Nov 21, 2022
From: ERION, MARK; BOYER, SERGE
To: METABASIS THERAPEUTICS, INC.
Reel/Frame 061841/0484 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Nov 21, 2022
From: JIANG, HONGJIAN
To: METABASIS THERAPEUTICS, INC.
Reel/Frame 061841/0568 →