IP Library › Granted Patent US 12,383,278
Granted Patent B2
US 12,383,278 · App. 17/857,513 · Granted Aug 12, 2025

Left atrial appendage closure device

Inventors: Jan-Hung Chen (St. Paul, MN); Harishankar Natesan (Shoreview, MN); Thyna M. Chau (Woodbury, MN)
Assignee: Boston Scientific Scimed, Inc.
A61B17/12172A61B17/12031A61B17/12122A61B2017/1205
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Quick Facts
Patent No.
US 12,383,278
App. No.
17/857,513
Granted
Aug 12, 2025
Kind
B2
Abstract

A left atrial appendage closure device may include an expandable framework having a plurality of struts joined at a proximal and distal hub. When the framework is fully constrained in a first position, a first segment of struts extends distally from the distal hub parallel to a central longitudinal axis to a first bend and a second segment of struts extends from the first bend proximally. A first amount of the framework is unconstrained in a second position, where the first segment extends distally from the distal hub parallel to the central longitudinal axis to the first bend, the second segment extends from the first bend proximally and radially outward to a second bend, a third segment of struts extends from the second bend proximally and radially inward to a third bend, and a fourth segment of struts extends from the third bend proximally to within the delivery sheath.

Claims (42)

1. A left atrial appendage closure device, comprising:

an expandable framework having a plurality of struts disposed about a central longitudinal axis, the plurality of struts being joined together at a proximal hub and a distal hub;

wherein when the expandable framework is fully constrained in a first position by a delivery sheath, a first segment of the plurality of struts extends distally from the distal hub to a first bend and a second segment of the plurality of struts extends from the first bend proximally;

wherein a first amount of the expandable framework is unconstrained by the delivery sheath in a second position;

wherein in the second position the first segment of the plurality of struts extends distally from the distal hub to the first bend, the second segment of the plurality of struts extends from the first bend proximally and radially outward to a second bend, a third segment of the plurality of struts extends from the second bend proximally and radially inward to a third bend, and a fourth segment of the plurality of struts extends from the third bend proximally to within the delivery sheath;

wherein a second amount of the expandable framework greater than the first amount is unconstrained by the delivery sheath in a third position;

wherein in the third position the first segment of the plurality of struts extends distally from the distal hub to the first bend, the second segment of the plurality of struts extends from the first bend radially outward generally perpendicular to the central longitudinal axis to the second bend, the third segment of the plurality of struts extends from the second bend proximally and radially inward to the third bend, and the fourth segment of the plurality of struts extends from the third bend proximally toward the proximal hub disposed within the delivery sheath;

wherein a third amount of the expandable framework greater than the second amount is unconstrained by the delivery sheath in a fourth position;

wherein in the fourth position the first segment of the plurality of struts extends distally from the distal hub to the first bend, the second segment of the plurality of struts extends from the first bend distally and radially outward to the second bend, the third segment of the plurality of struts extends from the second bend proximally and radially inward toward the third bend, and the fourth segment of the plurality of struts extends from the third bend proximally toward the proximal hub disposed within the delivery sheath.

2. The left atrial appendage closure device of claim 1 , wherein in the second position the first segment and the second segment form an acute angle opening inwardly toward an interior of the expandable framework.

3. The left atrial appendage closure device of claim 1 , wherein in the third position the second segment and the third segment form an acute angle opening inwardly toward the central longitudinal axis.

4. The left atrial appendage closure device of claim 1 , wherein in the third position the third segment and the fourth segment form an obtuse angle opening outwardly away from the central longitudinal axis.

5. The left atrial appendage closure device of claim 1 , wherein in the fourth position the first segment and the second segment form an obtuse angle opening inwardly toward an interior of the expandable framework.

6. The left atrial appendage closure device of claim 1 , wherein in the fourth position the second segment and the third segment form an acute angle opening inwardly toward the central longitudinal axis.

7. The left atrial appendage closure device of claim 1 , wherein in the fourth position the third segment and the fourth segment form an obtuse angle opening outwardly away from the central longitudinal axis.

8. The left atrial appendage closure device of claim 1 , wherein a fourth amount of the expandable framework greater than the third amount is unconstrained by the delivery sheath in a fifth position;

wherein in the fifth position the first segment of the plurality of struts extends distally from the distal hub to the first bend, the second segment of the plurality of struts extends from the first bend distally and radially outward to the second bend, the third segment of the plurality of struts extends from the second bend proximally to the third bend, and the fourth segment of the plurality of struts extends from the third bend radially inward toward the proximal hub.

9. The left atrial appendage closure device of claim 8 , wherein in the fifth position the first segment and the second segment form an obtuse angle opening inwardly.

10. The left atrial appendage closure device of claim 8 , wherein in the fifth position the second segment and the third segment form an acute angle opening inwardly.

11. The left atrial appendage closure device of claim 8 , wherein in the fifth position the third segment and the fourth segment form an angle of about 90 degrees or less opening inwardly.

12. The left atrial appendage closure device of claim 1 , wherein the distal hub is disposed proximal of the first bend.

13. The left atrial appendage closure device of claim 1 , wherein in the second position the distal hub is disposed distal of the second bend.

14. A left atrial appendage closure device, comprising:

an expandable framework having a plurality of struts disposed about a central longitudinal axis, the plurality of struts being joined together at a proximal hub and a distal hub;

wherein as the expandable framework shifts from fully constrained to fully unconstrained, the expandable framework transitions sequentially through a plurality of positions;

wherein in a first position, a first segment of the plurality of struts extends distally from the distal hub to a first bend and a second segment of the plurality of struts extends from the first bend proximally;

wherein in a second position, the second segment of the plurality of struts, if swept circumferentially around the central longitudinal axis, defines a generally conical shape tapering radially outward in a proximal direction from the first bend toward a second bend;

wherein in a third position, the second segment of the plurality of struts, if swept circumferentially around the central longitudinal axis, defines a generally planar shape oriented generally perpendicular to the central longitudinal axis; and

wherein in a fourth position, the second segment of the plurality of struts, if swept circumferentially around the central longitudinal axis, defines a generally conical shape tapering radially outward in a distal direction from the first bend toward the second bend.

15. The left atrial appendage closure device of claim 14 , wherein in the second position, the distal hub is disposed proximal of the first bend and the distal hub is disposed distal of the second bend.

16. A left atrial appendage closure device system, comprising:

a delivery sheath having a lumen extending therein; and

a left atrial appendage closure device comprising an expandable framework having a plurality of struts disposed about a central longitudinal axis, the plurality of struts being joined together at a proximal hub and a distal hub;

wherein when the expandable framework is disposed within the lumen of the delivery sheath in a first position, a first segment of the plurality of struts extends distally from the distal hub to a first bend and a second segment of the plurality of struts extends from the first bend proximally;

wherein relative axial translation between the delivery sheath and the expandable framework exposes some of the expandable framework in a second position;

wherein in the second position the first segment of the plurality of struts extends distally from the distal hub to the first bend, the second segment of the plurality of struts extends from the first bend proximally and radially outward to a second bend, a third segment of the plurality of struts extends from the second bend proximally and radially inward to a third bend, and a fourth segment of the plurality of struts extends from the third bend proximally to within the delivery sheath;

wherein relative axial translation between the delivery sheath and the expandable framework exposes more of the expandable framework in a third position than in the second position;

wherein in the third position the first segment of the plurality of struts extends distally from the distal hub to the first bend, the second segment of the plurality of struts extends from the first bend radially outward generally perpendicular to the central longitudinal axis to the second bend, the third segment of the plurality of struts extends from the second bend proximally and radially inward to the third bend, and the fourth segment of the plurality of struts extends from the third bend proximally toward the proximal hub disposed within the delivery sheath;

wherein relative axial translation between the delivery sheath and the expandable framework exposes more of the expandable framework in a fourth position than in the third position;

wherein in the fourth position the first segment of the plurality of struts extends distally from the distal hub to the first bend, the second segment of the plurality of struts extends from the first bend distally and radially outward to the second bend, the third segment of the plurality of struts extends from the second bend proximally and radially inward toward the third bend, and the fourth segment of the plurality of struts extends from the third bend proximally toward the proximal hub disposed within the delivery sheath;

wherein relative axial translation between the delivery sheath and the expandable framework exposes all of the expandable framework in a fifth position;

wherein in the fifth position the first segment of the plurality of struts extends distally from the distal hub to the first bend, the second segment of the plurality of struts extends from the first bend distally and radially outward to the second bend, the third segment of the plurality of struts extends from the second bend proximally to the third bend, and the fourth segment of the plurality of struts extends from the third bend radially inward toward the proximal hub.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 5, 2022
From: CHEN, JAN-HUNG; NATESAN, HARISHANKAR; CHAU, THYNA M.
To: BOSTON SCIENTIFIC SCIMED, INC.
Reel/Frame 060399/0244 →
Continuity (2)
Provisional Application 63219696 · Jul 8, 2021
Related Publication 20230010024A1 · Jan 12, 2023
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