Granted Patent B2

US 12,324,728 · App. 17/861,074 · Granted Jun 10, 2025

Inventors: Timothy Mark Robinson (Shillingstone, GB); Christopher Brian Locke (Bournemouth, GB); Benjamin Andrew Pratt (Poole, GB); Larry Tab Randolph (San Antonio, TX); Justin Alexander Long (Lago Vista, TX); James Courage (San Antonio, TX); Diwi L. Allen (San Antonio, TX); Kristine M. Kieswetter (San Antonio, TX)

Assignee: Solventum Intellectual Properties Company

A61F13/05A61F13/01021A61F13/0206A61F13/148A61L27/16A61L27/18A61L27/34A61L27/54A61M1/85A61M1/90A61M1/915A61F2013/00157A61F2013/00357A61M1/92A61M2210/1017A61M2210/1021

Abstract

Claims (24)

1. An apparatus for filling a wound, the apparatus comprising:

an array of interconnected polymeric ovules having a truncated ellipsoidal shape, wherein:

each set of four interconnected ovules defines a fluid pathway extending perpendicularly through the array;

each truncated ellipsoidal shape comprises an approximately elliptical contact surface at each contact surface between two interconnected ovules; and

each interconnected polymeric ovule has its longest principal axis oriented substantially perpendicular to the array.

2. The apparatus of claim 1 , wherein the array comprises:

at least three columns comprising two edge columns and at least one central column; and

at least three rows comprising two edge rows and at least one central row, and

wherein each set of four interconnected ovules is arranged in two of the at least three rows and two of the at least three columns.

3. The apparatus of claim 1 , wherein the array comprises four corner ovules, at least four edge ovules, at least one central ovule, and at least four fluid pathways interstitially therebetween, each central ovule having a truncated ellipsoidal shape with four elliptical contact surfaces, each edge ovule having a truncated ellipsoidal shape with three elliptical contact surfaces, and each corner ovule having a truncated ellipsoidal shape with two elliptical contact surfaces.

4. The apparatus of claim 1 , wherein the interconnected ovules are comprised of a polyolefin, a polyester, a polyamide, a polystyrene, a polydiolefin, a polyacrylonitrile, a polysiloxane, or a copolymer or combination thereof.

5. The apparatus of claim 1 , wherein each interconnected ovule has its two principal axes other than the longest principal axis, respectively, oriented at approximately a 45° angle to a row direction of the array and at approximately a 45° angle to a column direction of the array.

6. The apparatus of claim 1 , wherein each of the interconnected ovules are truncated only at one end of the longest principal axis and at each surface where the ovules are interconnected.

7. The apparatus of claim 1 , wherein the array of interconnected ellipsoids or interconnected ovules has an upper surface and a lower surface, and wherein the upper surface or the lower surface or both has a hardness from about 0 Shore A to about 25 Shore A.

8. The apparatus of claim 7 , wherein the upper surface or the lower surface or both has a coating disposed thereon that exhibits a hardness of at least 55 Shore A.

9. The apparatus of claim 8 , wherein the coating is comprised of a cellulosic material, a polyester, a polyamide, a polycarbonate, a perhalogenated polyolefin, an aramid, a polybenzimidazole, a polysulfone, or a copolymer, combination, or cross-linked gel thereof.

10. The apparatus of claim 1 , wherein at least a portion of the interconnected ellipsoids or at least a portion of the interconnected ovules comprise one or more grooves on an outer surface of each ellipsoid or of each ovule that extend at least partially in a direction of its longest principal axis.

11. The apparatus of claim 10 , wherein each groove has an average depth no more than 30% of a diameter of each interconnected ovule or of each interconnected ellipsoid along a principal axis direction other than the longest principal axis.

12. The apparatus of claim 1 , wherein a longest principal axis of each interconnected ellipsoid or each interconnected ovule is from about 3 mm to about 6 mm.

13. The apparatus of claim 12 , wherein each principal axis other than the longest principal axis of each interconnected ellipsoid or each interconnected ovule is from about 2 mm to about 4 mm.

14. The apparatus of claim 1 , wherein each fluid pathway has a minimum width dimension from about 500 microns to about 1500 microns.

15. The apparatus of claim 1 , wherein the apparatus is translucent.

16. The apparatus of claim 1 , further comprising a wound healing agent in or on the array, the wound healing agent comprising a non-steroidal anti-inflammatory drug, a steroid, an anti-inflammatory cytokine, an anaesthetic, an antiseptic, an antimicrobial agent, a growth factor, a peptide, a microRNA, an antioxidant, or a combination thereof.

17. The apparatus of claim 16 , wherein the antimicrobial agent comprises silver, a silver salt, a tetracycline, a beta-lactam, a macrolide, an aminoglycoside, a fluoroquinolone, a cellulose ethyl sulfonate, or a combination thereof.

Assignments (4)

Continuity (3)

References Cited (199)