Testosterone containing pharmaceutical composition
We disclose a pharmaceutical composition adapted for oral delivery comprising native testosterone; a treatment regimen comprising administration of the composition(s); and methods and uses for the treatment of hormone related conditions such as hypogonadism in human male, female and transgender subjects.
1 . A pharmaceutical composition adapted for oral administration comprising at least 10-% w/w native testosterone, at least 36% w/w sesame oil, at least 28% w/w propylene glycol monolaurate, at least 9-% w/w ethanol and at least 14-% w/w benzyl alcohol.
2 . The pharmaceutical composition according to claim 1 wherein the composition comprises or consists essentially of:
(a) about 10-% w/w native testosterone;
at least 36% w/w sesame oil;
at least 28% w/w propylene glycol monolaurate;
at least 9-% w/w ethanol; and
at least 16-% w/w benzyl alcohol, or
(b) about 10% w/w native testosterone;
at least 36% w/w sesame oil;
at least 28% w/w propylene glycol monolaurate;
at least 11% w/w ethanol; and
at least 14% w/w benzyl alcohol.