Patent Application
Utility
PCT National Stage
App. No. 17/774,477
· Confirmation No. 8235
EXTRAHEPATIC DELIVERY
Inventors:
Jayaprakash K. NAIR, Martin A. MAIER, Juan C. SALINAS, Shigeo MATSUDA, Alexander V. KEL'IN, Scott P. LENTINI, Guo HE, Michelle H. JUNG, Justin M. PIERSON, Muthiah MANOHARAN, Dale C. GUENTHER, Ivan ZLATEV, Christopher S. THEILE, Vasant R. JADHAV, Stuart MILSTEIN, Maja JANAS, Dhrubajyoti DATTA
Applicant:
ALNYLAM PHARMACEUTICALS, INC.
Docketed New Case - Ready for Examination
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Code | Description | Pages | ||
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| 2026-04-28 | IDS |
Information Disclosure Statement (IDS) Form (SB08) | 6 | View | |
| 2026-04-28 | N417 |
Electronic Filing System Acknowledgment Receipt | 3 | View | |
| 2026-04-28 | A.NE |
Response After Final Action | — | View | |
| 2026-04-28 | RCEX |
Request for Continued Examination (RCE) | 3 | View | |
| 2026-04-28 | AMSB |
Amendment Submitted/Entered with Filing of Continued Prosecution Application (CPA)/Request for Continued Examination(RCE) | 1 | View | |
| 2026-04-28 | CLM |
Claims | 6 | View | |
| 2026-04-28 | REM |
Applicant Arguments/Remarks Made in an Amendment | 9 | View | |
| 2026-04-28 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2026-04-28 | N417.PYMT |
Electronic Fee Payment | 2 | View | |
| 2026-04-28 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2025-12-31 | CTFR |
Final Rejection | 22 | View | |
| 2025-12-31 | SRFW |
Search information including classification, databases and other search related notes | 2 | View | |
| 2025-12-31 | SRNT |
Examiner's search strategy and results | 14 | View | |
| 2025-12-31 | SRNT |
Examiner's search strategy and results | 7 | View | |
| 2025-10-23 | CRFE |
Sequence Listing in Computer Readable Format, No errors found | — | View | |
| 2025-10-23 | A... |
Amendment/Request for Reconsideration-After Non-Final Rejection | — | View | |
| 2025-10-23 | A... |
Amendment/Request for Reconsideration-After Non-Final Rejection | 1 | View | |
| 2025-10-23 | SPEC |
Specification | 1 | View | |
| 2025-10-23 | CLM |
Claims | 8 | View | |
| 2025-10-23 | DRW |
Drawings-only black and white line drawings | 1 | View | |
| 2025-10-23 | REM |
Applicant Arguments/Remarks Made in an Amendment | 9 | View | |
| 2025-10-23 | DRW |
Drawings-only black and white line drawings | 13 | View | |
| 2025-10-23 | SPEC |
Specification | 273 | View | |
| 2025-10-23 | SPEC |
Specification | 273 | View | |
| 2025-10-23 | SEQLIST |
Sequence Listing | 57 | View | |
| 2025-10-23 | N417.PYMT |
Electronic Fee Payment | 2 | View | |
| 2025-10-23 | N417 |
Electronic Filing System Acknowledgment Receipt | 3 | View | |
| 2025-10-23 | DRW.SUPP |
Drawings-black and white line and/or other drawings | — | View | |
| 2025-10-23 | DRW.SUPP |
Drawings-black and white line and/or other drawings | — | View | |
| 2025-10-23 | SCORE |
Placeholder sheet indicating presence of supplemental content in Supplemental Complex Repository for Examiners(SCORE) | 1 | View | |
| 2025-10-23 | SEQ.TXT |
Sequence Listing (Text File) | 1 | View | |
| 2025-10-23 | CRFE |
Sequence Listing in Computer Readable Format, No errors found | 28 | View | |
| 2025-07-25 | CTNF |
Non-Final Rejection | 29 | View | |
| 2025-07-25 | 892 |
List of references cited by examiner | 1 | View | |
| 2025-07-25 | SRFW |
Search information including classification, databases and other search related notes | 2 | View | |
| 2025-07-25 | SRNT |
Examiner's search strategy and results | 2 | View | |
| 2025-07-25 | BIB |
Bibliographic Data Sheet | 2 | View | |
| 2025-07-25 | SRNT |
Examiner's search strategy and results | 12 | View | |
| 2025-07-25 | SRNT |
Examiner's search strategy and results | 23 | View | |
| 2025-07-25 | 1449 |
List of References cited by applicant and considered by examiner | 5 | View | |
| 2025-07-25 | 1449 |
List of References cited by applicant and considered by examiner | 5 | View | |
| 2025-07-25 | 1449 |
List of References cited by applicant and considered by examiner | 4 | View | |
| 2025-07-25 | 1449 |
List of References cited by applicant and considered by examiner | 5 | View | |
| 2025-07-25 | 1449 |
List of References cited by applicant and considered by examiner | 4 | View | |
| 2025-05-28 | ELC. |
Response to Election / Restriction Filed | — | View | |
| 2025-05-28 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2025-05-28 | ELC. |
Response to Election / Restriction Filed | 1 | View | |
| 2025-05-28 | CLM |
Claims | 9 | View | |
| 2025-05-28 | REM |
Applicant Arguments/Remarks Made in an Amendment | 2 | View | |
| 2025-05-28 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2025-04-11 | CTRS |
Requirement for Restriction/Election | 7 | View | |
| 2025-02-07 | IDS |
Information Disclosure Statement (IDS) Form (SB08) | 5 | View | |
| 2025-02-07 | TRAN.LET |
Transmittal Letter | 2 | View | |
| 2025-02-07 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2024-07-26 | FOR |
Foreign Reference | 124 | View | |
| 2024-07-26 | IDS |
Information Disclosure Statement (IDS) Form (SB08) | 4 | View | |
| 2024-07-26 | FOR |
Foreign Reference | 150 | View | |
| 2024-07-26 | FOR |
Foreign Reference | 234 | View | |
| 2024-07-26 | FOR |
Foreign Reference | 127 | View | |
| 2024-07-26 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2024-02-21 | FOR |
Foreign Reference | 263 | View | |
| 2024-02-21 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2024-02-21 | IDS |
Information Disclosure Statement (IDS) Form (SB08) | 4 | View | |
| 2024-02-21 | FOR |
Foreign Reference | 442 | View | |
| 2023-08-15 | IDS |
Information Disclosure Statement (IDS) Form (SB08) | 5 | View | |
| 2023-08-15 | FOR |
Foreign Reference | 114 | View | |
| 2023-08-15 | FOR |
Foreign Reference | 28 | View | |
| 2023-08-15 | FOR |
Foreign Reference | 1 | View | |
| 2023-08-15 | FOR |
Foreign Reference | 102 | View | |
| 2023-08-15 | FOR |
Foreign Reference | 30 | View | |
| 2023-08-15 | FOR |
Foreign Reference | 203 | View | |
| 2023-08-15 | FOR |
Foreign Reference | 76 | View | |
| 2023-08-15 | FOR |
Foreign Reference | 41 | View | |
| 2023-08-15 | FOR |
Foreign Reference | 114 | View | |
| 2023-08-15 | N417 |
Electronic Filing System Acknowledgment Receipt | 4 | View | |
| 2023-08-15 | FOR |
Foreign Reference | 310 | View | |
| 2023-01-19 | NTC.PUB |
Notice of Publication | 1 | View | |
| 2023-01-10 | OATH |
Oath or Declaration filed | 17 | View | |
| 2023-01-10 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2022-12-06 | A.PE |
Preliminary Amendment | 1 | View | |
| 2022-12-06 | SPEC |
Specification | 7 | View | |
| 2022-12-06 | CLM |
Claims | 8 | View | |
| 2022-12-06 | REM |
Applicant Arguments/Remarks Made in an Amendment | 1 | View | |
| 2022-12-06 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2022-12-06 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2022-08-31 | WCLM |
Claims Worksheet (PTO-2022) | 1 | View | |
| 2022-08-31 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2022-08-31 | M903 |
Notice of Designated Office (DO) / Elected Office (EO) Acceptance Mailed | 2 | View | |
| 2022-08-31 | APP.FILE.REC |
Filing Receipt | 4 | View | |
| 2022-05-04 | PA.. |
Power of Attorney | 2 | View | |
| 2022-05-04 | A.PE |
Preliminary Amendment | 1 | View | |
| 2022-05-04 | SPEC |
Specification | 1 | View | |
| 2022-05-04 | CLM |
Claims | 9 | View | |
| 2022-05-04 | REM |
Applicant Arguments/Remarks Made in an Amendment | 1 | View | |
| 2022-05-04 | 371P |
Documents submitted with 371 (National Stage) Applications | 8 | View | |
| 2022-05-04 | DRW.NONBW |
Drawings-other than black and white line drawings | 13 | View | |
| 2022-05-04 | 371P |
Documents submitted with 371 (National Stage) Applications | 297 | View | |
| 2022-05-04 | IDS |
Information Disclosure Statement (IDS) Form (SB08) | 5 | View | |
| 2022-05-04 | TRNA |
Transmittal of New Application | 4 | View | |
| 2022-05-04 | FOR |
Foreign Reference | 30 | View | |
| 2022-05-04 | FOR |
Foreign Reference | 64 | View | |
| 2022-05-04 | FOR |
Foreign Reference | 263 | View | |
| 2022-05-04 | FOR |
Foreign Reference | 163 | View | |
| 2022-05-04 | FOR |
Foreign Reference | 69 | View | |
| 2022-05-04 | FOR |
Foreign Reference | 347 | View | |
| 2022-05-04 | WFEE |
Fee Worksheet (SB06) | 2 | View | |
| 2022-05-04 | N417 |
Electronic Filing System Acknowledgment Receipt | 5 | View | |
| 2022-05-04 | ADS |
Application Data Sheet | 13 | View | |
| 2022-05-04 | SPEC |
Specification | 270 | View | |
| 2022-05-04 | ABST |
Abstract | 1 | View | |
| 2022-05-04 | FRPR |
Certified Copy of Foreign Priority Application | 258 | View | |
| 2022-05-04 | DRW |
Drawings-only black and white line drawings | 13 | View | |
| 2022-05-04 | CLM |
Claims | 13 | View | |
| 2022-05-04 | ABST |
Abstract | 1 | View | |
| 2022-05-04 | P.N.101.CONV |
PCT/RO/101 - Request form for new International Application - Conventional | 7 | View | |
| 2022-05-04 | SCORE |
Placeholder sheet indicating presence of supplemental content in Supplemental Complex Repository for Examiners(SCORE) | 1 | View | |
| 2022-05-04 | DRW.SUPP |
Drawings-black and white line and/or other drawings | — | View |
Inventors
Jayaprakash K. NAIR
Cambridge, MA
Martin A. MAIER
Cambridge, MA
Juan C. SALINAS
Cambridge, MA
Shigeo MATSUDA
Cambridge, MA
Alexander V. KEL'IN
Cambridge, MA
Scott P. LENTINI
Cambridge, MA
Guo HE
Cambridge, MA
Michelle H. JUNG
Cambridge, MA
Justin M. PIERSON
Cambridge, MA
Muthiah MANOHARAN
Cambridge, MA
Dale C. GUENTHER
Cambridge, MA
Ivan ZLATEV
Cambridge, MA
Christopher S. THEILE
Cambridge, MA
Vasant R. JADHAV
Cambridge, MA
Stuart MILSTEIN
Cambridge, MA
Maja JANAS
Cambridge, MA
Dhrubajyoti DATTA
Cambridge, MA
Attorneys & Agents of Record
Classification
USPC
514/44A
A61K31/713
C12N15/113
A61P25/28
A61K48/0075
C12N2310/314
C12N2310/321
C12N2310/322
C12N2310/3515
C12N2310/3535
C12N2320/30
Prosecution
- Examiner
- VANHORN, ABIGAIL LOUISE
- Art Unit
- 1636
- Customer No.
- 84717
- Docket No.
- 29520.1503-US/529123
- Confirmation No.
- 8235
Publication
- Pub. No.
- US20230016929A1
- Pub. Date
- 2023-01-19
SECURITY INTEREST
Recorded 2025-10-01
from
JADHAV, VASANT R.,
MANOHARAN, MUTHIAH,
MATSUDA, SHIGEO,
GUENTHER, DALE C.,
KEL'IN, ALEXANDER V.,
JANAS, MAJA,
JUNG, MICHELLE H.,
MAIER, MARTIN A.,
PIERSON, JUSTIN M.,
DATTA, DHRUBAJYOTI,
LENTINI, SCOTT P.,
SALINAS, JUAN C.,
MILSTEIN, STUART,
THEILE, CHRISTOPHER S.,
ZLATEV, IVAN,
NAIR, JAYAPRAKASH K.,
HE, GUO
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded 2023-01-09
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Quick Facts
- App. No.
- 17/774,477
- Filed
- 2022-05-04
- Pub. No.
- US20230016929A1
- Examiner
- VANHORN, ABIGAIL LOUISE
- Art Unit
- 1636
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