IP Library Granted Patent US 11,837,197
Granted Patent B2
US 11,837,197 · App. 17/869,235 · Granted Dec 5, 2023

System and method for generating a 2D image using mammography and/or tomosynthesis image data

Inventors: Kevin Kreeger (Sunnyvale, CA); Andrew P. Smith (Lexington, MA); Ashwini Kshirsagar (Cupertino, CA); Jun Ge (Cupertino, CA); Xiangwei Zhang (Fremont, CA); Haili Chui (Fremont, CA); Christopher Ruth (Boxford, MA); Yiheng Zhang (Reading, MA); Liyang Wei (San Jose, CA); Jay Stein (Boston, MA)
Assignee: Hologic, Inc.
G09G5/377A61B6/025A61B6/502A61B6/5205A61B6/5235A61B6/5241G06T7/30G06T11/006G06T11/008G06T2207/10081G06T2207/20221G06T2207/30068G06T2211/436
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Quick Facts
Patent No.
US 11,837,197
App. No.
17/869,235
Granted
Dec 5, 2023
Kind
B2
Abstract

The invention includes a method including the steps of obtaining a plurality of images, each of the images in the plurality having at least one corresponding region, generating a merged image, the merged image also having the corresponding region. The step of generating includes selecting an image source from the plurality of images to source image data for the corresponding region in the merged image by comparing attributes of the corresponding regions of the plurality of images to identify the image source having preferred attributes.

Claims (33)

1. A method for processing breast image data, the method comprising:

obtaining a plurality of projection images Tp of a breast, each of the projection images Tp in the plurality having a corresponding region;

identifying features within the respective corresponding region of each of the projection images Tp;

assigning a weight to the respective corresponding region of each projection images Tp based on the identified features;

generating a synthesized 2D reconstructed image slab Tr of the breast, the synthesized 2D reconstructed image slab Tr also having the corresponding region, wherein the synthesized 2D reconstructed image slab Tr is generated by selecting a source image from the plurality of projection images Tp to source image data for the corresponding region in the synthesized 2D reconstructed image slab Tr by comparing the assigned weights of the respective corresponding region of the plurality of projection images Tp;

generating, from the projection images Tp, a synthesized 2D mammography image of an entire thickness of the breast, wherein the synthesized 2D mammography image of the entire thickness of the breast contains the corresponding regions;

displaying the synthesized 2D mammography image of the entire thickness of the breast;

receiving, in the displayed synthesized 2D mammography image of the entire thickness of the breast, a selection of the corresponding region; and

displaying the synthesized 2D reconstructed image slab Tr based on the selection.

2. The method of claim 1 , further comprising generating a map for the synthesized 2D reconstructed image slab Tr, wherein the map identifies the source image of the corresponding region in the synthesized 2D reconstructed image slab Tr.

3. The method of claim 1 , wherein the identified features include at least one of spiculated lesions, masses, and calcifications.

4. The method of claim 1 , wherein the source image for the corresponding region in the synthesized 2D reconstructed image slab Tr is selected based on having a comparatively highest assigned weight for the corresponding region of all images of the plurality of projection images Tp.

5. The method of claim 1 , wherein the corresponding region in the synthesized 2D reconstructed image slab Tr includes at least one pixel from the source image.

6. The method of claim 1 , wherein a size of the corresponding region in the synthesized 2D reconstructed image slab Tr is statically pre-defined.

7. The method of claim 1 , wherein a size of the corresponding region in the synthesized 2D reconstructed image slab Tr varies in accordance with a varying threshold of the source image.

8. A workstation for reviewing breast image data, the workstation comprising:

a processor;

a display operatively coupled with the processor; and

an interface operatively coupled with the processor, wherein the processor and interface are configured to selectively cause the processor to:

obtain a plurality of projection images Tp of a breast, each of the projection images Tp in the plurality having a corresponding region;

identify features within the respective corresponding region of each of the projection images Tp;

assign a weight to the respective corresponding region of each projection images Tp based on the identified features;

generate a synthesized 2D reconstructed image slab Tr of the breast, the synthesized 2D reconstructed image slab Tr also having the corresponding region, wherein the synthesized 2D reconstructed image slab Tr is generated by selecting a source image from the plurality of projection images Tp to source image data for the corresponding region in the synthesized 2D reconstructed image slab Tr by comparing the assigned weights of the respective corresponding region of the plurality of projection images Tp;

generate, from the projection images Tp, a synthesized 2D mammography image of an entire thickness of the breast, wherein the synthesized 2D mammography image of the entire thickness of the breast contains the corresponding regions;

display the synthesized 2D mammography image of the entire thickness of the breast;

receive, in the displayed synthesized 2D mammography image of the entire thickness of the breast, a selection of the corresponding region; and

display the synthesized 2D reconstructed image slab Tr based on the selection.

9. The workstation of claim 8 , wherein the processor and interface are further configured to selectively cause the processor to generate a map for the synthesized 2D reconstructed image slab Tr, wherein the map identifies the source image of the corresponding region in the synthesized 2D reconstructed image slab Tr.

10. The workstation of claim 8 , wherein the identified features include at least one of spiculated lesions, masses, and calcifications.

11. The workstation of claim 8 , wherein the source image for the corresponding region in the synthesized 2D reconstructed image slab Tr is selected based on having a comparatively highest assigned weight for the corresponding region of all images of the plurality of projection images Tp.

12. The workstation of claim 8 , wherein the corresponding region in the synthesized 2D reconstructed image slab Tr includes at least one pixel from the source image.

13. The workstation of claim 8 , wherein a size of the corresponding region in the synthesized 2D reconstructed image slab Tr is statically pre-defined.

14. The workstation of claim 8 , wherein a size of the corresponding region in the synthesized 2D reconstructed image slab Tr varies in accordance with a varying threshold of the source image.

Assignments (4)
SECURITY INTEREST Recorded Apr 8, 2026
From: BIOTHERANOSTICS, INC.; GEN-PROBE INCORPORATED; GEN-PROBE PRODESSE, INC.; CYTYC CORPORATION; SUROS SURGICAL SYSTEMS, INC.; GYNESONICS, INC.; BOLDER SURGICAL, LLC; FAXITRON BIOPTICS, LLC; HEALTH BEACONS, INC.; HOLOGIC, INC.
To: ROYAL BANK OF CANADA, AS COLLATERAL AGENT
Reel/Frame 075462/0440 →
SECURITY INTEREST Recorded Oct 11, 2022
From: HOLOGIC, INC.; FAXITRON BIOPTICS, LLC; BIOTHERANOSTICS, INC.; GEN-PROBE INCORPORATED
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 061639/0513 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 10, 2022
From: KREEGER, KEVIN; SMITH, ANDREW P.; KSHIRSAGAR, ASHWINI; GE, JUN; ZHANG, XIANGWEI; CHUI, HAILI; RUTH, CHRISTOPHER; ZHANG, YIHENG; WEI, LIYANG; STEIN, JAY
To: HOLOGIC, INC.
Reel/Frame 060767/0404 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 20, 2022
From: KREEGER, KEVIN; SMITH, ANDREW P.; KSHIRSAGAR, ASHWINI; GE, JUN; ZHANG, XIANGWEI; CHUI, HAILI; RUTH, CHRISTOPHER; ZHANG, YIHENG; WEI, LIYANG; STEIN, JAY
To: HOLOGIC, INC.
Reel/Frame 060566/0769 →