Means and methods for using non-excitatory electrical heart failure therapy as a therapy for heart failure with preserved ejection fraction

1 . A method of treating a patient with non-excitatory electrical heart failure therapy, the method comprising:

a. identifying a patient that suffers of heart failure (HF) and presents pulmonary capillary wedge pressure indexed to cardiac output (PCWP/CO) slope greater than 2 mm Hg/L/min;

b. implanting an implantable cardiac electrical stimulation device;

c. providing an effective amount of non-excitatory electrical heart failure therapy using said implantable cardiac electrical stimulation device;

wherein said providing is at least until said HF patient presents a reduction in said PCWP/CO slope and uses said PCWP/CO slope as a target for therapy.

2 . The method according to claim 1 , wherein said non-excitatory electrical heart failure therapy is cardiac contractility modulation therapy.

3 . The method according to claim 1 , wherein the HF condition is HF with preserved ejection fraction (pEF).

4 . The method according to claim 1 , wherein said patient has a hypertrophic right ventricle.

5 . The method according to claim 1 , wherein said patient has a hypertrophic ventricular septum.

6 . The method of claim 1 , wherein said providing is at least until said HF patient presents an increase in cardiac contractility.

7 . The method of claim 1 , wherein said providing is at least until said HF patient presents an increase in cardiac output.

8 . The method of claim 1 , wherein said providing is at least until said HF patient presents a reduction in arrhythmia level.

9 . The method of claim 1 , wherein said providing is at least until said HF patient presents a reduction in cardiac stiffness.