Managing fluid levels in a patient and associated devices, systems, and methods
Devices, systems, and methods for delivering fluid therapy to a patient are disclosed herein. An exemplary method can comprise obtaining a urine output rate from a patient; causing a diuretic to be provided to the patient at a dosage rate, wherein the dosage rate is increased over a period of time such that the urine output rate increases to be above a predetermined threshold within the period of time; and causing a hydration fluid to be provided to the patient at a hydration rate. The hydration rate can be set based on the urine output rate to drive net fluid loss from the patient.
1. A fluid therapy system, comprising:
a urine measurement device configured to measure urine output from a patient;
a pump configured to provide a diuretic to the patient;
one or more processors; and
tangible, non-transitory computer-readable media having instructions that, when executed by the one or more processors, cause the fluid therapy system to perform operations comprising—
obtaining a urine output rate from the urine measurement device;
causing the diuretic to be provided, via the pump, to the patient at an initial dosage rate;
increasing the dosage rate of the diuretic from the initial dosage rate to one or more additional dosage rates higher than the initial dosage rate;
after increasing the dosage rate, receiving an indication that (i) the urine output rate is above a predetermined threshold and/or (ii) a predetermined time period since causing the diuretic to be provided has elapsed; and
after receiving the indication, reducing the dosage rate of the diuretic to a reduced dosage rate that considers multiplying a value of a total amount of the diuretic delivered by a nonzero percentage.
2. The fluid therapy system of claim 1 , wherein the nonzero percentage is within a range of 10-30%.
3. The fluid therapy system of claim 1 , wherein receiving the indication comprises receiving the indication that the urine output rate is above the predetermined threshold, and wherein the predetermined threshold is at least 300 milliliters/hour.
4. The fluid therapy system of claim 1 , further comprising, after reducing the dosage rate of the diuretic, adjusting the dosage rate based at least in part on the urine output rate increasing at a rate above a predetermined rate of increase.
5. The fluid therapy system of claim 1 , wherein automatically increasing the dosage rate of the diuretic comprises automatically increasing the dosage rate over a period of time of no more than 120 minutes.
6. The fluid therapy system of claim 1 , wherein, in operation, increasing the dosage rate occurs as the urine output rate increases.
7. The fluid therapy system of claim 1 , wherein the pump is a first pump, the fluid therapy system further comprising a second pump configured to be operably coupled to a hydration fluid and provide the hydration fluid to the patient, the operations further comprising causing the hydration fluid to be provided, via the second pump, to the patient at a hydration rate no more than the urine output rate.
8. The fluid therapy system of claim 1 , wherein the reduced dosage rate considers multiplying the value of the total amount of diuretic delivered when the indication is received.
9. A fluid therapy system, comprising:
a urine measurement device configured to measure urine output from a patient;
a pump configured to provide a diuretic to the patient;
one or more processors; and
tangible, non-transitory computer-readable media having instructions that, when executed by the one or more processors, cause the fluid therapy system to perform operations comprising—
obtaining a urine output rate from the urine measurement device;
causing the diuretic to be provided, via the pump, to the patient at a dosage rate;
after causing the diuretic to be provided, receiving an indication that (i) the urine output rate is above a predetermined threshold and/or (ii) a predetermined time period since causing the diuretic to be provided has elapsed; and
after receiving the indication, reducing the dosage rate of the diuretic, wherein the reduced dosage rate is obtained via an algorithm utilizing a nonzero percentage of a total amount of the diuretic delivered.
10. A fluid therapy system, comprising:
one or more processors; and
tangible, non-transitory computer-readable media having instructions that, when executed by the one or more processors, cause the fluid therapy system to perform operations comprising—
obtaining, from a urine measurement device, a urine output rate;
causing, by a pump, the diuretic to be provided at an initial dosage rate;
increasing the dosage rate of the diuretic from the initial dosage rate to one or more additional dosage rates higher than the initial dosage rate;
after increasing the dosage rate, receiving an indication that (i) the urine output rate is above a predetermined threshold and/or (ii) a predetermined time period since causing the diuretic to be provided has elapsed; and
after receiving the indication, reducing the dosage rate of the diuretic to a reduced dosage rate that considers multiplying a value of a total amount of the diuretic delivered by a nonzero percentage.