(+)-TRANS TETRAHYDROCANNABINOL ((+)-TRANS-THC) FOR USE AS A MEDICAMENT
The present invention relates to a tetrahydrocannabinol (THC) type cannabinoid compound for use as a medicament. The THC-type cannabinoid is an enantiomer of the (−)-trans-tetrahydrocannabinol which is a naturally occurring cannabinoid that can be found in cannabis plant strains which have been bred to yield THC as the dominant cannabinoid. The particular enantiomer (+)-trans tetrahydrocannabinol has been found to have properties which are different from the naturally occurring (−)-trans-THC. The cannabinoid (+)-trans-THC has been found to occur in low concentrations in particular cannabis plant strains. Furthermore, the cannabinoid can be produced by synthetic means.
1 . (+)-trans tetrahydrocannabinol ((+)-trans-THC) for use as a medicament.
2 . (+)-trans-THC for use according to claim 1 , wherein the (+)-trans-THC is in the form of a plant extract.
3 . (+)-trans-THC for use according to claim 2 , wherein the (+)-trans-THC is in the form of a highly purified plant extract.
4 . (+)-trans-THC for use according to claim 3 , wherein the (+)-trans-THC comprises at least 80% (w/w) (+)-trans-THC.
5 . (+)-trans-THC for use according to claim 3 , wherein the (+)-trans-THC comprises at least 95% (w/w) (+)-trans-THC.
6 . (+)-trans-THC for use according to claim 1 , wherein the (+)-trans-THC is in the form of a synthetic compound.
7 . (+)-trans-THC for use according to any of the preceding claims, wherein the dose of (+)-trans-THC is greater than 100 mg/kg/day.
8 . (+)-trans-THC for use according to any of the preceding claims, wherein the dose of (+)-trans-THC is less than 100 mg/kg/day.
9 . A composition for use as a medicament comprising (+)-trans-tetrahydrocannabinol ((+)-trans-THC) and one or more pharmaceutically acceptable excipients.
10 . (+)-trans tetrahydrocannabinol ((+)-trans-THC) for use in the treatment of pain.
11 . A process for the preparation of (+)-trans tetrahydrocannabinol ((+)-trans-THC).