IP Library › Granted Patent US 12,042,501
Granted Patent B2
US 12,042,501 · App. 17/860,872 · Granted Jul 23, 2024

Metal protoporphyrin for treatment of BK virus

Inventors: Donald Jeffrey Keyser (Southlake, TX); Alvaro F. Guillem (Lantana, TX); Bhupinder Singh (Phoenix, AZ); Stacey Ruiz (Lantana, TX)
Assignee: Renibus Therapeutics, Inc.
A61K31/555A61K47/18A61K47/26A61P31/12
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Quick Facts
Patent No.
US 12,042,501
App. No.
17/860,872
Granted
Jul 23, 2024
Kind
B2
Abstract

The inactivation of BK virus in patients diagnosed with BK virus, those receiving a kidney that is infected or suspected of being infected by BK virus, or in the transplanted kidney before, during, and/or after transplant surgery is described.

Claims (5)

1. A method of treating a patient having been diagnosed with BK virus, comprising administering an amount of metal protoporphyrin effective to reduce or eliminate the effects of the BK virus.

2. The method of claim 1 , wherein the metal protoporphyrin is tin protoporphyrin (SnPP).

3. The method of claim 1 , wherein the patient has undergone kidney transplant.

4. The method of claim 1 , wherein the metal protoporphyrin is administered at a dose rate ranging from 0.06 to 1.125 mg/kg/day.

5. The method of claim 1 , wherein the metal protoporphyrin is administered at a daily dose ranging from 5 to 90 mg.

Assignments (2)
SECURITY INTEREST Recorded Jun 4, 2026
From: RENIBUS THERAPEUTICS, INC.
To: AVENUE VENTURE OPPORTUNITIES FUND II, L.P.
Reel/Frame 074858/0020 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 28, 2022
From: KEYSER, DONALD JEFFREY; GUILLEM, ALVARO F.; SINGH, BHUPINDER; RUIZ, STACEY
To: RENIBUS THERAPEUTICS, INC.
Reel/Frame 061246/0712 →
Continuity (2)
Provisional Application 63220625 · Jul 12, 2021
Related Publication 20230023467A1 · Jan 26, 2023