IP Library Patent Application 17859877
Patent Application
App. No. 17/859,877

DEVICES, SYSTEMS, AND METHODS FOR RESPIRATORY DISEASE TESTING CROSS-REFERENCE TO RELATED APPLICATIONS

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Quick Facts
Patent No.
US None
App. No.
17/859,877
Abstract

Aspects relate to devices, systems, and methods for non-invasive testing. The device may include a cartridge that analyzes a nasopharyngeal swabbing sample. The device may also include first and second waveguides, where each waveguide is configured to propagate an electromagnetic (EM) wave.

Claims (42)

1 . A non-invasive testing device, the device comprising:

an input configured to receive a sample;

at least a first waveguide in fluidic communication with the input and configured to:

propagate a first electromagnetic (EM) wave; and

vary in a first optical property as a function of the sample;

at least a second waveguide in fluidic communication with the input and configured to:

propagate a second EM wave; and

vary in a second optical property as a function of the sample; and

at least a sensor in communication with the at least a first waveguide and the at least a second waveguide and configured to detect, using the first EM wave and the second EM wave, a first constituent of the sample and a second constituent of the sample, as a function of a first variance in the first optical property and a second variance in the second optical property.

2 . The device of claim 1 , further comprising a multiplexor in communication with the at least a first waveguide, the at least a second waveguide, and the sensor, wherein the multiplexor is configured to multiplex the first EM wave and the second EM wave.

3 . The device of claim 1 , wherein the at least a second waveguide comprises a ring resonator.

4 . The device of claim 1 , wherein the at least a first waveguide is configured to provide communication between the first EM wave and a portion of the sample by propagating an evanescent wave from a surface.

5 . The device of claim 1 , wherein the first optical property includes an index of refraction of the at least a first waveguide.

6 . The device of claim 1 , wherein the at least a first waveguide is configured to provide communication between the first EM wave and a portion of the sample by propagating surface plasmons upon a surface.

7 . The device of claim 1 , wherein a first surface is coated with a capture antibody configured to selectively bind to a first antigen and vary the first optical property.

8 . The device of claim 1 , wherein the microfluid device is configured to contain a first marker, wherein the first marker is configured to selectively conjugate the first antigen and vary the first optical property.

9 . The device of claim 1 , further comprising:

A computing device in communication with the sensor and configured to:

receive, from the at least a sensor, at least a signal representing the at least a first constituent and the at least a second constituent; and

communicate, with a remote device, at least a first datum representing the at least a first constituent and at least a second datum representing the at least a second constituent.

10 . The device of claim 1 , wherein the remote device is configured to process the at least a first datum and the at least a second datum; and

recognize a variant of the substance, as a function of processing the at least a first datum and the at least a second datum.

11 . A method of detection, the method comprising:

receiving, by an input of a housing, a sample;

propagating, by at least a first waveguide in fluidic communication with the input, a first electromagnetic (EM) wave;

varying, by the at least a first waveguide, in a first optical property as a function of the sample;

propagating, by at least a second waveguide in fluidic communication with the input, a second electromagnetic (EM) wave;

varying, by the at least a second waveguide, in a second optical property as a function of the sample;

detecting, by at least a sensor in communication with the at least a first waveguide and the at least a second waveguide, using the first EM wave and the second EM wave, a first constituent of the sample and a second constituent of the sample, as a function of a first variance in the first optical property and a second variance in the second optical property.

12 . The method of claim 11 , further comprising a multiplexor in communication with the at least a first waveguide, the at least a second waveguide, and the sensor, wherein the multiplexor is configured to multiplex the first EM wave and the second EM wave.

13 . The method of claim 11 , wherein the at least a second waveguide comprises a ring resonator.

14 . The method of claim 11 , wherein the at least a first waveguide is configured to provide communication between the first EM wave and a portion of the sample by propagating an evanescent wave from a surface.

15 . The method of claim 11 , wherein the first optical property includes an index of refraction of the at least a first waveguide.

16 . The method of claim 11 , wherein the at least a first waveguide is configured to provide communication between the first EM wave and a portion of the sample by propagating surface plasmons upon a surface.

17 . The method of claim 11 , wherein a first surface is coated with a capture antibody configured to selectively bind to a first antigen and vary the first optical property.

18 . The method of claim 11 , wherein the microfluid device is configured to contain a first marker, wherein the first marker is configured to selectively conjugate the first antigen and vary the first optical property.

19 . The method of claim 11 , further comprising:

a computing device in communication with the sensor and configured to:

receive, from the at least a sensor, at least a signal representing the at least a first constituent and the at least a second constituent; and

communicate, with a remote device, at least a first datum representing the at least a first constituent and at least a second datum representing the at least a second constituent.

20 . The method of claim 11 , wherein the remote device is configured to process the at least a first datum and the at least a second datum; and

recognize a variant of the substance, as a function of processing the at least a first datum and the at least a second datum.

Assignments (4)
RELEASE OF SECURITY INTEREST Recorded May 15, 2026
From: ALTER DOMUS (US) LLC
To: SIPHOX, INC.
Reel/Frame 074674/0493 →
SECURITY INTEREST Recorded Feb 13, 2026
From: SIPHOX, INC.
To: ALTER DOMUS (US) LLC
Reel/Frame 073779/0457 →
SECURITY INTEREST Recorded Jan 23, 2026
From: SIPHOX, INC.
To: FIRST-CITIZENS BANK & TRUST COMPANY
Reel/Frame 073565/0772 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 11, 2024
From: RYBAKOVA, YULIA; CHAPMAN, COLE; SIEK, GORDON; COBB, JORDAN; ALJOHANI, EBRAHIM
To: SIPHOX, INC.
Reel/Frame 067684/0150 →