Isolated bacterial strain of the genus
A species of Burkholderia sp with no known pathogenicity to vertebrates but with pesticidal activity (e.g., plants, insects, fungi, weeds and nematodes) is provided. Also provided are natural products derived from a culture of said species and methods of controlling pests using said natural products.
1. A method for inhibiting a pest infestation in a location where inhibition is desired, the method comprising:
applying to said location an effective amount of a fermented composition comprising whole cell broth collected from Burkholderia sp. fermentation, wherein said fermented composition comprises FR901465 to inhibit the pest infestation, the pest infestation comprising one or more of Spodoptera exigua larvae, Euschistus sp., Meloidogyne incognita, Botrytis cinerea, Phytophthora sp., and Trichoplusia ni.
2. The method according to claim 1 , wherein said Burkholderia sp. is Burkholderia A396 (NRRL Accession No. B-50319).
3. The method according to claim 1 , wherein said pest infestation comprises Spodoptera exigua larvae.
4. The method according to claim 3 , wherein said Spodoptera exigua larvae are inhibited by increasing the morality said Spodoptera exigua larvae.
5. The method according to claim 1 , wherein said pest infestation comprises juvenile Meloidogyne incognita VW6.
6. The method according to claim 1 , wherein a mortality of Spodoptera exigua larvae is increased and wherein there is a mortality of mortality of Spodoptera exigua larvae of at least about 50% at said location.
7. The method according to claim 1 , which further comprises applying a second effective amount of the fermented composition in the location where inhibition desired.
8. A method for inhibiting a pest infestation in a location where inhibition is desired, the method comprising:
applying an effective amount of a FR901465 compound to inhibit the pest infestation, the pest infestation comprising one of Spodoptera exigua larvae, Euschistus sp., Meloidogyne incognita, and Trichoplusia ni.
9. The method according to claim 8 , wherein said pest infestation comprises Spodoptera exigua larvae.