IP Library Patent Application 17799172
Patent Application
App. No. 17/799,172

COMPUTERIZED PREDICTION OF HUMERAL PROSTHESIS FOR SHOULDER SURGERY

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Patent No.
US None
App. No.
17/799,172
Abstract

A surgical assistance system obtains patient-specific values of a plurality of physical characteristics of a humeral bone of a patient. The surgical assistance system predicts, based on the patient-specific values, a humeral prosthesis ( 202 ) for the patient from among a plurality of humeral prostheses, wherein the predicted humeral prosthesis has a filling ratio less than a remodeling threshold for the patient. The filling ratio of the humeral prosthesis is a ratio of (i) a radial distance from a lengthwise central axis of a stem ( 206 ) of the humeral prosthesis to an outer surface of the stem, to (ii) a radial distance from the lengthwise central axis of the stem to an inner surface of the intramedullary canal ( 208 ) of a humerus of the patient. The remodeling threshold for the patient is a filling ratio above which the humeral prosthesis would cause remodeling in the patient.

Claims (55)

1 . A method comprising:

obtaining, by a surgical assistance system, patient-specific values of a plurality of physical characteristics of a humeral bone of a patient; and

predicting, by the surgical assistance system, based on the patient-specific values, a humeral prosthesis for the patient from among a plurality of humeral prostheses, wherein the predicted humeral prosthesis has a filling ratio less than a remodeling threshold for the patient, wherein:

the filling ratio of the humeral prosthesis is a ratio of: (i) a radial distance from a lengthwise central axis of a stem of the humeral prosthesis to an outer surface of the stem, to (ii) a radial distance from the lengthwise central axis of the stem to an inner surface of an intramedullary canal of a humerus of the patient, and

the remodeling threshold for the patient is a filling ratio above which the predicted humeral prosthesis would cause bone remodeling in the patient.

2 . The method of claim 1 , wherein:

the method comprises storing a plurality of machine-learned coefficients, and

predicting the humeral prosthesis comprises determining a humeral prosthesis index of the predicted humeral implant as a sum of a plurality of elements and a machine-learned constant, each respective element of the plurality of elements being a multiplication product of a respective machine-learned coefficient in the plurality of machine-learned coefficients and a corresponding physical characteristic in the plurality of physical characteristics of the humeral bone of the patient.

3 . The method of claim 2 , wherein the machine-learned coefficients are machine learned using a regression from humeral prosthesis indexes of humeral prostheses implanted in patients with filling ratios of the humeral prostheses that are less than remodeling thresholds for the patients.

4 . The method of claim 1 , wherein:

a region at a diaphysis of the humeral bone is partitioned into a first set of blocks, a region at a metaphysis of the humeral bone is partitioned into a second set of blocks, obtaining the patient-specific values for the plurality of physical characteristics comprises:

calculating a first value as an average of Hounsfield units of the first set of blocks that exceed a first threshold,

calculating a second value as an average of Hounsfield units of the second set of blocks that exceed a second threshold, and

calculating a third value as an average of Hounsfield units of the first set of blocks that exceed a third threshold different from the first threshold.

5 . The method of claim 4 , wherein the plurality of physical characteristics consists of the first value, the second value, and the third value.

6 . The method of claim 1 , wherein predicting the humeral prosthesis comprises predicting, by the surgical assistance system, the humeral prosthesis based on the patient-specific values of the plurality of physical characteristics of the humeral bone and based on an age of the patient.

7 . The method of claim 1 , wherein the patient-specific values regarding the physical characteristics of the humeral bone of the patient include one or more shape parameters based on changes to shape parameters of a mean statistical shape model (SSM) of a generic humeral bone to conform the mean SSM to the humeral bone of the patient

8 . A method comprising:

obtaining, by a surgical assistance system, patient-specific values of a plurality of patient-specific values, wherein:

the plurality of patient-specific values includes patient-specific values of a plurality of physical characteristics of a humeral bone of a patient, and

the plurality of physical characteristics includes (i) an average cortical metaphyseal bone density in Hounsfield units that exceed a first threshold, (ii) an average cortical spongious bone density in Hounsfield units that are less than or equal to a second threshold, and (iii) one or more shape parameters of a statistical shape model (SSM) of the humeral bone of the patient; and

predicting, by the surgical assistance system, based on the patient-specific values, a humeral prosthesis for the patient from among a plurality of humeral prostheses.

9 . The method of claim 8 , wherein the patient-specific values further include one or more of an age of the patient, a gender of the patient, or a diagnosis of the patient.

10 . The method of claim 8 , wherein:

the method comprises storing a plurality of machine-learned coefficients, and

predicting the humeral prosthesis comprises determining a humeral prosthesis index of the predicted humeral implant as a sum of a plurality of elements and a machine-learned constant, each respective element of the plurality of elements being a multiplication product of a respective machine-learned coefficient in the plurality of machine-learned coefficients and a corresponding physical characteristic in the plurality of physical characteristics of the humeral bone of the patient.

11 . A computing system comprising:

a memory configured to store medical imaging data; and

processing circuitry configured to:

obtain patient-specific values of a plurality of physical characteristics of a humeral bone of a patient and

predict, based on the patient-specific values, a humeral prosthesis for the patient from among a plurality of humeral prostheses, wherein the predicted humeral prosthesis has a filling ratio less than a remodeling threshold for the patient, wherein:

the filling ratio of the humeral prosthesis is a ratio of: (i) a radial distance from a lengthwise central axis of a stem of the humeral prosthesis to an outer surface of the stem, to (ii) a radial distance from the lengthwise central axis of the stem to an inner surface of an intramedullary canal of a humerus of the patient, and

the remodeling threshold for the patient is a filling ratio above which the predicted humeral prosthesis would cause bone remodeling in the patient.

12 . (canceled)

13 . A non-transitory computer-readable data storage medium having instructions stored thereon that, when executed, cause a computing system to:

obtain patient-specific values of a plurality of physical characteristics of a humeral bone of a patient and

predict, based on the patient-specific values, a humeral prosthesis for the patient from among a plurality of humeral prostheses, wherein the predicted humeral prosthesis has a filling ratio less than a remodeling threshold for the patient, wherein:

the filling ratio of the humeral prosthesis is a ratio of: (i) a radial distance from a lengthwise central axis of a stem of the humeral prosthesis to an outer surface of the stem, to (ii) a radial distance from the lengthwise central axis of the stem to an inner surface of an intramedullary canal of a humerus of the patient, and

the remodeling threshold for the patient is a filling ratio above which the predicted humeral prosthesis would cause bone remodeling in the patient.

14 . The computing system of claim 11 ,

wherein the memory stores a plurality of machine-learned coefficients, and

the processing circuitry is configured to, as part of predicting the humeral prosthesis, determine a humeral prosthesis index of the predicted humeral implant as a sum of a plurality of elements and a machine-learned constant, each respective element of the plurality of elements being a multiplication product of a respective machine-learned coefficient in the plurality of machine-learned coefficients and a corresponding physical characteristic in the plurality of physical characteristics of the humeral bone of the patient.

15 . The computing system of claim 14 , wherein the machine-learned coefficients are machine learned using a regression from humeral prosthesis indexes of humeral prostheses implanted in patients with filling ratios of the humeral prostheses that are less than remodeling thresholds for the patients.

16 . The computing system of claim 11 , wherein:

a region at a diaphysis of the humeral bone is partitioned into a first set of blocks,

a region at a metaphysis of the humeral bone is partitioned into a second set of blocks,

the processing circuitry is configured to, as part of obtaining the patient-specific values for the plurality of physical characteristics:

calculate a first value as an average of Hounsfield units of the first set of blocks that exceed a first threshold,

calculate a second value as an average of Hounsfield units of the second set of blocks that exceed a second threshold, and

calculate a third value as an average of Hounsfield units of the first set of blocks that exceed a third threshold different from the first threshold.

17 . The computing system of claim 16 , wherein the plurality of physical characteristics consists of the first value, the second value, and the third value.

18 . The computing system of claim 11 , wherein predicting the humeral prosthesis comprises predicting, by the surgical assistance system, the humeral prosthesis based on the patient-specific values of the plurality of physical characteristics of the humeral bone and based on an age of the patient.

19 . The computing system of claim 11 , wherein the patient-specific values regarding the physical characteristics of the humeral bone of the patient include one or more shape parameters based on changes to shape parameters of a mean statistical shape model (SSM) of a generic humeral bone to conform the mean SSM to the humeral bone of the patient.

20 . The non-transitory computer-readable data storage medium of claim 13 , wherein the instructions that cause the computing system to predict the humeral prosthesis comprises instructions that, when executed, cause the computing system to determine a humeral prosthesis index of the predicted humeral implant as a sum of a plurality of elements and a machine-learned constant, each respective element of the plurality of elements being a multiplication product of a respective machine-learned coefficient in a plurality of machine-learned coefficients and a corresponding physical characteristic in the plurality of physical characteristics of the humeral bone of the patient.

21 . The non-transitory computer-readable data storage medium of claim 20 , wherein the machine-learned coefficients are machine learned using a regression from humeral prosthesis indexes of humeral prostheses implanted in patients with filling ratios of the humeral prostheses that are less than remodeling thresholds for the patients.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 11, 2022
From: CHAOUI, JEAN; URVOY, MANUEL JEAN-MARIE
To: IMASCAP SAS
Reel/Frame 060787/0731 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 11, 2022
From: IMASCAP SAS
To: TORNIER, INC.
Reel/Frame 060787/0791 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 11, 2022
From: TORNIER, INC.
To: HOWMEDICA OSTEONICS CORP.
Reel/Frame 061149/0051 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 11, 2022
From: WALCH, GILLES
To: IMASCAP SAS
Reel/Frame 061149/0352 →