Single insertion delivery system for treating embolism and associated systems and methods
Systems and methods for the intravascular treatment of clot material within a blood vessel of a human patient are disclosed herein. A method in accordance with embodiments of the present technology can include, for example, engaging an interventional device of a catheter system with clot material in a blood vessel and withdrawing the interventional device and the portion of the clot material through a guide catheter. In some embodiments, the catheter system can include an attachment/valve member coupled to a proximal portion of the guide catheter, and the method can include unsealing the attachment/valve member to facilitate withdrawing the interventional device through the attachment/valve member without significant retention of clot material within the attachment/valve member. The method can further include resealing and aspirating the guide catheter before advancing another interventional device to the clot material to again engage and remove clot material from the blood vessel.
1. A vacuum aspiration system for removing clot material from a blood vessel of a patient, comprising:
a housing defining a chamber having a first end portion and a second end portion, wherein the housing includes a port at the first end portion;
a cap at the second end portion of the housing, wherein the cap has a fluid connector configured to be connected to tubing fluidically coupled to a source of aspiration;
a flow path extending through the housing from the port to the fluid connector of the cap;
a catheter in fluid communication with the flow path, wherein the catheter is flexible, wherein the catheter is shaped and sized to be percutaneously inserted into a vasculature of the patient and advanced into the blood vessel of the patient to proximate to the clot material, and wherein the port of the housing is configured to be coupled to the catheter;
a flow regulator configured to regulate fluid flow through the flow path, wherein the flow regulator comprises a valve assembly in the housing between the first end portion and the second end portion;
a first operator actuated control configured to regulate fluid flow, wherein the first operator actuated control comprises an actuation mechanism that controls vacuum application to the catheter;
a second operator actuated control configured to turn the fluid flow off with the catheter percutaneously inserted into the vasculature of the patient and advanced into the blood vessel of the patient to proximate to the clot material; and
a filter in the housing along the flow path.
2. The vacuum aspiration system of claim 1 wherein the valve assembly comprises a check valve that allows flow in a first direction along the flow path and prevents flow in a second direction along the flow path opposite the first direction.
3. The vacuum aspiration system of claim 1 wherein:
the second operator actuated control comprises a valve between the housing and the catheter.
4. The vacuum aspiration system of claim 3 wherein the actuation mechanism comprises a lever configured to adjust a vacuum pressure applied to the catheter via the flow path.
5. The vacuum aspiration system of claim 1 wherein the filter includes a filter body having a first end portion and a second end portion, wherein the second end portion defines a mouth, and wherein the filter is positioned with the first end portion nearer to the catheter along the flow path than the second end portion.
6. The vacuum aspiration system of claim 5 wherein the flow path extends through filter body and through the mouth.
7. A vacuum aspiration system for removing clot material from a blood vessel of a patient, comprising:
a housing defining a chamber having a first end portion and a second end portion, wherein the housing includes a port at the first end portion;
a cap at the second end portion of the housing, wherein the cap has a fluid connector configured to be connected to tubing fluidically coupled to a source of aspiration;
a flow path extending through the housing from the port to the fluid connector of the cap;
a catheter in fluid communication with the flow path, wherein the catheter is flexible, wherein the catheter is shaped and sized to be percutaneously inserted into a vasculature of the patient and advanced into the blood vessel of the patient to proximate to the clot material, and wherein the port of the housing is configured to be coupled to the catheter;
a flow regulator configured to regulate fluid flow through the flow path, wherein the flow regulator comprises a valve assembly in the housing between the first end portion and the second end portion, and wherein the valve assembly comprises a check valve that allows flow in a first direction along the flow path and prevents flow in a second direction along the flow path opposite the first direction;
a first operator actuated control configured to regulate fluid flow, wherein the first operator actuated control comprises an actuation mechanism that controls vacuum application to the catheter; and
a second operator actuated control configured to turn the fluid flow off, wherein the second operator actuated control comprises a valve between the housing and the catheter; and
a filter in the housing along the flow path.
8. The vacuum aspiration system of claim 7 wherein the actuation mechanism comprises a lever configured to adjust a vacuum pressure applied to the catheter via the flow path.
9. The vacuum aspiration system of claim 7 wherein the second operator actuated control comprises a valve between the housing and the catheter.
10. The vacuum aspiration system of claim 7 wherein the actuation mechanism comprises a lever configured to adjust a vacuum pressure applied to the catheter via the flow path.
11. The vacuum aspiration system of claim 7 wherein the filter includes a plurality of pores sized to inhibit clot material from flowing therethrough and to permit blood to flow therethrough.
12. The vacuum aspiration system of claim 1 wherein the filter includes a plurality of pores sized to inhibit clot material from flowing therethrough and to permit blood to flow therethrough.
13. The vacuum aspiration system of claim 7 wherein the second operator actuated control is configured to turn the fluid flow off with the catheter percutaneously inserted into the vasculature of the patient and advanced into the blood vessel of the patient to proximate to the clot material.