Granted Patent B2

US 12,708,509 · App. 17/857,210 · Granted Aug 18, 2026

Inventors: John Morriss (San Francisco, CA); Matt McLean (San Francisco, CA); Maureen Bensing (Sunnyvale, CA); Jean-Pierre Dueri (Los Gatos, CA); Hanson Gifford, III (Woodside, CA); Katie Miyashiro (Miyashiro, CA); David Jerry Scott (Redwood City, CA); David Trask (Redwood City, CA); Kirsten Valley (Los Altos, CA)

Assignee: Twelve, Inc.

A61F2/2418A61F2/2409A61F2/2433A61F2/2436A61F2/2445A61F2210/0014A61F2220/0008A61F2220/0016A61F2220/0025A61F2220/0041A61F2220/005A61F2220/0066A61F2220/0075A61F2230/0054A61F2230/0065A61F2230/0067A61F2230/0069A61F2230/0071A61F2230/0078A61F2250/0003A61F2250/006A61F2250/0069

Abstract

Claims (25)

1 . A prosthetic heart valve device for treating a native valve having a native annulus and native leaflets, the prosthetic heart valve device including a radially compressed configuration and a radially expanded configuration, the prosthetic heart valve device comprising:

a valve support inner stent expandable from a low-profile configuration for delivery to an expanded configuration for implantation at the native valve;

a prosthetic valve mounted to the valve support inner stent and adapted to allow blood flow in a downstream direction and to block blood flow in an upstream direction; and

an anchoring member outer stent including a first end attached to the valve support and a second end spaced radially from the valve support inner stent such that a radial gap is disposed between the anchoring member outer stent and the valve support inner stent with the prosthetic heart valve device in the radially expanded configuration;

wherein the anchoring member outer stent includes a plurality of rows of cells;

wherein a first row of cells of the plurality of rows of cells disposed adjacent the first end of the anchoring member outer stent includes cells having a first cell size;

wherein a second row of cells of the plurality of rows of cells includes cells having a diamond shape and a second cell size smaller than the first cell size;

wherein the second row of cells is disposed spaced apart from the first end such that the first row of cells is disposed between the second row of cells and the first end;

wherein a third row of cells of the plurality of rows of cells includes cells having a diamond shape and a third cell size that is smaller than the first cell size; and

wherein the second row of cells is disposed between the third row of cells and the first row of cells.

2 . The prosthetic heart valve device of claim 1 , wherein a fourth row of cells of the plurality of rows of cells is disposed between the first end and the first row of cells.

3 . The prosthetic heart valve device of claim 2 , wherein the fourth row of cells includes cells having a diamond shape.

4 . The prosthetic heart valve device of claim 1 , wherein the valve support includes hexagonal shaped cells.

5 . The prosthetic heart valve device of claim 1 , wherein the valve support inner stent includes a plurality of longitudinal struts and a plurality of rows of angled struts, wherein first angled struts of a first row of the plurality of rows angled struts extend from the longitudinal struts in a generally downstream direction, and wherein second angled struts of a second row of the plurality of rows of angled struts adjacent the first row extend from the longitudinal struts in a generally downstream direction.

6 . The prosthetic heart valve device of claim 1 , further comprising a sealing member coupled to an interior surface of the anchoring member outer stent.

7 . The prosthetic heart valve device of claim 6 , wherein the sealing member is sutured to the anchoring member outer stent.

8 . A prosthetic heart valve device for treating a native valve having a native annulus and native leaflets, the prosthetic heart valve device including a radially compressed configuration and a radially expanded configuration, the prosthetic heart valve device comprising:

a valve support inner stent expandable from a low-profile configuration for delivery to an expanded configuration for implantation at the native valve;

a prosthetic valve mounted to the valve support inner stent and adapted to allow blood flow in a downstream direction and to block blood flow in an upstream direction;

an anchoring member outer stent including a first end attached to the valve support inner stent and a second end radially spaced from the valve support inner stent such that a radial gap is disposed between the anchoring member outer stent and the valve support inner stent with the prosthetic heart valve device in the radially expanded configuration, wherein the anchoring member outer stent includes a plurality of rows of diamond-shaped cells, wherein the anchoring member outer stent is attached to the valve support inner stent in the radially compressed configuration and the radially expanded configuration, and wherein the anchoring member inner stent at least partially surrounds the anchoring member inner stent in the radially compressed configuration and the radially expanded configuration; and

a sealing member coupled to an interior surface of the anchoring member outer stent.

9 . The prosthetic heart valve device of claim 8 , wherein the anchoring member outer stent comprises an additional row of cells, wherein each cell of the additional row of cells is larger than each diamond-shaped cell of the plurality of rows of diamond-shaped cells.

10 . The prosthetic heart valve device of claim 8 , wherein the valve support inner stent includes hexagonal shaped cells.

11 . The prosthetic heart valve device of claim 8 , wherein the valve support inner stent includes a plurality of longitudinal struts and a plurality of rows of angled struts, wherein first angled struts of a first row of the plurality of rows angled struts extend from the longitudinal struts in a generally downstream direction, and wherein second angled struts of a second row of the plurality of rows of angled struts adjacent the first row extend from the longitudinal struts in a generally downstream direction.

12 . The prosthetic heart valve device of claim 8 , wherein the sealing member is sutured to the anchoring member outer stent.

Assignments (1)

Continuity (11)

References Cited (400)