Apparatus and method for neurovascular endoluminal intervention
An apparatus for neurovascular endoluminal intervention, in particular for the treatment of ischemic stroke, is provided. The apparatus comprises a catheter ( 2 ) for insertion into the circulatory system (CS) of a patient, in order to aspirate one or several clots (C) present in the circulatory system (CS). A distal outer section ( 22 ) of the catheter ( 2 ) comprises an unexpanded state, in which the diameter (D 2 ) of the distal outer section ( 22 ) is smaller than the diameter (D 1 ) of a proximal outer section ( 21 ) of the catheter ( 2 ), in order to facilitate navigation of the catheter through the circulatory system, and a radially expanded state, in order to facilitate aspiration of the one or several clots (C) through the catheter ( 2 ). Furthermore, a method for applying such an apparatus is provided.
1. A catheter system for neurovascular endoluminal intervention to remove one or more clots in a patient's neurovasculature, the catheter system comprising:
an elongated shaft comprising a proximal outer section with a first diameter and a distal outer section with a second diameter, the distal outer section configured to transition from an unexpanded state, wherein the second diameter is smaller than the first diameter and the second diameter is selected to permit navigation of the distal outer section through the patient's circulatory system to one or more clots in the patient's neurovasculature, to a radially expanded state to permit removal of the one or more clots through the catheter system;
a spring element coupled to a distal end of the distal outer section; and
an actuation element configured to extend through the proximal outer section and the distal outer section, the actuation element configured to be coupled to the distal end of the distal outer section via the spring element and configured to extend the distal outer section to stretch the distal outer section longitudinally and contract radially to the unexpanded state.
2. The catheter system of claim 1 , wherein the distal outer section comprises a braided structure configured to transition from the unexpanded state to the radially expanded state upon actuation of the actuation element.
3. The catheter system of claim 1 , wherein the actuation element comprises a second elongated shaft configured to push the distal end of the distal outer section distally to cause the distal outer section to extend.
4. The catheter system of claim 1 , further comprising an inner elongated shaft configured to be disposed within the elongated shaft, the inner elongated shaft longitudinally movable relative to the distal outer section of the elongated shaft.
5. The catheter system of claim 1 , wherein the spring element comprises a clip.
6. The catheter system of claim 1 , wherein the spring element comprises a semi-cylindrical structure.
7. The catheter system of claim 1 , wherein the elongated shaft is coated with PTFE.
8. The catheter system of claim 1 , wherein the actuation element is configured to be removed from the elongated shaft after expanding the distal outer section.
9. The catheter system of claim 1 , wherein the actuation element comprises a push tube.
10. The catheter system of claim 1 , wherein the actuation element comprises a widened end for coupling to the distal end of the distal outer section.
11. The catheter system of claim 1 , further comprising a coating on the distal outer section.
12. The catheter system of claim 1 , wherein the catheter system is configured to remove the one or more clots to treat ischemic stroke.
13. The catheter system of claim 1 , further comprising a clot-retriever configured to be advanced through the elongated shaft to engage with the one or more clots and to be retracted into the expanded distal outer section.
14. The catheter system of claim 1 , wherein in the radially expanded state, the second diameter of the distal outer section is the same or less than the first diameter of the proximal outer section.
15. A method for neurovascular endoluminal intervention to remove one or more clots in a patient's neurovasculature, the method comprising:
advancing a distal outer section of an elongated shaft in an unexpanded state through the patient's circulatory system to one or more clots in the patient's neurovasculature, the elongated shaft comprising a proximal outer section with a first diameter and the distal outer section with a second diameter, wherein a spring element is coupled to a distal end of the distal outer section, and wherein an actuation element extends through the proximal outer section and the distal outer section during the advancing, the actuation element coupled to the distal end of the distal outer section via the spring element to extend the distal outer section to stretch longitudinally and contract radially to the unexpanded state;
causing, via the actuation element, the distal outer section to transition from the unexpanded state to a radially expanded state; and
removing the one or more clots through the elongated shaft while the distal outer section is in the radially expanded state.
16. The method of claim 15 , wherein removing the one or more clots comprises aspirating the one or more clots while the distal outer section is in the radially expanded state.
17. The method of claim 15 , further comprising, after causing the distal outer section to transition to the radially expanded state, removing the actuation element from the elongated shaft.
18. The method of claim 15 , wherein the distal outer section comprises a braided structure configured to transition from the unexpanded state to the radially expanded state upon actuation of the actuation element.
19. The method of claim 15 , wherein removing the one or more clots treats ischemic stroke.